Good Medicine Podcast

Why Sleep Impacts Nearly Everything | Dr. David & Jeremiah Bearss

Sleep impacts nearly every aspect of human health. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss why sleep may be one of the most important and overlooked pillars of long-term health. They explore how poor sleep affects mood, metabolism, cardiovascular risk, obesity, and overall lifespan, as well as the biological consequences of even a single night of sleep deprivation. The conversation also highlights the importance of taking ownership of personal health through consistent habits like sleep, exercise, and nutrition. Topics covered include: • Why sleep impacts mood, lifespan, and metabolic health• How sleep deprivation affects insulin sensitivity• The role of sleep, diet, and exercise in long-term health 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

Why GLP-1s May Not Be the Full Answer | Dr. David & Jeremiah Bearss

GLP-1 drugs have changed the conversation around weight loss, but are they the complete solution? In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the benefits and downsides of GLP-1 medications, including how they impact exercise, muscle mass, and long-term weight management. They explore why many people feel poorly while taking these medications, why that can reduce physical activity, and why exercise remains one of the most important components of healthy weight loss. The conversation also looks at what happens after stopping GLP-1 therapy and why regaining weight may come with unintended consequences for body composition. Finally, they discuss AMPK and the idea of developing therapies that could help support the body by mimicking some of the biological signals associated with exercise. Topics covered include: • The benefits and drawbacks of GLP-1 medications• Why muscle loss matters during weight reduction• The future of exercise-signaling therapies like AMPK 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

The Problem With Mouse Models in Drug Development | Dr. David & Jeremiah Bearss

Drug development takes an average of 15 years, costs billions of dollars, and most therapies still fail before reaching patients. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss one of the biggest problems in modern drug development: animal models that may not accurately predict what happens in humans. They explore why only a small percentage of therapies that work in mice ultimately succeed in people, how that impacts timelines and costs, and why the industry may need to rethink how therapies are tested. The conversation also looks at the broader implications for pharmaceutical pricing, innovation, and the future of medicine if more predictive testing systems can be developed. Topics covered include: • Why most therapies that work in mice fail in humans• The cost and timeline challenges in drug development• The future of more predictive testing systems 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]

Why More Young People Are Getting Cancer | Dr. David & Jeremiah Bearss

Cancer is being diagnosed in younger people more than ever before. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the growing trend of cancer diagnoses in individuals under the age of 50 and why this shift is raising concern. They explore data showing increased risk in younger generations, including a significant rise in colon cancer diagnoses compared to previous decades. The conversation also looks at outcomes, which can be worse for those diagnosed at a younger age, and what this may suggest about when cancer actually begins developing. This raises an important question. What has changed in recent decades that could be contributing to increased cancer risk in younger populations? Topics covered include: • Rising cancer rates in younger generations • Trends in colon cancer diagnoses under 50 • The importance of early exposure and long-term risk 🎧 Listen on Spotify and Apple Podcasts 📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsors BioHive: https://www.biohive.com Galvan: https://galvan.sng.link/D4mh8/oe8k/litt Follow Good Medicine Podcast Insta: https://www.instagram.com/good.medicine.podcast/ X: https://x.com/GoodMedicinePod TikTok: https://www.tiktok.com/@good.medicine.podcast LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/

Is China Taking Over Drug Development? | Dr. David & Jeremiah Bearss

The global landscape of drug development is changing rapidly. In this episode of the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss discuss the rise of China as a major force in biotech and pharmaceutical innovation. Over the past several years, China has moved from a relatively small player to one of the most active regions for drug development and major deal-making. By changing how drugs are developed, including speed, cost, and efficiency, Chinese companies are increasingly competing on a global scale. They explore what this shift means for U.S. biotech companies, the challenges of competing in a faster and more cost-effective system, and how global partnerships are evolving as a result. The conversation also touches on the pressure facing large pharmaceutical companies, including upcoming patent expirations and the need to replace significant revenue, which may further accelerate global collaboration. Topics covered include: • The shift in biotech deal-making toward China• Competitive pressures facing U.S. companies• The impact of patent expirations on global strategy 🎧 Listen on Spotify and Apple Podcasts📺 Subscribe for more conversations on science, medicine, and innovation. Thank you to our sponsorsBioHive: https://www.biohive.com [https://www.biohive.com]Galvan: https://galvan.sng.link/D4mh8/oe8k/litt [https://galvan.sng.link/D4mh8/oe8k/litt] Follow Good Medicine PodcastInsta: https://www.instagram.com/good.medicine.podcast/ [https://www.instagram.com/good.medicine.podcast/]X: https://x.com/GoodMedicinePod [https://x.com/GoodMedicinePod]TikTok: https://www.tiktok.com/@good.medicine.podcast [https://www.tiktok.com/@good.medicine.podcast]LinkedIn: https://www.linkedin.com/company/goodmedicinepodcast/ [https://www.linkedin.com/company/goodmedicinepodcast/]