EPISODE 100: The Future of Personalized Medicine Is Already Here | Dr. Anil Bajnath on Multiomics, Longevity & the Blueprint Your Doctor Never Ordered

EPISODE 100: The Future of Personalized Medicine Is Already Here | Dr. Anil Bajnath on Multiomics, Longevity & the Blueprint Your Doctor Never Ordered

Episode 100. Hard to Kill in Midlife. One hundred conversations in — and for this one, I wanted someone operating at the absolute frontier of what personalized health can look like.Dr. Anil Bajnath MD — author of The Longevity Equation, founder of the Institute for Human Optimization, and founder of the American Board of Precision Medicine — joins the show to break down why your standard blood panel is telling your doctor almost nothing, what deep molecular phenotyping actually reveals, and why the future of healthcare is an N of 1 protocol built from your specific genome, microbiome, metabolome, and environmental toxin load.For midlife athletes, biohackers, BJJ over 40 practitioners, and anyone serious about hard to kill in midlife longevity — this is the most technically advanced health conversation I have had in 100 episodes. And we still found time to talk about jiu-jitsu.Topics covered:→ How a 16-year-old at Whole Foods in Plantation, Florida started a precision medicine career→ Deep molecular phenotyping — what multiomics actually means and why it matters→ Genomics, transcriptomics, proteomics, metabolomics, microbiome, exposomics — the full stack→ The digital twin: what your molecular portrait reveals that no symptom can→ Pharmacogenomics — why your prescribed medication might be wrong for your genome→ The homocysteine debate: why population meta-analyses cannot answer individual questions→ Why the microbiome is the innocent bystander to every other stressor in the system→ Exposomics — heavy metals, organophosphates, phthalates, mycotoxins, and what to do→ The grounding researcher with the highest naturally occurring testosterone over 60 ever measured→ The lymphatic system, Flowpresso, and why protein reduction matters more than compression→ Water — reverse osmosis, remineralization, deuterium, and what tap water actually contains→ Mold and mycotoxins — the hidden burden nobody's asking about→ Why insurance companies deny the tests that would prevent the conditions they pay to treat→ Function Health, direct-to-consumer testing, and the democratization of precision labs→ AI in medicine — why AI slop upstream causes deleterious downstream consequences→ The American Board of Precision Medicine and why this needs to be the standard of care→ Self-experimentation guardrails — where it's useful and where it gets dangerous→ George Pereira, American Top Team Davie, Vagner Rocha — the South Florida jiu-jitsu connection→ 14 months off the mats and counting — what brought him here and what he's building toward━━━━━━━━━━━━━━━━━━━━━━🔗 Find Dr. Anil Bajnath:Instagram: @dranilbajnathInstitute for Human Optimization: @instituteforhumanoptimization · ifho.orgAmerican Board of Precision Medicine: abopm.orgWebsite: anilbajnath.comThe Longevity Equation — available now🔗 Lineage Provisions — Official Podcast Partner:15% off with code JOSHBUTTON at lineageprovisions.comOr grab the link in bio🔗 Find Josh:Instagram: @thatjiujiteiro | @stopkillingtheplantsWebsite: joshbutton.com Anil Bajnath, Institute for Human Optimization, American Board of Precision Medicine, The Longevity Equation, precision medicine, multiomics, deep molecular phenotyping, digital twin health, genomics, microbiome, exposomics, pharmacogenomics, lymphatic drainage, grounding earthing, water filtration, environmental toxins, mycotoxins, hard to kill in midlife, hard to kill, BJJ over 40, BJJ after 40, midlife performance, longevity, biohacking, training after 40, midlife combat athlete, episode 100, josh button podcast, that jiujiteiro, stop killing the plants, lineage provisions, MTHFR methylation, functional medicine, personalized medicine

The Food Industry Doesn't Want You to Know This | Niklas Gustafson on Ancestral Nutrition, Seed Oils, Oxalates & Raw Dairy EP99

