Hyperfixed

When Marlena's cat was diagnosed with a terminal disease, she found herself seeking help not from a vet, but a series of websites and Facebook groups. The first in a three-part series. Support independent journalism by becoming a part of our premium user community. Join the discord, get access to exclusive merch (soon), and much much more.  https://www.hyperfixedpod.com/join [https://www.hyperfixedpod.com/join] LINKS: GS treatment available in pharmacies: https://bestfriends.org/sites/default/files/2024-11/Network_09%20Webinar_FIP%20Treatment_US-Pharmacy-FIP-Treatment-Options.pdf [https://bestfriends.org/sites/default/files/2024-11/Network_09%20Webinar_FIP%20Treatment_US-Pharmacy-FIP-Treatment-Options.pdf] Dr. Pedersen's 2019 paper [https://pubmed.ncbi.nlm.nih.gov/30755068/] FIP Warriors Facebook Group [https://www.facebook.com/groups/fipwarriorsoriginal/] Gilead's statement:  Since Gilead identified GS-441524 as a potential treatment for cats with feline infectious peritonitis (FIP), we made it available to institutions with the expertise to advance medicines for veterinary use. This is why we shared GS-441524 with UC Davis to research its impact on FIP. GS-441524 is an intermediate in the synthesis of remdesivir, an approved treatment for COVID-19. Gilead’s supply of GS-441524 was and continues to be used to manufacture remdesivir to meet the demands of COVID-19. Today, remdesivir has been made available to more than 14.5 million patients around the world, including more than 8.1 million in low- and lower-middle income countries. In parallel, Gilead has made progress in studies identifying prodrugs of GS-441524 with improved oral bioavailability that could be further investigated as a therapeutic for FIP in cats. Discussions with suitable veterinary specialty companies are ongoing, but to-date we have not identified an appropriate partner. Gilead supports finding a solution for FIP at the earliest opportunity. Learn about your ad choices: dovetail.prx.org/ad-choices [https://dovetail.prx.org/ad-choices]

This week, we're running an episode of one of our favorite shows, The Dream [https://podcasts.apple.com/us/podcast/the-dream/id1435743296], hosted by Jane Marie. At the top of this episode I talk to Jane Marie about her show, and the fact that we went to the same high school and didn't know each other (true story!)  THIS EPISODE: This past year Charlotte Isenberg, a once-popular teen anti-abortion activist, found herself switching sides in this national debate. What happened to her next is unprecedented and a warning for parents and kids alike. Find Charlotte on Tik Tok here: LINKS: Follow Charlotte on TikTok Here [https://www.tiktok.com/@blueridgejewess] Listen to The Dream iTunes [https://podcasts.apple.com/us/podcast/the-dream/id1435743296] Spotify [https://open.spotify.com/show/69SbOSdWtOYpJArpX6KczL] PocketCasts [https://pocketcasts.com/podcasts/1a177af0-9754-0136-7b93-27f978dac4db] Follow Jane Marie on: Instagram [https://www.instagram.com/seejanemarie/?hl=en] BlueSky [https://bsky.app/profile/seejanemarie.bsky.social] TikTok [https://www.tiktok.com/discover/seejanemarie] Learn about your ad choices: dovetail.prx.org/ad-choices [https://dovetail.prx.org/ad-choices]

Special unlocked bonus ep! And a note at the top from Alex! Please support Hyperfixed by becoming a premium member to hear more episodes like this one and get many more perks besides!  https://www.hyperfixedpod.com/ [https://www.hyperfixedpod.com/] Astrid, the star of the episode Little by Little, [https://www.hyperfixedpod.com/listen/hyperfixed/little-by-little] talks about recreating an impossible instrument from an iconic episode of Star Trek in real life. LINKS: The Aldean Instrument [https://youtu.be/1RWoT3XZKwM?si=wA99a3gYWAp2TCUR] Astrid's Keynote at the Audio Developer Conference [https://youtu.be/c7YFLqPmc5E?si=dhsfVvxGN_G0Z0mv] Commander Riker Sits Down [https://www.youtube.com/watch?v=lVIGhYMwRgs] Learn about your ad choices: dovetail.prx.org/ad-choices [https://dovetail.prx.org/ad-choices]

A preview of what you're missing if you aren't subscribed to Hyperfixed Premium! A story about a wonderful mother and daughter and their hunt for the perfect cake. Even if you aren't planning on signing up, please listen. You’ll love it, I promise. To listen to the entire interview: https://www.hyperfixedpod.com/join [https://www.hyperfixedpod.com/join] Learn about your ad choices: dovetail.prx.org/ad-choices [https://dovetail.prx.org/ad-choices]

Ali's house burnt down in this year's Los Angeles fires and took her entire life with it. Well almost her entire life. And she wants our help to make sure she doesn't lose one of the few precious things that survived the fire. Becoming a premium member helps Hyperfixed continue to exist! Sign up for bonus episodes, access to our discord forthcoming exclusive merchandise, and more! https://www.hyperfixedpod.com/join [https://www.hyperfixedpod.com/join] Learn about your ad choices: dovetail.prx.org/ad-choices [https://dovetail.prx.org/ad-choices]