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Next Door Neuro

Podcast by Dr. Jamey Maniscalco

English

Technology & science

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About Next Door Neuro

Everything you care about - how you show up at work, at home, and for yourself - depends on brain health. Next Door Neuro makes brain science approachable and actionable, helping you build small, sustainable habits that fuel your brain and fuel your life.

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21 episodes

episode We've Lost Control of Our Attention - Lab Notes artwork

We've Lost Control of Our Attention - Lab Notes

Why does it feel harder than ever to focus deeply? Why do so many of us reach for our phones without consciously deciding to? And why does stillness sometimes feel strangely uncomfortable? In this episode of Next Door Neuro – Lab Notes, I explore a realization I’ve been having lately: I’m slowly losing the ability to direct my own attention. And I don’t think I’m alone... Humans evolved in environments filled with quiet. Downtime. Stillness. Boredom. Those moments created space for thinking, reflection, creativity, and deciding what actually deserved our attention. But modern life increasingly floods those same systems. Notifications. Email. Social media. News. None of these things are inherently bad. But increasingly, I wonder: Are we choosing what we pay attention to? Or is our attention increasingly being chosen for us? Importantly, this isn’t about eliminating technology. It’s about learning to notice the pull. Because attention is trainable. The brain adapts. And reclaiming our ability to intentionally direct attention may be one of the most important skills we develop in modern life. — Timestamps: 00:55 – Humans evolved with quiet 01:56 – Our brains seek novelty 02:48 – We now live in abundance 04:43 – Attention shapes our experience 05:40 – Notice the pull 05:55 – Choose what deserves your attention

Yesterday - 6 min
episode Productivity Is Broken | Emily Guerra artwork

Productivity Is Broken | Emily Guerra

What if the problem isn’t that we’re lazy, distracted, or undisciplined… …but that many of the ways we’ve been taught to work are fundamentally misaligned with how the brain actually functions? For a long time, productivity has meant: - Doing more. - Working longer. - Checking more boxes. - Pushing harder. And honestly, for much of college and graduate school, I wore overworking like a badge of honor. Minimal sleep. 16-hour days. Constant stimulation. Always feeling like I should be doing more. But looking back at that time, I wasn't truly thriving. I struggled to rest. To think deeply. To feel present. To integrate what I was learning. And eventually, I realized that productivity and fulfillment are not the same thing. In this conversation, I sit down with productivity coach and founder of The Productivity Flow, Emily Guerra. And what I appreciate about Emily’s approach is that she doesn’t just talk about getting more done, she talks about redefining productivity entirely. We explore: • Why modern productivity culture increasingly treats humans like machines • How hustle culture has shaped our relationship with work • Why rest, stillness, movement, and recovery are essential for focus and creativity • How smartphones and constant stimulation impact dopamine, motivation, and attention • Why many of us increasingly outsource emotional regulation to technology • How small environmental changes can dramatically shift behavior • And how to build a more intentional and sustainable relationship with work, technology, and ourselves This conversation isn’t just about productivity. It’s about attention, energy, presence, meaning, and how we live well inside environments that constantly pull at our brains. ------------ About Emily Emily Guerra is a Productivity Life Coach, mindful productivity speaker, and founder of The Productivity Flow. Through coaching, workshops, and speaking, Emily helps people build more sustainable and intentional relationships with work, productivity, focus, and burnout prevention. Her work blends productivity, neuroscience, mindset, and emotional wellbeing - helping individuals move away from constant overwhelm and toward a more balanced, fulfilling, and effective way of living and working. Learn more: https://theproductivityflow.com/ [https://theproductivityflow.com/] Instagram: @theproductivityflow  [https://www.instagram.com/theproductivityflow/] LinkedIn: Emily Guerra [https://www.linkedin.com/in/emily-guerra-the-productivity-flow/]

