This Week in Virology

TWiV discusses Sen. Cassidy calling for ACIP meeting delay, RFK Jr. abandons GAVI, millions of children at risk as global vaccination rates fall, RFK Jr. grilled by Congress, autism rates have increased 60-fold due to changed definitions, deep mutational scanning of rabies virus glyoprotein, and and proton gradient and incomplete TCA cycle in a giant virus. Hosts: Vincent Racaniello [https://en.wikipedia.org/wiki/Vincent_Racaniello], Rich Condit [https://mgm.ufl.edu/profile/condit-rich/], Brianne Barker [https://bbarkerdrew.com/], and Angela Mingarelli Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Support science education  [https://www.microbe.tv/contribute]at MicrobeTV * Sen. Cassidy calls for ACIP delay [https://www.nytimes.com/2025/06/24/us/politics/cassidy-kennedy-vaccine-committee.html] (NYTimes) * RFK Jr. stops GAVI funding [https://www.nytimes.com/2025/06/25/health/kennedy-vaccines-gavi.html] (NYTimes) * Global vaccination rates drop, millions of children at risk [https://www.theguardian.com/society/2025/jun/24/children-global-vaccine-rates-fall-study-finds?CMP=oth_b-aplnews_d-1] (Guardian) * Autism rates [https://www.nytimes.com/2025/06/23/opinion/why-autism-rates-increased.html] have increased 60-fold, here’s why (NYTimes) * Deep mutational scanning of rabies virus glycoprotein [https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(25)00151-9?rss=yes] (Cell Host Micr) * Giant virus with proton gradient and partial TCA cycle [https://pubmed.ncbi.nlm.nih.gov/34556816/] (ISME J) * Why cells are powered by proton gradients [https://www.nature.com/scitable/topicpage/why-are-cells-powered-by-proton-gradients-14373960/] (Scitable) * Timestamps by Jolene [https://ramseylab.vercel.app/] Ramsey. Thanks! Weekly Picks Angela –  [https://www.cnn.com/2025/06/10/science/oort-cloud-unseen-structure-planetarium-discovery]27 new, exciting, and blobby species discovered in the Peruvian rainforest! [https://www.popsci.com/environment/new-species-amazon/] Brianne – Encounters in the Milky Way [https://www.amnh.org/exhibitions/space-show] Rich – Where to go for accurate, up-to-date vaccine information [https://wapo.st/4l3P1TE] Vincent – The members of RFK Jr.’s new vaccine committee have published little on vaccines [https://www.science.org/content/article/members-rfk-jr-s-new-vaccine-committee-have-published-little-vaccines] Listener Picks Charles – Vaccine Advice, Vandalized [http://science.org/content/blog-post/vaccine-advice-vandalized] Ken – Golden Goose Awards [https://www.goldengooseaward.org/awardees] Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are alarmed at how RFK is breaking his promise of not altering vaccine policies, and nonexistent data and studies are used by members of the ACIP to make changes to immunization practices in the absence of a CDC director, justification for not honoring the US commitment to GAVI and global public policies including support of routine childhood immunizations, placing millions of children at risk for the return of vaccine preventable diseases including polio outbreaks in Pappa New Guinea and increased circulation of wildtype type 1 poliovirus, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, approval of Merck’s anti-RSV mRNA monoclonal antibody, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, changes in COVID mRNA vaccine labeling and reframing of the science around the vaccine, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Jake Scott [https://med.stanford.edu/profiles/jake-scott#bio] (Stanford University) * Vaccine Randomized control trials [https://www.bradspellberg.com/vaccine-rcts] (Bradspellberg.com) * Vaccine RCT spreadsheet