He has been a celiac since birth. Nearly didn't survive infancy. Was experimenting in his grandmothers' kitchens at five years old because there was nothing safe on the supermarket shelf. Now 56 — 13 Ironman triathlons completed, six kids, zero alcohol for four years, and a food company that makes real food in a market that resists it.Niklas Gustafson — co-founder of Natruly, host of Hungry for Change, and one of the clearest voices in the ancestral nutrition space — joins Josh Button on the Stop Killing the Plants episode that covers everything: why the spinach superfood myth is built on ignorance of oxalates, what plant milk actually contains and why it's the biggest food scam of the last decade, why raw dairy is treated as contraband while alcohol is freely sold, and what four years without alcohol actually changed.For anyone serious about ancestral nutrition, real food, and hard to kill in midlife living — this one is foundational.Topics covered:→ Celiac from birth in 1970s Sweden — and what that education produced→ The five pillars: nutrition, exercise, sleep, sun, and social connection→ Cutting refined sugar at 40 — the first domino that changed everything→ Paleo, keto, carnivore, animal-based — the full 16-year self-experiment→ Why spinach is not a superfood — the oxalate problem nobody teaches→ Plant milk: what emulsifiers, enzymatic sugar conversion, and the Oatly scam actually mean→ Seed oils in everything — including the Nutella you grew up eating→ The Natruly 43% hazelnut spread — what a real version of that product looks like→ Raw dairy as contraband — why you can buy unlimited alcohol but not unpasteurized milk→ Fake meat and pea protein companies — why they're crashing and why that's good news→ Baby formula: sugar and seed oils from month one→ Let the kid choose from whole foods — and trust what they choose→ Natural testosterone support — sun, lifting, sleep, no alcohol, no seed oils→ GLP-1 drugs: the industry that profits from your insecurity→ Borrowing happiness from tomorrow — four years without alcohol and what changed→ The dinner table conversation that drops in quality after the second bottle→ RFK Jr., MAHA, and why the mainstream media won't say anything good about him→ GMO crop labeling changes in the EU — what's being slipped through under the radar→ One word: Truth━━━━━━━━━━━━━━━━━━━━━━🔗 Find Niklas Gustafson:Instagram: @NiklasGustafsonNatruly: @Natruly_Int · natruly.comPodcast: Hungry for Change🔗 Lineage Provisions — Official Podcast Partner:15% off with code JOSHBUTTON at lineageprovisions.comOr grab the link in bio🔗 Find Josh:Instagram: @thatjiujiteiro | @stopkillingtheplants | @IamJoshButtonWebsite: joshbutton.com

The Strength Training Mistake BJJ Over 40 Athletes Keep Making — Dr. Lyneil Mitchell on Isokinetics, Maladaptation & Midlife Jiu-Jitsu EP98

If you're training BJJ over 40 and still treating weight as your primary measure of strength progress — this conversation will change how you think about every session.Dr. Lyneil Mitchell DPT returns for part two to break down why most strength training for midlife BJJ athletes and combat sports practitioners is building maladaptation instead of performance, why isokinetics represent the highest return on investment for BJJ after 40, and why the nervous system is silently patterning the wrong thing in almost every gym in the world.For midlife jiu-jitsu practitioners, midlife combat athletes, and anyone doing BJJ recovery over 40 — this is the episode that explains what the research actually says about training after 40.Topics covered:→ What happened when Josh applied the strong angle question in live training — it works in chaos→ Two guys in the strong angle at the same time — why high-level matches look like standoffs→ Why weight always overloads your weakest angle first — and what your connective tissue is paying→ Isokinetics vs. weightlifting for BJJ over 40 — when the transition has to happen→ Accommodating resistance — why it sounds soft and why it's not→ Diminishing returns on connective tissue — the timeline problem nobody explains→ The breathing test applied to the weight room — the simplest diagnostic you have→ The Hebbian principle — neurons that fire together wire together and you're patterning right now→ The pinky grip example — how a small mechanical habit silently destroys the chain above it→ Irradiation — the facilitation cascade that runs through your entire kinetic chain→ Isometric overuse — why training the stuck position makes you worse at reacting→ Why training your weak side is the most direct path to improving your strong side→ Integrity under demand — a new definition of fitness for midlife athletes→ The three rules Lyneil gives everyone from his son to professional athletes→ Professional sports, cortisone injections, and the dark side of return-to-play medicine→ OJ McDuffie, turf toe, and the legal battle over how it was managed→ The 49ers substation, the Nike shoe that ended careers, and what gets swept under the rug→ Efficiency — the one word that contains the entire framework━━━━━━━━━━━━━━━━━━━━━━🔗 Find Dr. Lyneil Mitchell:Instagram: @drlyneilWebsite & Free Assessment: thestrongangle.comThe Strong Angle Way — Amazon🔗 Lineage Provisions — Official Podcast Partner:15% off with code JOSHBUTTON at lineageprovisions.comOr grab the link in bio🔗 Find Josh:Instagram: @thatjiujiteiro | @stopkillingtheplantsWebsite: joshbutton.com━━━━━━━━━━━━━━━━━━━━━━Lyneil Mitchell, The Strong Angle Way, BJJ over 40, BJJ after 40, midlife jiu-jitsu, midlife combat athlete, BJJ recovery over 40, training after 40, midlife BJJ, midlife grappler, staying on the mats, isokinetics, accommodating resistance, Hebbian principle, neurological strength training, strong angle, weak angle, integrity under demand, maladaptation, non-contact injury prevention, midlife athlete, martial arts over 40, BJJ longevity, staying dangerous after 40, Josh Button podcast, that jiujiteiro, stop killing the plants, hard to kill, ep98, Quintin Torres, Marinovich Systems, Lineage Provisions

