The Joe Cohen Show

In this episode of The Joe Cohen Show, Joe takes a personal and scientific look at monogamy, exploring why some people feel more content in exclusive relationships than others.  He breaks down what research says about the hormone vasopressin and its role in bonding, loyalty, and long-term attachment, drawing from both animal studies and genetic findings.  Joe also shares a surprising result from his own supplement routine, where taking L-arginine and glycine seemed to shift his natural tendencies toward greater monogamy.  It's a unique mix of biohacking, hormones, and human behavior you won’t want to miss. - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamps: (00:00) Introduction to the Joe Cohen Show (00:16) Exploring Monogamy and Personal Tendencies (02:56) The Role of Vasopressin in Monogamy (05:44) Vasopressin's Impact on Human Relationships (14:14) Personal Experiment with Supplements (22:42) Conclusion and Recommendations

In this special episode, Joe sits down with health coach and SelfDecode Pro user Joline Schaaphok to walk through her personalized health insights using genetic data.  They explore everything from supplement recommendations and food sensitivities to overlooked risk factors like anemia and cardiovascular health. It’s a real-time example of how genetic reports, labs, and lifestyle data can work together to uncover actionable insights.  Whether you're a practitioner, a biohacker, or just curious about precision health, this live analysis offers a behind-the-scenes look at how to turn data into meaningful change. - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamps: (00:00) Introduction to the Joe Cohen Show (00:16) Meet Joline Schaaphok (02:02) Diving into Joline's Genetic Results (03:32) Macronutrient and Vitamin Recommendations (04:41) Food Sensitivities and Allergies (05:46) Health Overview Report: Genetic and Lifestyle Insights (09:27) Supplement Recommendations and Customization (23:29) Refining the Supplement List (24:08) Optimizing the Daily Regimen (25:29) Detailed Regimen Breakdown (28:15) Advanced Filtering Techniques (33:11) Addressing Anemia and Food Allergies (39:17) Comprehensive Lab Testing (40:50) Genetic Insights and Recommendations (43:10) Final Thoughts and Next Steps

In this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider.  Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overall well-being. They dive into the specifics of how genetic insights can personalize treatment plans, leading to better, faster results.  Whether it's diagnosing mental health issues more accurately or managing physical health conditions like diabetes and inflammation, Sasha highlights the transformative impact of personalized medicine.  Tune in to understand why integrating genetic information into healthcare is not just an innovation but a necessity. - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamp: (00:00) - Introduction to the Joe Cohen Show (00:16) - Meet Sasha Powell (00:56) - Using DNA for Personalized Health Solutions (01:24) - Weight and Hormone Management Strategies (03:11) - Blood Sugar Regulation and Diet Recommendations (07:25) - Mental Health and Genetic Insights (10:59) - The Role of Neurochemistry in Treatment Plans (13:48) - Personalized Supplement Recommendations (30:10) - The Importance of Methylation in Health (34:03) - Utilizing Self Decode for Comprehensive Health Management (38:31) - Optimizing Quality of Life (39:06) - Longevity Screener Insights (39:34) - Clinical Overview Report (40:30) - Health Overview Report (41:44) - Lab Data and Clinical Recommendations (45:15) - Family Planning and Genetic Risks (45:57) - Integrating Lab Tests and Genetic Data (48:44) - Using SelfDecode in Clinical Practice (58:56) - The Future of Healthcare with AI (01:04:26) - Organic Acids Test and Lab Considerations (01:08:08) - Concluding Thoughts and Recommendations

In this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation.  He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus. Joe also breaks down the symptoms tied to excess glutamate, from headaches and insomnia to mood swings and neurological issues. He discusses why certain people are more sensitive to glutamate due to genetic differences, and outlines what’s helped him manage it, including specific doses of NAC, glycine, B6, vitamin C, and more. This episode offers a practical, firsthand look at how glutamate functions, what throws it out of balance, and what can be done to bring it under control. - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/  Timestamps: (00:00) - Introduction (00:16) - Understanding Glutamate and Its Effects (04:32) - Personal Experiments with Glutamate (08:22) - Supplements and Strategies to Lower Glutamate (18:31) - Symptoms and Conditions Related to High Glutamate (20:20) - Genetic Factors and Glutamate (22:13) - Conclusion

In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing.  Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers. Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy.  The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space. Whether you’re a health professional or someone trying to optimize your gut, this episode will help you separate science from sales. 📌 Topics covered: microbiome testing technology, bioinformatics, probiotic strains, sequencing methods, red flags in wellness tech - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ (00:00) - Introduction to the Joe Cohen Show (00:16) - Meet Kiran Krishnan (01:07) - Understanding Microbiome Testing (03:01) - The Importance of Whole Genome Sequencing (04:48) - Challenges in Microbiome and Genetic Testing (05:42) - Critique of 16S Ribosomal RNA Sequencing (11:58) - Issues with Viome and Other Testing Companies (21:14) - Complexities of Microbiome Mapping (23:27) - Validating Microbiome Tests (27:04) - The Future of Microbiome Technology (28:10) - Advancements in Genome Sequencing (29:18) - Challenges in Microbiome Analysis (30:40) - Economic Realities of Sequencing (31:57) - Company Strategies and Ethics (33:49) - Benefits of Microbiome Testing (35:12) - Probiotics and Gut Health (38:20) - Top Probiotic Strains (43:00) - Importance of Specific Strains (52:52) - Concluding Thoughts on Probiotics