aims to show the data, dispel myths [https://www.cidrap.umn.edu/adult-non-flu-vaccines/vaccine-rct-spreadsheet-aims-show-data-dispel-myths-about-vaccines] about vaccines  (CIDRAP) * Vaccines [https://www.bradspellberg.com/vaccine-rcts]-rcts (Bradspellberg.com) * CDC’s upcoming vaccine advisory meeting set up to sow distrust [https://www.cidrap.umn.edu/vaccine-integrity-project/viewpoint-cdcs-upcoming-vaccine-advisory-meeting-set-sow-distrust] in vaccines (CIDRAP) * Next ACIP meeting [https://www.cdc.gov/acip/meetings/index.html] (CDC: ACIP) * June meeting: [https://www.cdc.gov/acip/downloads/agendas/Final-posted-2025-06-24-508.pdf] MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) (CDC: ACIP agenda) * Robert F Berman, PhD [https://health.ucdavis.edu/neurological-surgery/team/702/robert-berman---brain-injury-medicine---neurodevelopmental-disorders---neuroscience-research] (UC Davis Health: Department of Neurological Surgery) * Transparency = nonexistent data: CDC advisers appears to cite nonexistent study [https://www.cnn.com/2025/06/24/health/cdc-vaccine-adviser-thimerosal-presentation?cid=ios_app] to support claims about risk of vaccine preservative (CNN) * A C.D.C. Committee Just Voted Against Flu Shots [https://www.nytimes.com/2025/06/26/well/thimerosal-vaccines-risks.html?smid=nytcore-ios-share&referringSource=articleShare] With This Preservative. Is It Safe? (NY Times) * CDC vaccine advisory committee to review [https://www.statnews.com/2025/06/25/cdc-vaccines-advisory-committee-meeting-day-1/] long-approved immunizations (STAT News) * Newly appointed CDC vaccine advisory committee holds first meeting [https://www.cidrap.umn.edu/covid-19/newly-appointed-cdc-vaccine-advisory-committee-holds-first-meeting-stirs-more-controversy], stirs more controversy (CIDRAP) * FDA approves clesrovimab [https://www.contemporarypediatrics.com/view/fda-approves-clesrovimab-to-protect-infants-during-first-rsv-season] to protect infants during first RSV season (Contemporary Pediatrics) * ACIP updates [https://www.contemporarypediatrics.com/view/acip-updates-committee-votes-5-2-to-recommend-clesrovimab-to-protect-against-rsv]: Committee recommends clesrovimab for RSV, reaffirms routine influenza vaccination (Contemporary Pediatrics) * Susan Monarez [https://en.wikipedia.org/wiki/Susan_Monarez] (Wikipedia) * Robert F Kennedy Jr [https://en.wikipedia.org/wiki/Robert_F._Kennedy_Jr.] (Wikipedia) * Centers for Disease Control and Prevention [https://en.wikipedia.org/wiki/Centers_for_Disease_Control_and_Prevention] (Wikipedia) * Who is in charge [https://www.cdc.gov/about/leadership/] at the CDC (CDC: About CDC) * Do children REALLY [https://www.wsj.com/politics/policy/rfk-jr-s-new-vaccine-advisers-to-re-examine-shot-advice-for-children-ff08b8fd?mod=hp_lead_pos8] need to be vaccinated? (Wall Street Journal) * U.S. Adults’ Views [https://hsph.harvard.edu/wp-content/uploads/2025/06/HSPH-dBF_Vaccine-Survey-Topline-Data_June-2025.pdf] on Routine Childhood Vaccination (Harvard Opinion Research Program) * RFK Jr. declares US withdrawal from GAVI [https://www.youtube.com/watch?v=OMJEmFf8hXo] (YouTube) * Kennedy Withdraws U.S. Funding Pledge [https://www.nytimes.com/2025/06/25/health/kennedy-vaccines-gavi.html] to International Vaccine Agency (NY Times) * Millions of children [https://www.theguardian.com/society/2025/jun/24/children-global-vaccine-rates-fall-study-finds] at risk as global vaccine rates fall (Guardian) * Global, regional, and national trends in routine childhood vaccination [https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01037-2/abstract?utm_campaign=tlpr&utm_medium=email&_hsenc=p2ANqtz-_hyp3e19cd7QYY_2fUOqojx7Eymb2hzy9UiKCm8Cflc53XYrT6lnPdMqJgpPqcNHc5PwwvHUHu-1Nvvy2Aear0WWw8gRMShnUXJAtaowhV9pT1X8g&_hsmi=367755667&utm_content=367755667&utm_source=hs_email] coverage