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The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.
305 episodios
Most replayed moment: Coffee vs Matcha | Andrew Kojima & Prof Tim Spector
Today, we’re diving into some popular drinks. Coffee has long been the undisputed champion of hot beverages. Its bitter taste is an essential part of most people's morning. However, there’s a new kid on the block. You might have seen its distinctive green hue cropping up in cafés, supermarkets or even TikTok. I am of course talking about matcha. So how do coffee and matcha compare? Do they work differently in the body? And is one better for your long-term health? I’m joined by matcha expert Andrew Kojima and Professor Tim Spector to explore the science behind our daily pick-me-ups - and discover whether we should be switching sides. 🌱 Try our science-backed and tasty wholefood supplement Daily 30+ [https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=d30] Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE [https://zoe.com/buymembership?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=BAU] Follow ZOE on Instagram [https://www.instagram.com/zoe/]. 📚Books by our ZOE Scientists The Food For Life Cookbook [https://amzn.to/4amfIMX] Every Body Should Know This by Dr Federica Amati [https://amzn.to/4blJsLg] Food For Life by Prof. Tim Spector [https://amzn.to/4amZinu] Ferment by Prof. Tim Spector [https://amzn.to/4hU1Df5] Free resources from ZOE Eating for Better Brain Health: Your brain-gut blueprint [https://zoe.com/brainhealth?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=betterbrainhealth] How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health [https://zoe.com/2026?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=How%20to%20eat%20in%202026] Live Healthier: Top 10 Tips From ZOE Science & Nutrition [https://zoe.com/freeguide?utm_medium=podcast&utm_source=audio&utm_campaign=freeguide] Gut Guide - For a Healthier Microbiome in Weeks [https://zoe.com/gutguide?utm_medium=podcast&utm_source=audio&utm_campaign=gutguide] Better Breakfast Guide [https://zoe.com/breakfastguide?utm_medium=podcast&utm_source=audiot&utm_campaign=breakfastguide]
3 intermittent fasting mistakes that cancel fat loss and stop you seeing the benefits | Prof James Betts
Intermittent fasting may help with blood sugar, appetite, fat loss, and energy. But many people do it wrong. In this episode, Professor James Betts, one of the world’s leading experts on meal timing and its metabolic effects, explains what fasting actually is, how long you need to fast to see changes, and the key mistakes that can stop the benefits. Today, we break down what happens in your body when you stop eating and explain why it may support weight loss and blood sugar control, but also why fasting doesn’t work for everyone. You will learn why breakfast may not matter, why the 5:2 diet often fails, and why eating even small amounts can stop a true fast. By the end of this episode, you will understand what counts as a real fast, how long your eating window may need to be, why longer is not always better if you cannot stick to it, and why planning your first meal matters, because hunger can drive poor choices. If fasting can work, but is not magic, what actually makes the difference: the timing, the consistency, or simply eating less? 🌱 Try our science-backed and tasty wholefood supplement Daily 30 [https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=d30] Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE [https://zoe.com/buymembership?