WTR Healthcare Happenings

NurExone Biologic (NRX): The Inhibitor of the Inhibitor: How Nurexone's ExoPTEN Is Designed to Restart Nerve Regeneration

In this episode of Healthcare Happenings, Robert Sassoon, WTR healthcare equity analyst, joins host Tim Gerdeman to discuss his initiation of coverage on NurExone Biologic (TSXV: NRX / OTCQB: NRXBF), a preclinical biopharma company advancing a novel exosome platform targeting CNS regeneration. Sassoon walks through the science behind exosome therapeutics, NurExone's differentiated ExoTherapy platform and lead asset ExoP10, which combines a natural exosome carrier with an RNA payload designed to silence the P10 gene and unlock nerve regeneration in acute spinal cord and optic nerve injury. The conversation also covers the company's vertical integration strategy through its Exotop subsidiary and U.S. master cell bank, the LOI with Florida-based BioXTech for GMP manufacturing capacity, and the key milestones investors should track, including IND submission, compassionate use access, first commercial exosome revenue, and a potential U.S. mainboard listing.

PharmAla Biotech (MDMA): Two Transactions, One Strategy: Unlocking Pipeline Value Through Structured Partnerships

In this episode of Healthcare Happenings, Nick Kadysh, Founding CEO and President of PharmAla Biotech (CSE: MDMA / OTCQB: MDXXF), joins host Tim Gerdeman and WTR healthcare analyst Robert Sassoon to discuss two recently announced transactions. The first is the formation of Restora Neuroscience, a special purpose vehicle created to advance APA01, a non-controlled neurology molecule, through a preclinical partnership with Datiba. The second is a term sheet with Jupiter Neurosciences for the exclusive U.S. licensing of ALA-002, PharmAla's next-generation MDMA therapeutic, in a deal valued at over $100 million in potential milestones and royalties. The conversation covers deal structure, partner selection, key investor milestones across both transactions, and how this partnership-driven model allows PharmAla to advance its pipeline while maintaining its position as a leading global supplier of clinical-grade MDMA.

Solvonis Therapeutics (SVNS): CSO Professor David Nutt on Solvonis' Approach to Resetting the Addicted Brain

In this special episode of the WTR Healthcare Happenings podcast, the second in a two-part series, Professor David Nutt, Chief Science Officer of Solvonis Therapeutics (LSE: SVNS), talks to host Tim Gerdeman and WTR analyst Robert Sassoon about addiction and why he believes Solvonis' novel approach offers potentially better solutions than are currently available. The discussion also covers persistently low AUD treatment penetration, the favorable UK regulatory and reimbursement outlook versus US payer dynamics, how ketamine compares with emerging GLP-1 and psilocybin approaches, and the advantages of Solvonis' AI-enabled drug discovery platform. Finally, Nutt shares his thoughts on where the US federal addiction-research community actually is on psychedelic-assisted treatment for AUD and stimulant use disorder, following his recent presentation at the NIH ( National Institutes of Health) CRAN (Collaborative Research on Addiction) joint council as the sole external speaker on psychedelic therapy for addictions.

Solvonis Therapeutics (SVNS): Rewriting the Standard of Care for Severe Alcohol Use Disorder

In this special episode of Healthcare Happenings, the first in a two‑part series, Anthony Tennyson, CEO of Solvonis Therapeutics (LSE: SVNS), joins host Tim Gerdeman and WTR analyst Robert Sassoon to discuss the company’s strategy in addiction and psychiatry — a field with significant unmet need and limited effective treatment options. Anthony walks through SVN‑001, a ketamine‑based therapy for severe alcohol use disorder now in Phase 3 in the UK, and SVN‑002, a U.S.-focused program targeting the much larger moderate‑to‑severe alcohol use disorder market. He also explains why Solvonis may not yet be fully recognized compared to its U.S.-listed peers.  Stay tuned for Part 2 next week with Professor David Nutt, Chief Scientific Officer of Solvonis, who unpacks the neuroscience behind SVN‑001, the search for a better MDMA, and where psychedelic‑assisted addiction therapy is headed.

PetVivo Holdings (PETV): The Trifecta: Regenerative Science, AI-Enabled Vet Care, and Human Translation

In this episode of Healthcare Happenings, John Lai, CEO of PetVivo Holdings (PETV), joins host Tim Gerdeman and WTR analyst Robert Sassoon to discuss the company's regenerative medicine platform for companion animals. The conversation covers PetVivo's product suite led by Spryng, its cartilage-mimicking protein particle matrix; the off-the-shelf Precise PRP product; and a BioPiezo collaboration with the University of Connecticut that pairs Spryng with nanofiber technology to drive cartilage regeneration with potential translation to human medicine. Lai also previews the launch of PetVivo.ai, an agentic AI platform for veterinary practices, and outlines the company's pathway toward cash-flow breakeven.