from 1980 to 2023 with forecasts to 2030 (LANCET) * Polio this week: 47 WPV1 positive [https://polioeradication.org/about-polio/polio-this-week/] environmental samples this week! (GPEI) * H5 bird flu [https://www.cdc.gov/bird-flu/situation-summary/index.html]: current situation (CDC: Avian Influenza) * Cambodia logs fifth death [https://www.cidrap.umn.edu/avian-influenza-bird-flu/cambodia-logs-fifth-death-h5n1-avian-flu-usda-weighs-poultry-vaccination] from H5N1 avian flu as USDA weighs poultry vaccination (CIDRAP) * Cambodia reports 6th H5N1 bird flu case [https://bnonews.com/index.php/2025/06/cambodia-reports-6th-h5n1-bird-flu-case-this-year/#google_vignette] this year(BNO News) * USDA develops potential plan [https://www.reuters.com/business/environment/usda-develops-potential-plan-vaccinate-poultry-bird-flu-2025-06-20/] to vaccinate poultry for bird flu (Reuters) * Wastewater [https://data.wastewaterscan.org/tracker/?charts=CuUJCidNZWFzbGVzLCBQYXJ0aWNpcGF0aW5nIFNpdGVzIE5hdGlvbndpZGUQASABQAFIAFIGZTEzNmMxUgYwN2NlZDdSBjE3MzU2MFIGMGZlYWRlUgZiNzIzYWVSBjEyZDJiNlIGYjllMzIyUgY3MWJhZTdSBjMxZWQzY1IGZDFhNGI4UgYxNGVmMDdSBmUwMGExYlIGOWY4OTgwUgY4MDA5ZTBSBmQzZmYxM1IGNmMwNTdiUgY1MDBmOWFSBjhiZWQ5MFIGY2E5MGI1UgY3YThiZTJSBjRlODhiM1IGZDEzYjI2UgZhM2E5MmRSBmE0ZTM5NFIGYmJjYTFhUgZkNThiODlSBjliODQ4MVIGMTM4MmY4UgY1Y2ZlZmRSBmZkZTZjY1IGZTFlMDNjUgY3M2U2MWNSBjY1N2VhNVIGNzJhN2IwUgYxNTAzMDhSBjkwNzcxM1IGNTllYzk0UgY0YTdiOTNSBjNhM2ZhMVIGOTRjMGM2UgZmYTJkNjNSBjY2YmM0NFIGYjk1ZjkzUgY5ODNmZjNSBjJkNmUxYlIGMDY1MjgyUgY4Nzk5NDZSBjk4YTI4ZFIGMDMyNWRkUgYxMDU2ZjBSBjc2NmU3N1IGMjZlYWUxUgZlOTA0ZWNSBmFmN2NkNVIGZWJiMDA0UgYwMmNjZGRSBjZmMDg5YlIGZDU5MmYxUgZkOWE4MTRSBmI0OWFhY1IGNjE5ODMxUgZhMGZiY2RSBjZmYTljN1IGMjU0ODE5UgZkZTExMDFSBjhhOWI0YlIGNmExMjRhUgYxOTkyZmNSBjY2MWU3MVIGYWUwM2Y3UgY3NTk0YzZSBjQ0OWZlMVIGNmE5Yzk0UgZjZGNlYWRSBjA1ZTI2Y1IGMjg5NGM5UgZiYzc5ZjlSBjY3YzM4MVIGNjVmOGJkUgZlOWU4N2VSBmY4NDdlNlIGNGZmNjNiUgZlZjBmZWNSBmVlYzJjMlIGNTM1NDRjUgY1NzlkYTNSBjc2Mzk0MVIGMTc2ODhlUgZhMTA4NmZSBjQ5ZTlmZlIGMTFhYWQyUgZhNDU1MjBSBjE0ZTIwM1IGNWM4NWVjUgYwMDE1YmFSBmI5YzAyZFIGNTQ3YzVkUgY4OTdhYmZSBjdkYWFlOFIGMzczNzAyUgZkZGU4OGZSBjMxOWFhNlIGZDk3NmY5UgY2YzliNmZSBjg0ZDQ4OVIGZWVhMzk4UgZiNTBjNjRSBmFkODZhOVIGY2QwODhiUgY0ODA1NTdSBmM4ZDM1N1IGMjYwZDFiUgY5NTE4MmNSBmMxZjMwMFIGMzE3NDU0UgY1M2YxMzBSBjk1Nzc5NFIGYTgyY2U5UgZjYjBlMWNSBmU1OTU4NVIGMzc0MzBhUgY0ZDlhZDFSBjA2NGFhY1IGMzdkY2IwUgYyZDQ1ZjJSBjFhOGIwZFIGZjQwNWI2UgZkZDM2ZmJSBmFkNjlkYlIGMDJmODU5UgY2YWM4ZWNSBjI2NGI4N1IGYzBjMmEyUgZjNTlmMmVSBjgzNjkzNlIGNmM0MDNmUgYxODkxZTBSBjNkNzk1M1IGMjRkN2YyUgZjMDg5ZWRSBjczM2YyNlIGNDA4YzAyUgYyZmE5MGNSBjI1ZmRlOVIGNWEzZmNlUgY0MzlmMjhSBjE5Y2M5ZVIGMWNiZDE1WgdNZVZfUm95eBOKAQY2NjhjMjI%3D&selectedChartId=668c22] for measles (WasterWater Scan) * Measles cases and outbreaks [https://www.cdc.gov/measles/data-research/index.html] (CDC Rubeola) * Weekly [https://health-infobase.canada.ca/measles-rubella/] measles and rubella monitoring (Government of Canada) * Measles vaccine recommendations from NYP (jpg [https://www.microbe.tv/twiv/wp-content/uploads/sites/2/measles_vax_rec_2.png]) * Measles [https://www.who.int/news-room/fact-sheets/detail/measles] (WHO) * Get the FACTS [https://www.health.ny.gov/diseases/communicable/measles/] about measles (NY State Department of Health) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] vaccine (CDC Measles (Rubeola)) * Presumptive evidence [file:///Users/Amy/Desktop/Measles%20(CDC%20Measles%20(Rubeola))] of measles immunity (CDC) * Contraindications and precautions [https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-13-measles.html#cdc_report_pub_study_section_9-contraindications-and-precautions-to-vaccination] to