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=BAU] Follow ZOE on Instagram [https://www.instagram.com/zoe/]. Timecodes 00:00 Intro 02:30 The answers that completely contradict fasting advice 09:10 What fasting really means (it’s not what you think) 12:10 Why most people never actually fast 14:25 Why “eat to fuel your day” may be wrong 16:00 The 3 types of fasting people confuse 17:30 Why 5:2 might not work the way you think 18:15 The tiny mistake that ruins a fast 19:45 Why stricter fasting can feel easier 20:20 Why hunger disappears after a few days 21:20 What happened when he fasted for 5 days 22:35 What you can actually have during a fast 24:25 Do coffee and tea break your fast? 26:20 The truth about breakfast (finally tested) 28:15 The breakfast result no one expected 29:15 The hidden downside of fasting 32:20 What your body switches to when you stop eating 34:25 What really happens on day two of fasting 35:30 Why fasting might improve your health 37:05 Does fasting reduce inflammation? 38:25 What fasting actually helps with 39:20 How much weight people really lose 40:00 The most effective way to fast 41:00 The minimum fasting window that works 42:30 Who benefits most from fasting 44:30 Should you exercise before eating? 47:20 Do your eating times need to be consistent? 50:25 Does olive oil secretly break a fast? 51:45 The one rule for breaking a fast 53:40 The biggest takeaway about fasting 58:15 Should you actually try fasting? 📚Books by our ZOE Scientists The Food For Life Cookbook [https://amzn.to/4amfIMX] Every Body Should Know This by Dr Federica Amati [https://amzn.to/4blJsLg] Food For Life by Prof. Tim Spector [https://amzn.to/4amZinu] Ferment by Prof. Tim Spector [https://amzn.to/4hU1Df5] Good Mood Food (preorder) by Prof. Tim Spector [https://amzn.to/4l9oXat] Free resources from ZOE The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra [http://zoe.com/hertility?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=hertility] Eating for Better Brain Health: Your brain-gut blueprint [https://zoe.com/brainhealth?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=betterbrainhealth] How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health [https://zoe.com/2026?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=How%20to%20eat%20in%202026] Live Healthier: Top 10 Tips From ZOE Science & Nutrition [https://zoe.com/freeguide?utm_medium=podcast&utm_source=audio&utm_campaign=freeguide] Gut Guide - For a Healthier Microbiome in Weeks [https://zoe.com/gutguide?utm_medium=podcast&utm_source=audio&utm_campaign=gutguide] Better Breakfast Guide [https://zoe.com/breakfastguide?utm_medium=podcast&utm_source=audiot&utm_campaign=breakfastguide] Mentioned in today's episode Effect of the 5:2 Diet on Weight Loss and Cardiovascular Disease Risk [https://pmc.ncbi.nlm.nih.gov/articles/PMC11876533/], The International Journal of Endocrinology (2025) Intermittent fasting ‘no magic bullet for weight loss’ [https://www.science.org/doi/10.1126/scitranslmed.abd8034], Science Translational Medicine (2021) Bath Breakfast Project [https://link.springer.com/article/10.1186/1745-6215-12-172], Springer (2011) The role of intermittent fasting and meal timing in weight management and metabolic health [https://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/role-of-intermittent-fasting-and-meal-timing-in-weight-management-and-metabolic-health/D1317A634DBD94CC4019E26E435032F5]. Proceedings of the Nutrition Society, (2020) The causal role of breakfast in energy balance and health: a randomized controlled trial in lean adults [https://pmc.ncbi.nlm.nih.gov/articles/PMC4095658/]. American Journal of Clinical Nutrition, (2014) Nutrient timing and metabolic regulation [https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP280756]. The Journal of Physiology, (2022) Calorie counting vs. minute counting; does nutrient timing matter for weight-loss? [https://journals.lww.com/co-clinicalnutrition/abstract/2025/07000/calorie_counting_vs__minute_counting__does.8.aspx?context=latestarticles] Current Opinion on Clinical Nutrition and Metabolic Care, (2025) Have feedback or a topic you'd like us to cover? Let us know here [https://gf6hx47iu5g.typeform.com/topicsuggestion]. Episode transcripts are available here [https://zoe.com/learn/category/podcasts].
