Link Between Obesity and Inflammation with Dr. Isabelle Amigues, MD

Fertility, Weight, And Metabolic Health

We walk through how underweight, excess weight, and insulin resistance can change ovulation, fertility, and pregnancy risk long before a test turns positive. We also unpack PCOS basics, why some clinics enforce BMI cutoffs, and what safer preconception weight management can look like with your doctor.  • extremes of weight affecting ovulation and menstrual cycles  • RED-S and why under-fueling can stop periods  • PCOS prevalence and diagnostic criteria in plain language  • insulin resistance driving higher insulin and higher androgens  • why weight loss can be harder with high insulin  • small weight changes improving fertility potential in PCOS  • metformin and GLP-1 medications as medically supervised options before pregnancy  • fertility clinic BMI cutoffs, success metrics, and weight bias  • pregnancy complications linked with higher starting BMI, with risks possible at any size  • bariatric surgery timing and why waiting a year can matter  • anti-obesity medications not recommended in pregnancy or breastfeeding  • topiramate birth defect risk and the need for effective birth control  If you found this information helpful, please share with a friend, family member, or colleague.  Please subscribe and write a review.  ---------------------------------------------- Birth Control Option (YouTube) [https://youtu.be/lAMK9-4uqeU] Birth Control & GLP-1s (YouTube) [https://youtu.be/LB7Dm4qWc2I] 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

Food Aversions on GLP-1 Medications

One day eggs taste fine, and the next day the smell alone is a hard no. If you’re taking a GLP-1 medication and you’ve noticed sudden food aversions, you’re not imagining it and you’re not alone. We talk through what a true food aversion is, why it can feel so intense, and why it’s different from GI side effects like nausea or vomiting that need to be managed with your prescriber.  We also dig into the surprising ways GLP-1 therapy can change taste and food reward, from dulled flavors across sweet, salty, sour, bitter, and umami to the opposite experience where sweetness becomes almost too strong to tolerate. For many people, this leads to less interest in sugar-sweetened beverages and alcohol, fewer processed foods in the cart, and more whole foods day to day, which can support weight loss and better metabolic health. But we don’t gloss over the hard part: when aversions hit protein foods like meat or eggs, meeting your protein needs can feel suddenly complicated.  You’ll hear practical, patient-friendly strategies to work around protein aversions by rotating sources (fish, poultry, and other options), slowing titration when needed, and building a support team that includes a registered dietitian. We also discuss the emotional side of taste changes and how talk therapy can help if food has been a primary source of comfort or enjoyment. Finally, we explore the “pause” these medications can create and how it can help you break habits like nightly dessert or reflex snacking and eat with more intention.  If this helped you, share it with someone navigating GLP-1 food aversions, then subscribe and leave a review so more people can find trustworthy, evidence-based metabolic health guidance. GLP-1 Overview Video [https://youtu.be/J4LzMNEzyTs?si=B0CZ_qj25kK3uvP9] 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

Plant Based Nutrition With Dr. Shayla Toombs-Withers, DO

Having practiced a plant based diet for numerous years, Dr. Shayla Toombs-Withers incorporates her lifestyle into educating others how to improve and overcome their chronic diseases as a Family and Obesity Medicine Physician and Metabolic Health Coach. She founded Essence of Health Wellness Clinic & Coaching in Chattanooga, TN to help individuals heal their bodies and improve their health using her signature Mind Body Balance approach. Her basis for health are in line with two of her favorite quotes “an ounce of prevention is worth a pound of cure” and “let food be thy medicine.” Website: essenceofhealthwellnessclinic.com [https://www.essenceofhealthwellnessclinic.com ] IG: @essenceofhealthwellnessclinic [https://www.instagram.com/essenceofhealthwellnessclinic/?hl=en] TikTok: @drshayla [https://www.tiktok.com/@drshayla] YouTube: @EOHWCvideo [https://www.youtube.com/@EOHWCvideo] Podcast: Essence of Health Tea Time [https://rss.com/podcasts/teatimeeoh/] We talk with Dr. Shayla Toomes Withers about how plant-forward eating can support weight loss, blood sugar stability, and long-term metabolic health without an all-or-nothing mindset. We break down the most common plant-based pitfalls and share practical strategies for protein, travel, restaurants, and making changes that last.  • why fiber-rich whole plant foods improve fullness and help stabilize blood sugar  • using food sequencing to support portion control and post-meal glucose  • shifting the “meat and two sides” mindset toward a plant-forward plate  • clearing up protein fears with beans, tofu, tempeh, and oats  • avoiding the processed carb trap that stalls metabolic progress  • planning and self-advocacy when eating out or traveling  • using fruit and high-fiber choices to support gut health and GLP-1 constipation risk  • making it sustainable with small steps, journaling, and measurable goals  If you found this information helpful please share with a friend family member or colleague we need to do all we can to combat the dangerous misinformation that is out there. Please subscribe and write a review. This will help others find the podcast so they may also improve their metabolic health  👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

