Dr. M’s Women and Children First Podcast #19 Repost – Dr. Alessio Fasano – Intestinal Permeability, Microbiome and MIS

Dr. M’s Women and Children First Podcast #19 Repost – Dr. Alessio Fasano – Intestinal Permeability, Microbiome and MIS

In this podcast repost, we rediscover the work of Pediatric Gastroenterologist Dr. Alessio Fasano from the Massachusettes General Hospital Department of Pediatric Gastroenterology. In this conversation, we discussed the research on Intestinal Permeability, Microbiomes and MIS, Multi Inflammatory Syndrome in Children . Dr. Fasano also directs the Mucosal Immunology and Biology Research Center and is associate chief for Basic, Clinical and Translational Research. Under his leadership, investigators are studying the molecular mechanisms of autoimmune disorders including celiac disease, and other-gluten-related disorders. He has been named visiting professor of pediatrics at Harvard Medical School. He authored the groundbreaking study in 2003 that established the rate of celiac disease at one in 133 Americans. Widely sought after by national and international media, Dr. Fasano has been featured in hundreds of interviews including outlets such as The New York Times, The Wall Street Journal; National Public Radio; CNN; Bloomberg News, and others. He recently co authored an excellent book with Susie Flaherty called Gut Feelings. I highly recommend you purchase and read this book. It is an encyclopedia of information regarding gut health, the microbiome and much more. Enjoy my conversation with Dr. Fasano, Dr. M

Dr. M’s SPA Newsletter Volume 16 Issue 21 – Saying No

The Healing Power of Saying No Why the path to health often begins with restraint! Every major faith tradition discovered something long before neuroscience or evolutionary biology could explain it. Growth often begins with restraint. During Lent, people give something up, not because chocolate, wine, or social media are inherently evil, but because saying no creates space. Space for awareness. Space for clarity. Space to notice how often our impulses quietly run the show. We need this space to rise above habit and find purpose. Science is slowly arriving at the same destination. The ability to delay gratification, to tolerate discomfort, to choose tomorrow over today is one of the strongest predictors of long-term health, happiness, and success. Restraint isn't deprivation. It's training. Training to: To survive. To procreate. To teach. To Be.... and a literature review. Enjoy, Dr. M

Dr. M’s Women and Children First Podcast #116: Russell Greenfield, MD – The Art of Listening

Welcome back to Dr. M's Women and Children First. One of the recurring themes on this podcast is that the future of medicine won't be discovered through faster-paced healthcare alone. It will be discovered by slowing down, listening more carefully, and embracing a patient-centered approach that seeks to understand the whole person—not just the disease. Ultimately, the future of medicine begins with a better question: How do we truly hear a patient's story so that we can better serve the person sitting in front of us? Today's guest has spent his entire career helping answer that question. Our conversation today centers on one of the most overlooked aspects of healing: why so many people struggle to begin the healing process in the first place—and more importantly, how we, as clinicians, parents, and patients, can help that process finally move forward. Dr. Russell Greenfield is a board-certified emergency medicine physician and a Diplomate of the American College of Lifestyle Medicine whose career has been dedicated to transforming healthcare from a disease-centered model into one focused on whole-person health. He has served as Medical Director of Integrative Medicine for major health systems, including Novant Health and the Weisiger Cancer Institute, held national leadership positions within the Veterans Health Administration's Whole Health Initiative, and continues to advise organizations across the country that are reimagining what healthcare can become. What makes Dr. Greenfield's journey especially unique is that he was one of the select physicians chosen to complete a residential fellowship under the mentorship of Dr. Andrew Weil at the University of Arizona—the birthplace of academic integrative medicine. At a time when very few physicians were willing to challenge the traditional boundaries of healthcare, Dr. Greenfield immersed himself in a model that recognized nutrition, movement, sleep, stress, relationships, purpose, and environment as fundamental pillars of health, while embracing the remarkable advances of modern medical science. For me, this conversation is especially meaningful because many of us in medicine are asking the same question: How do we move upstream? How do we stop waiting for chronic disease to develop and instead create the conditions where health can flourish? Today we'll explore the art of becoming an experienced listener in service of the patient before us. We'll discuss why curiosity often matters more than certainty, why healing frequently begins long before the prescription pad comes out, and how understanding a person's story can unlock opportunities that laboratory tests and imaging studies alone may never reveal. Whether you're a clinician, a parent, or simply someone searching for a deeper understanding of health, I think you'll come away from this conversation with a renewed appreciation for one of medicine's most powerful tools: listening. Enjoy, Dr. M