Most replayed moment: Keeping mobility as you age | Gabby Reece & Federica Amati
Today we’re talking about mobility well as you age. As we get older, staying mobile becomes even more important. But often, it also becomes more difficult too. So today, we’re going to break down some barriers, take the slog out of staying active, and make movement fun. I’m joined by Gabby Reece and Dr Federica Amati to explore simple ways to stay agile as we age. From the surprising benefits of walking backwards, jumping in a swimming pool, and not wearing shoes. 📚Books by our ZOE Scientists The Food For Life Cookbook [https://amzn.to/4amfIMX] Every Body Should Know This by Dr Federica Amati [https://amzn.to/4blJsLg] Food For Life by Prof. Tim Spector [https://amzn.to/4amZinu] Ferment by Prof. Tim Spector [https://amzn.to/4hU1Df5] Free resources from ZOE How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health [https://zoe.com/2026?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=How%20to%20eat%20in%202026] Live Healthier: Top 10 Tips From ZOE Science & Nutrition [https://zoe.com/freeguide?utm_medium=podcast&utm_source=audio&utm_campaign=freeguide] Gut Guide - For a Healthier Microbiome in Weeks [https://zoe.com/gutguide?utm_medium=podcast&utm_source=audio&utm_campaign=gutguide] Better Breakfast Guide [https://zoe.com/breakfastguide?utm_medium=podcast&utm_source=audiot&utm_campaign=breakfastguide] Have feedback or a topic you'd like us to cover? Let us know here [https://gf6hx47iu5g.typeform.com/topicsuggestion]Listen to the full episode https://podcasts.apple.com/gb/podcast/zoe-science-nutrition/id1611216298?i=1000621753479here [https://podcasts.apple.com/gb/podcast/zoe-science-nutrition/id1611216298?i=1000699020865]
How to tell if your poo is normal and the 5 warning signs you shouldn't ignore | Dr Trisha Pasricha
Most people think you need to poo every day to be healthy. You don’t. In this episode, we explain how to tell if your poo is normal, the warning signs you shouldn’t ignore, and the gut mistake you may be making on the toilet every day. Dr Trisha Pasricha, a leading Harvard gastroenterologist, a columnist for the Washington Post and author of the book You’ve Been Pooping All Wrong [https://amzn.to/4uyVRFT], explains how your poo, gut health, and disease risk are linked, and when you should see a doctor. Dr Pasricha guides us through why frequency, colour, and consistency all matter, and why there is no single “normal.” You’ll learn how to spot changes that could signal disease, including early warning signs linked to cancer and long-term brain health. You’ll hear simple advice you can use straight away. This includes how to recognise your normal pattern, what changes to look out for, and how to avoid the common toilet habit that may affect your gut. Are you looking at your poo every day? And, if not, what might you notice if you did? 🌱 Try our science-backed and tasty wholefood supplement Daily 30 [https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=d30] Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE [https://zoe.com/buymembership?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=BAU] Follow ZOE on Instagram [https://www.instagram.com/zoe/]. Timecodes 00:00 Intro 03:11 Your phone on the toilet: hidden risk? 07:26 Your colon runs on a clock 10:40 The illness that changed his gut for years 13:05 Why you should look before you flush 15:25 The poo colours you should never ignore 16:25 Why this sign is rising in younger adults 18:15 The stool colour doctors treat as urgent 19:27 What “perfect” poo actually looks like 21:05 What holding it in really does 23:05 The 3 things that control your bowel movements 25:35 Why gut problems are getting worse 26:43 The posture fix most people miss 27:35 The phone habit linked to 46% higher risk 29:47 Why your phone keeps you stuck there 32:35 The hidden gut–brain connection 34:50 What stress really does to your gut 36:50 Your gut may be controlling more than you think 38:50 Is IBS really misunderstood? 41:05 The theory that changes how we see Parkinson’s 44:15 The gut damage linked to future brain disease 47:45 The simple rule for better bowel movements 49:00 The foods that changed gut health in weeks 50:22 The surprising fix for constipation 52:05 The 2 habits most people ignore 54:31 A 60-second trick to calm your gut 55:30 If you change one thing, make it this 56:10 What matters most 📚Books by our ZOE Scientists The Food For Life Cookbook [https://amzn.to/4amfIMX] Every Body Should Know This by Dr Federica Amati [https://amzn.to/4blJsLg] Food For Life by Prof. Tim Spector [https://amzn.to/4amZinu] Ferment by Prof. Tim Spector [https://amzn.to/4hU1Df5] Good Mood Food (preorder) by Prof. Tim Spector [https://amzn.to/4l9oXat] Free resources from ZOE Eating for Better Brain Health: Your brain-gut blueprint [https://zoe.com/brainhealth?