measles vaccination (CDC) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] (CDC: Measles Rubeola) * Adverse events associated with childhood vaccines [https://www.ncbi.nlm.nih.gov/books/NBK236284/#:~:text=The%20evidence%20favors%20acceptance%20of,in%20temporal%20relation%20to%20vaccination]: evidence bearing on causality (NLM) * Measles Vaccination: [https://www.idsociety.org/public-health/measles/know-the-facts/] Know the Facts(ISDA: Infectious Diseases Society of America) * Deaths following vaccination: what does the evidence show [https://www.sciencedirect.com/science/article/abs/pii/S0264410X15006556?via%3Dihub] (Vaccine) * Influenza: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * Respiratory virus activity [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] levels (CDC Respiratory Illnesses) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * FDA-CDC-DOD: [https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2026-us-influenza-season?mtm_source=25] 2025-2046 influenza vaccine composition (FDA) * RSV: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * RSV-Net [https://www.cdc.gov/rsv/php/surveillance/rsv-net.html]work (CDC Respiratory Syncytial virus Infection) * Novel Drug Approvals [https://www.fda.gov/drugs/novel-drug-approvals-fda/novel-drug-approvals-2025] for 2025 (FDA) * Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * COVID-19 deaths [https://covid.cdc.gov/covid-data-tracker/#maps_percent-covid-deaths] (CDC) * COVID-19 national and regional [https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html] trends (CDC) * COVID-19 variant tracker [https://covid.cdc.gov/covid-data-tracker/index.html#variant-proportions] (CDC) * SARS-CoV-2 genomes [https://nextstrain.org/ncov/gisaid/global/all-time?d=tree,frequencies&p=full&r=division&showBranchLabels=all&tl=none] galore (Nextstrain) * Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 [https://www.biorxiv.org/content/10.1101/2025.04.30.651462v1.full.pdf] (biRxiV) * Episode 184: Fool’s Gold: Reframing the Science [https://podcasts.apple.com/us/podcast/episode-184-fools-gold-reframing-the-science/id1504360345?i=1000710451230]…..reframing? (Apple Podcasts: Osterholm Update) * Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological [https://pubs.acs.org/doi/10.1021/acs.jproteome.5c00062?mtm_source=25] Metabolic Phenotypes (Journal of Proteome Research) * FDA COVID mRNA vaccine labeling [https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/fda-approves-required-updated-warning-labeling-mrna-covid-19-vaccines-regarding-myocarditis-and] update (FDA) * Where [https://www.pemgarda.com/hcp/infusion-center-locator/] to get pemgarda (Pemgarda) * EUA [https://investors.adagiotx.com/news-releases/news-release-details/invivyd-announces-fda-authorization-emergency-use-pemgardatm] for the pre-exposure prophylaxis of COVID-19 (INVIYD) * Infusion center [https://primeinfusions.com/locations/] (Prime Fusions) * CDC Quarantine [https://www.cdc.gov/respiratory-viruses/guidance/faqs.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/guidance/faq.html] guidelines (CDC) * NIH [https://www.ncbi.nlm.nih.gov/books/NBK570371/] COVID-19 treatment guidelines (NIH) * Drug interaction checker [https://covid19-druginteractions.org/checker] (University of Liverpool) * Infectious Disease Society guidelines [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground] for treatment and management (ID Society) * Molnupiravir safety [https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011] and efficacy (JMV) * Convalescent plasma recommendation for immunocompromised [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/] (ID Society) * What to do when sick with a respiratory virus [https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html] (CDC) * Managing healthcare staffing shortages [https://www.cdc.gov/covid/hcp/infection-control/mitigating-staff-shortages.