The Original Weight Loss Meds: Phentermine, Qsymia, and Contrave

GLP-1 medications are everywhere right now, but the “older” obesity medications never stopped helping real patients and they can still be the right tool when matched well. I walk through the three FDA-approved first-generation obesity management options and how I think about using them safely in modern obesity medicine, especially when cost, access, or specific symptoms like cravings are part of the story. We start with phentermine, the original FDA-approved weight loss medication, and get practical about what it actually does: appetite suppression, typical stimulant-like side effects, morning dosing, expected weight loss, and the key reasons it may be unsafe (like uncontrolled high blood pressure, certain heart conditions, glaucoma, or uncontrolled hyperthyroidism). Then we move into Qsymia, the phentermine plus topiramate combination, including why it tends to produce more weight loss, what to know about pricing, and the topiramate-specific risks like teratogenicity, kidney stones, fatigue, taste changes, and tingling sensations. Next, we dig into Contrave (bupropion plus naltrexone) and why it can be a great fit when food cravings, emotional eating, mood symptoms, or goals like cutting back on alcohol or smoking are front and center. I also explain the non-negotiable safety rules: no history of seizures, and no opioids of any kind, including products like kratom or 7OH, due to the risk of precipitated withdrawal. We close by talking strategy, including combining these oral options with GLP-1 therapy, using them for maintenance, and an honorable mention of metformin for insulin resistance and metabolic health. Subscribe, share this with someone who needs clear guidance, and leave a review so more people can find the podcast and improve their metabolic health. ------------------------------------------------- Qsymia discount program [https://qsymia.com/patient/multiple-ways-to-save] Contrave discount program [https://contrave.com/save/] 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]

Weight Gain During Menopause With Dr. Komal Patil-Sisodia, MD

Dr. Komal Patil-Sisodia is a triple board certified endocrinologist & women's health specialist based out of Washington state. Website: eastsidemm.com [https://www.eastsidemm.com/about] Instagram: @drpatilsisodia [https://www.instagram.com/drpatilsisodia/] TikTok: @dr-komal-patil-sisodia [https://www.tiktok.com/discover/dr-komal-patil-sisodia] Menopause symptom questionnaire: Greene Climacteric Scale  Menopause is a single moment on the calendar, but the real story is the long runway leading up to it and the way your whole body can change while your lab work still looks “fine.” We sit down with triple board certified endocrinologist and women’s health specialist Dr. Komal Patil-Sisodia to define menopause, perimenopause, and post-menopause in plain language, then connect the dots to what so many women actually feel: unpredictable cycles, shifting mood, sleep problems, brain fog, palpitations, vaginal dryness, recurrent UTIs, and even joint and muscle changes that can show up in midlife. We also tackle the elephant in the room: why hormone replacement therapy became so controversial after the Women’s Health Initiative and how the headlines shaped two decades of care. Instead of absolutes, we focus on nuance and shared decision making, including why symptom relief is the primary goal, how to think about risk, and why the route of estrogen matters when discussing blood clot concerns. Finally, we get practical about metabolic health and weight management. HRT is not a weight loss drug, but it may help body composition in some women and there’s emerging research on pairing menopause hormone therapy with GLP-1 medications like tirzepatide for improved outcomes. If you’re navigating PCOS, prediabetes, diabetes, or obesity in perimenopause, you’ll hear why individualized care beats blanket advice and how to advocate for the support you deserve. Subscribe, share this with a friend who needs it, and leave a review so more women can find evidence-based menopause and metabolic health guidance. 👩🏼‍⚕️ Live in Missouri? Want to be my patient? Telehealth clinic: https://missourimetabolichealth.com [https://missourimetabolichealth.com/about-telehealth-clinic] 🥑 Have questions you want answered on the podcast? Email support@missourimetabolichealth.com ✨Freebies✨ Anti-Obesity Medication Options [https://drlindsayogle.kit.com/medications] How To Prevent Diabetes [https://drlindsayogle.ck.page/diabetes] Healthy Habits Workbook [https://drlindsayogle.kit.com/habits] Preventative Health Checklist [https://drlindsayogle.ck.page/1eecd5e72f] 🤗 Socials: Instagram: https://www.instagram.com/dr.lindsayogle/ [https://www.instagram.com/dr.lindsayogle/] TikTok: https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1 [https://www.tiktok.com/@dr..lindsay.ogle?_t=8prC4VUQZ5i&_r=1] YouTube: https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg [https://www.youtube.com/channel/UCMV0X6U0JLZgRMiNwGtmpeg]