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=betterbrainhealth] Gut Guide - For a Healthier Microbiome in Weeks [https://zoe.com/gutguide?utm_medium=podcast&utm_source=audio&utm_campaign=gutguide] Better Breakfast Guide [https://zoe.com/breakfastguide?utm_medium=podcast&utm_source=audiot&utm_campaign=breakfastguide] Mentioned in today's episode You’ve Been Pooping All Wrong by Dr Trisha Pasricha [https://amzn.to/4uyVRFT] Gastrointestinal Symptoms in the United States [https://pmc.ncbi.nlm.nih.gov/articles/PMC6453579/#:~:text=RESULTS:,05).], The American Journal of Gastroenterology (2018) Smartphone use on the toilet and the risk of hemorrhoids [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0329983], PLOS One (2025) Impacts of Gut Bacteria on Human Health and Diseases [https://pmc.ncbi.nlm.nih.gov/articles/PMC4425030/], International Journal of Molecular Sciences (2015) Association between Early Adverse Life Events and Irritable Bowel Syndrome [https://pmc.ncbi.nlm.nih.gov/articles/PMC3311761/], CGH (2011) Management of Gastrointestinal Symptoms in Parkinson's Disease: A Comprehensive [https://pubmed.ncbi.nlm.nih.gov/38260966/], National Library of Medicine (2024) Constipation and risk of dementia in adults [https://pmc.ncbi.nlm.nih.gov/articles/PMC12173855/], Frontiers (2025) Gastrointestinal issues and Autism Spectrum Disorder [https://pmc.ncbi.nlm.nih.gov/articles/PMC8608248/], Child and Adolescent Psychiatric Clinics of North America (2020) Stanford fermented foods study [https://med.stanford.edu/news/all-news/2021/07/fermented-food-diet-increases-microbiome-diversity-lowers-inflammation.html] Ultra-Processed Food Consumption and Irritable Bowel Syndrome [https://pmc.ncbi.nlm.nih.gov/articles/PMC12655096/], Nutrients (2025) Have feedback or a topic you'd like us to cover? Let us know here [https://gf6hx47iu5g.typeform.com/topicsuggestion]. Episode transcripts are available here [https://zoe.com/learn/category/podcasts].
Most replayed moment: Lessons from a 5000-year-old diet | Frank Maixner & Tim Spector
Today we’re going prehistoric. We have to stay sharp at ZOE. Nutritional science moves fast, so it’s important for us to stay up to date with new discoveries and the latest advice. However, every now and then, it helps to look back - way back. In this recap, we’re turning to a rather unusual teacher: a 5,000-year-old Iceman, preserved in ice and carrying clues about the diet of our ancient ancestors. I’m joined by Frank Maixner and Professor Tim Spector to uncover what this prehistoric man ate and what those findings can teach us about our diet today. 🌱 Try our new plant based wholefood supplement - Daily30+ [https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30] *Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system 📚Books by our ZOE Scientists The Food For Life Cookbook [https://amzn.to/4amfIMX] Every Body Should Know This by Dr Federica Amati [https://amzn.to/4blJsLg] Food For Life by Prof. Tim Spector [https://amzn.to/4amZinu] Ferment by Prof. Tim Spector [https://amzn.to/4hU1Df5] Free resources from ZOE How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health [https://zoe.com/2026?utm_medium=zoe_podcast&utm_source=audio&utm_campaign=How%20to%20eat%20in%202026] Live Healthier: Top 10 Tips From ZOE Science & Nutrition [https://zoe.com/freeguide?utm_medium=podcast&utm_source=audio&utm_campaign=freeguide] Gut Guide - For a Healthier Microbiome in Weeks [https://zoe.com/gutguide?utm_medium=podcast&utm_source=audio&utm_campaign=gutguide] Better Breakfast Guide [https://zoe.com/breakfastguide?utm_medium=podcast&utm_source=audiot&utm_campaign=breakfastguide] Have feedback or a topic you'd like us to cover? Let us know here [https://gf6hx47iu5g.typeform.com/topicsuggestion] Listen to the full episode https://podcasts.apple.com/gb/podcast/zoe-science-nutrition/id1611216298?i=1000621753479here [https://podcasts.apple.com/gb/podcast/zoe-science-nutrition/id1611216298?i=1000567485669]
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