The Biomechanics Blind Spot Ending Midlife Athletic Careers | Dr. Lyneil Mitchell on the Strong Angle, BJJ Injury Prevention & Neuromuscular Rehab EP97

Most midlife athletes aren't getting hurt because they're training too hard. They're getting hurt because nobody taught them the one question that determines whether a training session builds you or slowly destroys you.Dr. Lyneil Mitchell — two-time Division II All-American wrestler, Doctor of Physical Therapy, Marinovich Systems practitioner, and author of The Strong Angle Way — joins Josh Button to break down why the dominant-side game you've been building for years is quietly capping your performance, what the University of Cincinnati ACL research group taught him about how every joint in the body actually works, and the single evaluative question that changes everything.Topics covered:→ The turf toe that didn't heal — nine cortisone injections, two competitive years on one foot, what finally worked→ What the strong angle actually is — and why it's a felt sense, not a position→ Why weight always overloads your weakest angle first — and what that does to your kinetic chain over time→ The crossover infection — how a foot injury reorganizes every joint above it for years→ Hines Ward as a non-surgical ACL coper — what his nervous system could do that most can't→ The bilateral coordination blind spot — why training your weak side improves your strong side→ Ambikinesis — the four-sided body awareness masters have that most athletes never develop→ The breathing diagnostic — the fastest way to know if you're in the strong angle right now→ How BJJ framing injuries are actually scapular failures nobody is catching→ The return-to-sport principle that should govern all training, not just rehab→ Self-control vs. self-mastery — and why your white belt brain can't see the black belt pattern→ The basics before the exotic — why innovation only works on top of mastery━━━━━━━━━━━━━━━━━━━━━━🔗 Find Dr. Lyneil Mitchell:Instagram: @drlyneilWebsite & Free Assessment: thestrongangleway.comThe Strong Angle Way — Amazon🔗 Lineage Provisions — Official Podcast Partner:15% off with code JOSHBUTTON at lineageprovisions.comOr grab the link in bio🔗 Find Josh:Instagram: @thatjiujiteiro | @stopkillingtheplantsWebsite: joshbutton.com━━━━━━━━━━━━━━━━━━━━━━TIMESTAMPS0:00 — Intro: Who is Dr. Lyneil Mitchell?0:43 — Two-time All-American wrestler, turf toe, nine cortisone injections2:59 — From wrestling to physical therapy — the six-year path4:17 — ACL research at University of Cincinnati, non-surgical copers6:21 — Marinovich Systems — how Josh Rafferty and BJ Penn's barefoot training connected7:14 — Did Marinovich Systems fix the turf toe?9:05 — Traditional rehab vs. neuromuscular emphasis — the key difference9:45 — Non-surgical copers — Hines Ward and joint centration13:00 — Self-experimentation and the code behind the strong angle16:35 — The strong angle and weak angle defined19:45 — Why the blueprint nobody gives midlife jiu-jitsu athletes matters20:41 — The Strong Angle Way book — self-control vs. self-mastery22:30 — Mastery and leadership — how they develop whether you aim for them or not26:30 — Wrestling vs. jiu-jitsu — what each sport selects for28:44 — Biomechanics for grapplers — why it's the most neglected area30:00 — The dominant-side problem — one-sided jiu-jitsu and the hip it's building33:40 — The framing failure — when two identical-looking movements are completely different38:00 — Bilateral coordination, the crossover effect, and training the weak side40:00 — Stability training vs. proactive movement — where the crossover fails44:12 — Reactive vs. proactive stabilization — what the Wobbler trains51:30 — The SuperCAT, rate of force production, and Mike Maddox's isokinetic machine56:06 — Liability, the physical therapy profession, and self-efficacy01:04 — Part two teased — much more to cover01:04 — Three words: The Strong Angle Lyneil Mitchell, The Strong Angle Way, strong angle biomechanics, BJJ injury prevention, sports rehab, physical therapy for athletes