19 May 2026 - 1 h 15 min
episode Why the Brain Pushes Back | Lab Notes artwork

Why the Brain Pushes Back | Lab Notes

Why do the things we use to reduce stress, boredom, discomfort, or exhaustion so often end up creating more of those exact feelings over time? In this episode of Next Door Neuro - Lab Notes, I explore one of the most important principles in neuroscience and addiction: The brain creates the opposite of what you repeatedly use to change your emotional or physiological state. Using caffeine as a personal example, I unpack why the brain “pushes back,” how repeated relief and stimulation can slowly shift our baseline, and why this idea may help explain everything from addiction… to compulsive phone checking… to why boredom suddenly feels so uncomfortable. But importantly, this episode isn’t about fear or eliminating pleasure. It’s about understanding how the brain adapts, and using that knowledge to work with your brain rather than constantly fighting against it. In this episode, I explore: * why the brain adapts and pushes back * how repeated behaviors slowly shape what feels normal * why modern environments make emotional regulation harder * practical tools for interrupting automatic patterns * rebuilding earned reward * training stillness again * and how small repeated actions can create meaningful change over time If your brain fuels your life… what fuels your brain? ⸻ Timestamps:  00:00 – The caffeine realization  03:09 – The brain pushes back  03:58 – The brain learns from repetition  04:37 – We’re outsourcing emotional regulation  06:40 – Create moments of interruption  07:34 – Rebuild earned reward  08:58 – Train stillness again  09:46 – Small repeated changes matter

14 May 2026 - 10 min
episode Modern Life Is Becoming More Addictive | Lab Notes artwork

Modern Life Is Becoming More Addictive | Lab Notes

Why does addiction still feel like it’s getting worse… despite decades of neuroscience research, treatment programs, and greater awareness than ever before? In this episode of Next Door Neuro – Lab Notes, I explore one of the most important ideas from my recent conversation with neuroscientist and bestselling author Judy Grisel: Addiction isn’t getting worse because humans suddenly became weak. It's likely getting worse because the environment changed dramatically… while the brain stayed largely the same. And importantly, this conversation isn’t just about drugs anymore. It’s about modern life more broadly: * Smartphones * Social media * Ultra-processed food * Gambling * Pornography * Endless stimulation * And constant access to quick relief, reward, and distraction. In this episode, I explore: * Why modern life may be becoming increasingly addictive * “Supernormal stimuli” and evolutionary mismatch * Why constant access changes behavior * Why boredom feels increasingly uncomfortable * Earlier exposure and adolescent brain development * And the rise of behavioral addictions. If your brain fuels your life… what fuels your brain? ⸻ Timestamps: 00:00 – Why addiction still seems to be getting worse  02:10 – Modern life is becoming increasingly addictive  03:36 – How the brain learns from repetition  04:18 – The environment changed. The brain didn’t.  04:43 – Higher potency and hyper-stimulation  06:04 – Constant access and endless stimulation  07:53 – Earlier exposure and adolescent brains  09:10 – Addiction without substances

12 May 2026 - 12 min
episode There's No Free Lunch for Your Brain | Lab Notes artwork

There's No Free Lunch for Your Brain | Lab Notes

Why do the things we use to feel better so often end up making us feel worse over time? In this episode of Next Door Neuro – Lab Notes, I unpack one of the most powerful ideas from my recent conversation with neuroscientist and bestselling author Judy Grisel: The most important thing we can teach our kids about drugs may not actually be about drugs at all. It’s about understanding how the brain responds to fast-acting, artificial relief. Because increasingly, our modern world is built around instantly changing how we feel: - social media - pornography - gambling - ultra-processed food - endless stimulation - and increasingly potent substances And while legislation and parental oversight matter, I believe we may be underestimating the power of education - especially helping people understand how the brain adapts to repeated artificial relief over time. In this Lab Notes episode, I explore a framework I’ve found personally helpful: “There’s no free lunch for your brain.” The brain isn’t trying to make us happy all the time. It’s trying to keep us balanced. And because of that, the brain adapts to repeated highs, relief, stimulation, and escape - often creating more of the very state we were trying to avoid. If your brain fuels your life… what fuels your brain? Related conversation: Why Addiction Is Getting Worse | Judy Grisel Judy Grisel is a neuroscientist, professor, bestselling author of Never Enough, and a former addict who now studies addiction and the brain. In our full conversation, we explore addiction, dopamine, modern life, and why the brain adapts the way it does.

7 May 2026 - 9 min
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