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html] (CDC) * Steroids,dexamethasone [https://academic.oup.com/ofid/article/10/3/ofad105/7055978] at the right time (OFID) * Anticoagulation [https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19] guidelines (hematology.org) * Daniel Griffin’s evidence based [https://academic.oup.com/ofid/article/11/9/ofae462/7733485] medical practices for long COVID (OFID) * Long COVID hotline [https://www.columbiadoctors.org/health-library/article/long-covid/] (Columbia : Columbia University Irving Medical Center) * The answers: [https://longcovidtheanswers.com/] Long COVID * Stellate Ganglion Block for the Treatment of COVID-19−Induced Parosmia [https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2834979?mtm_source=25] (JAMA Otolaryngology-Head& Neck Surgery) * Reaching out to US house representative [https://www.house.gov/representatives/find-your-representative] * Letters read [https://www.microbe.tv/twiv/twiv-1230-letters/] on TWiV 1230 * Dr. Griffin’s COVID treatment summary (pdf [https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf]) * Timestamps by Jolene Ramsey [https://ramseylab.vercel.app/]. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Rich travels to Dubrovnik for the European Congress of Virology 2025 and Vincent joins via Zoom to speak with Stéphane Blanc, Vanda Juranić Lisnić, and Elisabeth Puchhammer-Stöckl about their work on plant viruses, cytomegalovirus, and Epstein-Barr virus. Hosts: Vincent Racaniello [https://en.wikipedia.org/wiki/Vincent_Racaniello] and Rich Condit [https://mgm.ufl.edu/profile/condit-rich/] Guests: Stéphane Blanc [https://umr-phim.cirad.fr/recherche/interactions-virus-vecteurs-plantes-virom/equipe-multi], Vanda Juranić Lisnić [http://capri.com.hr/about-vanda-j-lisnic], and Elisabeth Puchhammer-Stöckl [https://rpt.meduniwien.ac.at/en/research/research-groups/elisabeth-puchhammer-stoeckl-md/?cookies=CookieNotice%3D1%3Bcookie_matomo%3D1%3B] Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * Support science education  [https://www.microbe.tv/contribute]at MicrobeTV * Assembled plant viruses move through plants [https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011086] (PLoS Path) * Genome formula of multipartite virus [https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011973] (PLoS Path) * Immune surveillance of cytomegalovirus in tissues [https://pubmed.ncbi.nlm.nih.gov/39134803/] (Cell Mol Immunol) * Cytomegalovirus and NK cells [https://pubmed.ncbi.nlm.nih.gov/37828009/] (Nat Commun) * Epstein-Barr virus and multiple sclerosis [https://pubmed.ncbi.nlm.nih.gov/39484720/] (J Clin Inves) * Epstein-Barr virus and lymphoproliferative disease [https://pubmed.ncbi.nlm.nih.gov/39166902/] (Transplant) * Timestamps by Jolene [https://ramseylab.vercel.app/] Ramsey. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss in shock how RFK is breaking his promise of not altering vaccine policies by appointing new members of the ACIP, next ACIP meeting on guidelines for the COVID and RSV vaccines, circulation of “human insect viruses” including West Nile virus, and an outbreak of mpox on a cruise ship, and the ongoing measles outbreak before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, how to reduce the use of antibiotics for RSV and influenza infections in children, approval of the moderna RSV mRNA vaccine, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, contacting your federal government representative to stop the assault on science and biomedical research, and a shout out for the special episode of TWiV with David Tuller on long COVID and ME/CFS. Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * RFK Jr. is sabotaging the vaccine program. Here’s how to stop him [https://www.washingtonpost.com/opinions/2025/06/17/rfk-vaccines-acip-sabotage-states/] (Washington Post) * Innovaciones Alumbra [https://www.ialumbra.com/] (Alumbra Innovaciones) * John T Walton [https://en.wikipedia.org/wiki/John_T._Walton] (Wikiepedia) * Walmart [https://en.wikipedia.org/wiki/Walmart] (Wikipedia) * Sam Walton [https://en.wikipedia.org/wiki/Sam_Walton] (Wikipedia) * Condé Nast [https://en.wikipedia.org/wiki/Cond%C3%A9_Nast] (Wikipedia) * Christy Walton [https://en.wikipedia.org/wiki/Christy_Walton] (Wikipedia) * Vaccine Integrity Project ( [https://www.cidrap.umn.edu/vaccine-integrity-project] CIDRAP) * CIDRAP launches Vaccine Integrity Project [https://twin-cities.umn.edu/news-events/cidrap-launches-vaccine-integrity-project] (Twin Cities: University of Minnesota) * Next ACIP meeting [https://www.cdc.gov/acip/meetings/index.html] (CDC: ACIP) * June meeting: [https://www.cdc.gov/acip/downloads/agendas/draft-posted-2025-06-18.pdf] MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP)(CDC: ACIP agenda) * West Nile Virus and Other Nationally Notifiable Arboviral Diseases [https://www.cdc.gov/mmwr/volumes/74/wr/mm7421a1.htm?s_cid=mm7421a1_e&ACSTrackingID=USCDC_921-DM147703&ACSTrackingLabel=This%20Week%20in%20MMWR%3A%20Vol.%2074%2C%20June%2012%2C%202025&deliveryName=USCDC_921-DM147703] — United States, 2023 (CDC: MMWR) * Clade II Mpox [https://www.cdc.gov/mmwr/volumes/74/wr/mm7422a1.htm?s_cid=mm7422a1_w] Infections Among Cruise Ship Passengers and Crew Members — United States, 2024 (CDC: MMWR) * H5 bird flu [https://www.cdc.gov/bird-flu/situation-summary/index.html]: current situation (CDC: Avian Influenza) * Wastewater [https://data.wastewaterscan.org/tracker/?charts=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%3D&selectedChartId=668c22] for measles (WasterWater Scan) * Measles cases and outbreaks [https://www.cdc.gov/measles/data-research/index.html] (CDC Rubeola) * Weekly [https://health-infobase.canada.ca/measles-rubella/] measles and rubella monitoring (Government of Canada) * Measles [https://www.who.int/news-room/fact-sheets/detail/measles] (WHO) * Get the FACTS [https://www.health.ny.gov/diseases/communicable/measles/] about measles (NY State Department of Health) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola)) * Measles [https://www.cdc.gov/measles/index.html] vaccine (CDC Measles (Rubeola)) * Presumptive evidence [file:///Users/Amy/Desktop/Measles%20(CDC%20Measles%20(Rubeola))] of measles immunity (CDC) * Contraindications and precautions [https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-13-measles.html#cdc_report_pub_study_section_9-contraindications-and-precautions-to-vaccination] to measles vaccination (CDC) * Measles [https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html] (CDC Measles (Rubeola) * Measles vaccine recommendations from NYP (jpg [https://www.microbe.tv/twiv/wp-content/uploads/sites/2/measles_vax_rec_2.png]) * Adverse events associated with childhood vaccines [https://www.ncbi.nlm.nih.gov/books/NBK236284/#:~:text=The%20evidence%20favors%20acceptance%20of,in%20temporal%20relation%20to%20vaccination]: evidence bearing on causality (NLM) * Measles Vaccination: [https://www.idsociety.org/public-health/measles/know-the-facts/] Know the Facts (ISDA: Infectious Diseases Society of America) * Deaths