TSOT155: Logic String, From Admitted "Nanoparticles ARE Toxic" to "Then Why the Hell Are You Putting Them in 'Vaccines' and 'Medicine'????!!"

In revisiting QROT-063 to add details to the episode, I ordered the journal articles into a logic string that really just tells the story, basically just from the titles of the articles.  (Related episodes include TSOT025, TSOT026, QROT-080) The logic string (then repeated further down with the articles listed. See the full cites at the QROT-063 show description or by following the links. 1. Graphene oxide (and by implications most or all of these artificially-small nanoparticles) are toxic. 2. But we're GOING to use them anyway. 3. We have an excuse anyway - adjuvants MUST have some toxicity, AND we can use them as a platform / carrier to deliver the "drugs" or "vaccines" to parts of the body they wouldn't otherwise reach. 4. We'll "mitigate" something that is inherently toxic, by making it "less so" (But REALLY, we'll just "observe" how the body obviously and already mitigates the best it can and we'll call it good) 5. How we'll TRICK the body into not responding to its full capability to this very toxic load.  ==================================================== 1. Graphene oxide (and by implications most or all of these artificially-small nanoparticles) are toxic. * Graphene-Based Nanomaterials Toxicity in Fish. [https://pubmed.ncbi.nlm.nih.gov/30413975/]  * Graphene oxide interaction with Lemna minor: Root barrier strong enough to prevent nanoblade-morphology-induced toxicity [https://www.bohrium.com/en/paper-details/graphene-oxide-interaction-with-lemna-minor-root-barrier-strong-enough-to-prevent-nanoblade-morphology-induced-toxicity/813324948893335553-2981].  * Sublethal toxicity of graphene oxide in Caenorhabditis elegans under multi-generational exposure [https://www.sciencedirect.com/science/article/pii/S0147651321011763]. * Toxicity Studies on Graphene-Based Nanomaterials in Aquatic Organisms: Current Understanding. [https://www.researchgate.net/publication/343537389_Toxicity_Studies_on_Graphene-Based_Nanomaterials_in_Aquatic_Organisms_Current_Understanding]  * Phytotoxicity of Graphene Family Nanomaterials and Its Mechanisms: A Review [https://pmc.ncbi.nlm.nih.gov/articles/PMC6506787/]. * Toxicological Evaluation of Graphene-Family Nanomaterials. [https://pubmed.ncbi.nlm.nih.gov/31492205/]  * Cytotoxicity of Graphene Oxide and Graphene in Human Erythrocytes and Skin Fibroblasts [https://pubs.acs.org/doi/10.1021/am200428v].  * Biomolecular Interactions and Biological Responses of Emerging Two-Dimensional Materials and Aromatic Amino Acid Complexes [https://pubs.acs.org/doi/10.1021/acsami.6b04571].  * Hard corona composition and cellular toxicities of the graphene sheets [https://www.sciencedirect.com/science/article/abs/pii/S0927776513002361?via%3Dihub].  * Graphene Oxide Touches Blood: In Vivo Interactions of Bio-Coronated 2D Materials [https://pubs.rsc.org/en/content/articlehtml/2019/nh/c8nh00318a].  2. But we're GOING to use them anyway.  (because "new tech", so we'll get the FDA approval and can charge greater prices, and our tech can be patentable! Who cares if it is really more effective than 100-year-old treatments or anywhere near as safe!!) * COVID-19 Vaccine Frontrunners and Their Nanotechnology Design [https://pubs.acs.org/doi/10.1021/acsnano.0c07197].  * Graphene oxide: a carrier for pharmaceuticals and a scaffold for cell interactions [https://pubmed.ncbi.nlm.nih.gov/25579346/].  * Graphene and graphene oxide as new nanocarriers for drug delivery applications. [https://www.sciencedirect.com/science/article/abs/pii/S174270611300408X?via%3Dihub]  * Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. [https://pmc.ncbi.nlm.nih.gov/articles/PMC5522963/] [Touches on toxicity and "safety" approaches too] * Graphene: A Comprehensive Review [https://pubmed.ncbi.nlm.nih.gov/27397067/].  3. We have an excuse anyway - adjuvants MUST have some toxicity, AND we can use them as a platform / carrier to deliver the "drugs" or "vaccines" to parts of the body they wouldn't otherwise reach. * Nanomaterial-based vaccine adjuvants [https://escholarship.org/uc/item/2tj937wn]. 4. We'll "mitigate" something that is inherently toxic, by making it "less so" (But REALLY, we'll just "observe" how the body obviously and already mitigates the best it can and we'll call it good) * Dependence of Graphene Oxide (GO) Toxicity on Oxidation Level, Elemental Composition, and Size [https://pmc.ncbi.nlm.nih.gov/articles/PMC8508828/].  * Improved In Vitro and In Vivo Biocompatibility of Graphene Oxide through Surface Modification: Poly(Acrylic Acid)-Functionalization is Superior to PEGylation [https://pubs.acs.org/doi/abs/10.1021/acsnano.6b00539] * Protein corona-mediated mitigation of cytotoxicity of graphene oxide. [https://pubmed.ncbi.nlm.nih.gov/21500856/] [This one also touches on the next category - tricking the body] * Hard corona composition and cellular toxicities of the graphene sheets [https://www.sciencedirect.com/science/article/abs/pii/S0927776513002361?via%3Dihub]. * Protein corona mitigates the cytotoxicity of graphene oxide by reducing its physical interaction with cell membrane [https://www.researchgate.net/publication/281338114_Protein_corona_mitigates_the_cytotoxicity_of_graphene_oxide_by_reducing_its_physical_interaction_with_cell_membrane]. * Insight into the Interaction of Graphene Oxide with Serum Proteins and the Impact of the Degree of Reduction and Concentration [https://pubs.acs.org/doi/abs/10.1021/acsami.5b01874].  5. How we'll TRICK the body into not responding to its full capability to this very toxic load. (Spoiler: They pre-treat it with WEAKENED human blood that does not fully mark it as the threat it is, so that YOUR blood thinks YOUR body already marked it, so it passes through!) * Mailänder, Volker & Simon, Johanna & Müller, Laura & Kokkinopoulou, Maria & Lieberwirth, Ingo & Morsbach, Svenja & Landfester, Katharina. (2018). Exploiting the biomolecular corona: Pre-coating of nanoparticles enables controlled cellular interactions. [https://pubs.rsc.org/en/content/articlehtml/2018/nr/c8nr03331e] Nanoscale. 10. 10.1039/C8NR03331E.   MISCELLANEOUS (Not directly relevant to the logic string, but certainly relevant to the rat bastards' plans) *  Improved Aliivibrio fischeri based-toxicity assay: Graphene-oxide as a sensitivity booster with a mobile-phone application [https://scite.ai/reports/improved-aliivibrio-fischeri-based-toxicity-assay-Nlg1vrlg].  * The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions. [https://pubmed.ncbi.nlm.nih.gov/26502273/] [This one appears to be, but I've not delved, more about hybrid bioengineered nanomaterial, see also an article called The Hybrid Nano-Biointerface between Proteins/Peptides and Two-Dimensional Nanomaterials] * Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review [https://pubs.acs.org/doi/10.1021/tx200339h].