Navy Diver, BJJ Black Belt at 40+: How William Dorman Built a Game Nobody Can Touch | EP96

He started jiu-jitsu in 2006 when a 120-pound woman in a Hawaiian shopping center handed him his wrestling credentials back. He went home and trained harder. Two decades later, he's a BJJ black belt under Gustavo Machado, a BJJ Globetrotters international coach, a Navy diver veteran, and one of the most interesting conversations I've had on this show.William Dorman — founder of Blue Ring Solutions, We Defy Foundation ambassador, and BJJ Fanatics instructional creator — joins Josh Button to talk top pressure passing, staying on the mats past 40 with a body that needs replacing in multiple places, building cold plunges in Afghanistan, playing didgeridoo for his garden, and why he believes jiu-jitsu is the best thing for humanity.Topics covered:→ How Steve Hordinski and a Kailua shopping center changed everything in 2006→ Getting destroyed as a wrestler and going all in — the split that determines who stays→ The over-under top pressure system that nobody escapes — and why it protects his feet→ Half guard both ways: Gustavo Machado, Roberto Gordo lineage, and the offensive half guard game→ Gi technique in no-gi: the lasso sweep that works better than anyone expects→ The funnel system: three options, all accounted for→ Cold plunges in Afghanistan — the chest freezer setup, chemical testing, wood stairs→ Yoga since 2007, breath work for Aconcagua, HRV training with Warrior Wellness Solutions→ Gardening as therapy: grounding, barefoot in dirt, didgeridoo for the plants→ Plant medicine: ayahuasca in Brazil, Rising Ridge retreat, integration practices→ Why suffering is the prerequisite for growth — and what jiu-jitsu does that the military couldn't→ We Defy Foundation: jiu-jitsu for combat-disabled veterans, $80K raised at Renzo's→ What keeps midlife men on the mats — and why culture beats technique every time→ The 76-year-old judo guy who shows up every morning and what he represents→ "When you rest, you rust" — the 90-year-old on the plane and how to live by it→ One word: Positivity — and the fighter pilot who said "it is what it is"━━━━━━━━━━━━━━━━━━━━━━🔗 Find William Dorman:Instagram: @williamdormanbjjBJJ Fanatics (Pressure Passing instructional): bjjfanatics.comBJJ Globetrotters YouTube: youtube.com/bjjglobetrottersWe Defy Foundation: wedefyfoundation.org🔗 Lineage Provisions — Official Podcast Partner:15% off with code JOSHBUTTON at lineageprovisions.comOr grab the link in bio🔗 Find Josh:Instagram: @thatjiujiteiro | @stopkillingtheplants | @IamJoshButtonWebsite: joshbutton.com William Dorman, Blue Ring Solutions, We Defy Foundation, BJJ Globetrotters, navy diver jiu-jitsu, BJJ black belt over 40, Gustavo Machado BJJ, top pressure passing BJJ, half guard jiu-jitsu, midlife BJJ, BJJ over 40, staying on the mats, veteran jiu-jitsu, cold plunge recovery, yoga for BJJ, breathwork HRV, grounding earthing, plant medicine veterans, ayahuasca veterans, jiu-jitsu for veterans, Josh Button podcast, that jiujiteiro, stop killing the plants, hard to kill, ep96, suffering and growth, positivity mindset, BJJ Fanatics, pressure passing BJJ, when you rest you rust