Dr. M’s SPA Newsletter Volume 16 Issue 20 – Healthcare Policy

Failing Them Why Are We? We are failing our children, the next generation. I have been spending an inordinate amount of time studying cellular biology and mitochondrial function in order to understand worsening disease trends. Thus, I want to revisit a landmark study that is one of the most comprehensive assessments of pediatric health ever conducted in the United States. Rather than examining a single disease or health outcome, Dr. Forrest and colleagues integrated data from multiple nationally representative surveys, mortality databases, and electronic health records encompassing millions of children to evaluate whether the health of American children has changed over the past 17 years. The answer was strikingly consistent: across virtually every major health domain, children in the United States are becoming less healthy. The investigators examined mortality, chronic physical and mental health conditions, obesity, functional status, sleep, puberty, physical symptoms, and emotional well-being between 2007 and 2023. Nearly every indicator worsened over time. "From 2007 to 2022, infants (<1 year old) were 1.78 and 1- to 19-year-old individuals were 1.80 times more likely to die in the US than in the OECD18. The 2 causes of death with the largest net difference between the US and OECD18 were prematurity and sudden unexpected infant death for infants 12 months or younger, and firearm-related incidents and motor vehicle crashes for 1- to 19-year-old individuals. From 2011 to 2023, the prevalence of 3- to 17-year-old individuals with a chronic condition rose from 39.9% to 45.7% within PEDSnet, and from 25.8% to 31.0% within the general population. Rates of obesity, early onset of menstruation, trouble sleeping, limitations in activity, physical symptoms, depressive symptoms, and loneliness all increased during the study period." (Forrest et. al. 2025)... and literature review. Enjoy, Dr. M

Dr. M’s SPA Newsletter Volume 16 Issue 19 – Pain

Pain Do we listen to its signal? Pain: Your Body's Built-In Warning System Pain is one of the body's oldest and most important protective mechanisms. It isn't your enemy. It is a messenger. Imagine walking barefoot across your living room and accidentally kicking the corner of the coffee table. The sharp pain that shoots through your toe isn't there to punish you, it is there to protect you. Within fractions of a second, nerves carry a signal to your brain, telling you that cells and tissue have been injured. Your body immediately encourages you to stop what you're doing. Protect the area and allow it to heal. This is acute pain, and it serves an essential purpose for both protection and survival. The problem arises when we stop thinking of pain as information and begin viewing it as something that simply needs to be eliminated. Over the past several decades, this mindset has increasingly influenced modern medicine. Around the turn of the century, pain was widely promoted as the "fifth vital sign," emphasizing the importance of recognizing and treating it. While this movement helped address the undertreatment of pain, it also contributed, in some settings, to an emphasis on suppressing pain rather than understanding why it existed in the first place. From an evolutionary perspective, pain is not a design flaw, it is a sophisticated communication system. It evolved to capture our attention, protect us from further injury, and encourage behaviors that promote healing. When we focus solely on silencing the signal without investigating its source, we risk missing the very message our bodies are trying to deliver, and deliver it will. Pain is information Every pain signal is your body's way of saying, "Something isn't quite right." Sometimes the cause is obvious like a sprained ankle, a cut, a burn, or a broken bone. Other times the message is much more subtle. .... Dr. M