following vaccination: what does the evidence show [https://www.sciencedirect.com/science/article/abs/pii/S0264410X15006556?via%3Dihub] (Vaccine) * Influenza: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * Respiratory virus activity [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] levels (CDC Respiratory Illnesses) * Weekly surveillance report: clift notes [https://www.cdc.gov/fluview/surveillance/2024-week-37.html] (CDC FluView) * Pediatric antibiotic use [https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiaf309/8158001?utm_source=advanceaccess&utm_campaign=jid&utm_medium=email#google_vignette] associated with respiratory syncytial virus and influenza in the United States, 2008-2018 (JID) * FDA-CDC-DOD: [https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2026-us-influenza-season?mtm_source=25] 2025-2046 influenza vaccine composition (FDA) * RSV: Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * US respiratory [https://www.cdc.gov/respiratory-viruses/data/activity-levels.html] virus activity (CDC Respiratory Illnesses) * RSV-Net [https://www.cdc.gov/rsv/php/surveillance/rsv-net.html]work (CDC Respiratory Syncytial virus Infection) * Novel Drug Approvals [https://www.fda.gov/drugs/novel-drug-approvals-fda/novel-drug-approvals-2025] for 2025 (FDA) * Effectiveness and impact of nirsevimab [https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00233-6/abstract?dgcid=raven_jbs_aip_email] in Chile during the first season of a national immunisation strategy against RSV (NIRSE-CL) (LANCET: Infectious Diseases) * Safety, Tolerability, and Immunogenicity ofmRNA-1345 [https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaf292/8156665] in Adults at Increased Risk for RSV Disease Aged 18 to 59 Years (CID) * Moderna Receives U.S. FDA Approval for RSV Vaccine, mRESVIA [https://investors.modernatx.com/news/news-details/2025/Moderna-Receives-U-S--FDA-Approval-for-RSV-Vaccine-mRESVIA-in-Adults-Aged-1859-at-Increased-Risk-for-RSV-Disease/default.aspx], in Adults Aged 18–59 at Increased Risk for RSV Disease (moderna) * Waste water scan for 11 pathogens [https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2] (WastewaterSCan) * COVID-19 deaths [https://covid.cdc.gov/covid-data-tracker/#maps_percent-covid-deaths] (CDC) * COVID-19 national and regional [https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html] trends (CDC) * Spatiotemporal Association of Coronavirus Disease 2019 Cases and Deaths With Exposure to Wildfire Particulate Matter [https://academic.oup.com/ofid/article/12/6/ofaf262/8160179?utm_source=advanceaccess&utm_campaign=ofid&utm_medium=email] in 2020 (OFID) * COVID-19 variant tracker [https://covid.cdc.gov/covid-data-tracker/index.html#variant-proportions] (CDC) * SARS-CoV-2 genomes [https://nextstrain.org/ncov/gisaid/global/all-time?d=tree,frequencies&p=full&r=division&showBranchLabels=all&tl=none] galore (Nextstrain) * Next ACIP meeting [https://www.cdc.gov/acip/meetings/index.html] (CDC: ACIP) * Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 [https://www.biorxiv.org/content/10.1101/2025.04.30.651462v1.full.pdf] (biRxiV) * Where [https://www.pemgarda.com/hcp/infusion-center-locator/] to get pemgarda (Pemgarda) * EUA [https://investors.adagiotx.com/news-releases/news-release-details/invivyd-announces-fda-authorization-emergency-use-pemgardatm] for the pre-exposure prophylaxis of COVID-19 (INVIYD) * Infusion center [https://primeinfusions.com/locations/] (Prime Fusions) * CDC Quarantine [https://www.cdc.gov/respiratory-viruses/guidance/faqs.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/guidance/faq.html] guidelines (CDC) * NIH [https://www.ncbi.nlm.nih.gov/books/NBK570371/] COVID-19 treatment guidelines (NIH) * Implementation of an online drug-drug interaction screener [https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofaf327/8160297] for the STRIVE ensitrelvir trial for COVID-19 (OFID) * Drug interaction checker [https://covid19-druginteractions.org/checker] (University of Liverpool) * Infectious Disease Society guidelines [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground] for treatment and management (ID Society) * Molnupiravir safety [https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011] and efficacy (JMV) * Convalescent plasma recommendation for immunocompromised [https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/] (ID Society) * What to do when sick with a respiratory virus [https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html] (CDC) * Managing healthcare staffing shortages [https://www.cdc.gov/covid/hcp/infection-control/mitigating-staff-shortages.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html] (CDC) * Steroids,dexamethasone [https://academic.oup.com/ofid/article/10/3/ofad105/7055978] at the right time (OFID) * Anticoagulation [https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19] guidelines (hematology.org) * Daniel Griffin’s evidence based [https://academic.oup.com/ofid/article/11/9/ofae462/7733485] medical practices for long COVID (OFID) * Long COVID hotline [https://www.columbiadoctors.org/health-library/article/long-covid/] (Columbia : Columbia University Irving Medical Center) * The answers: [https://longcovidtheanswers.com/] Long COVID * Long COVID and ME/CFS with David Tuller [https://www.microbe.tv/twiv/twiv-special-tuller/] (microbeTV) * Reaching out to US house representative [https://www.house.gov/representatives/find-your-representative] * Letters read [https://www.microbe.tv/twiv/twiv-1228-letters/] on TWiV 1228 * Dr. Griffin’s COVID treatment summary (pdf [https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf]) * Timestamps by Jolene Ramsey [https://ramseylab.vercel.app/]. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

David Tuller returns to TWiV to discuss RFK Jr. and the trashing of American public health, rituximab and ME/CFS, The Sick Times, the Cochrane Mess, a Norwegian Long Covid trial, effort preference and more. Host: Vincent Racaniello [http://en.wikipedia.org/wiki/Vincent_Racaniello] Guest: David Tuller [https://journalism.berkeley.edu/person/david_tuller/] Subscribe (free): Apple Podcasts [https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065], Google Podcasts [https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D], RSS [http://twiv.microbeworld.libsynpro.com/twiv], email [http://eepurl.com/Gcw59] Become a patron [https://www.microbe.tv/contribute] of TWiV! Links for this episode * MicrobeTV Discord Server [https://discord.gg/xA4JX7AeeU] * David Tuller [https://virology.ws/david-tuller-posts/] writes at virology blog * CFS, a long tangled tale [https://virology.ws/2011/11/23/chronic-fatigue-syndrome-and-the-cdc-a-long-tangled-tale/] (virology blog) * The Sick Times [https://thesicktimes.org/] * Norwegian Long COVID trial [https://virology.ws/2025/01/30/trial-by-error-norwegian-long-covid-rehab-trial-misrepresents-clinically-insignificant-findings-as-effective/] (virology blog) * Cochrane mess [https://virology.ws/2025/02/04/trial-by-error-my-article-on-the-cochrane-mess-in-the-sick-times/] (virology blog) * Timestamps by Jolene [https://ramseylab.vercel.app/]. Thanks! Intro music is by Ronald Jenkees [http://www.ronaldjenkees.com/] Send your virology questions and comments to twiv@microbe.tv Content on TWiV should not be taken as medical advice.