Simini Surgery Review: Equine Edition
In this episode of the Simini Equine Surgery Podcast, we explore the orthopedic research from the October 2025 issue (Issue 7) of Veterinary Surgery, where two complementary studies examine the future of equine cervical vertebral fusion. Together, they answer two fundamental questions: Which implant performs best mechanically? And how do horses actually perform after surgery? This episode follows the evolution of cervical fusion—from decades of clinical experience using the kerf cut cylinder (KCC) to emerging 3D-printed titanium plate-and-spacer technology designed to improve construct stability and long-term outcomes. In this episode: ✅ Cormier et al. — Evaluated intra-articular injection of decellularized porcine amnion/chorion suspension in horses. Both low- and high-dose groups developed inflammatory responses, but the high-dose group had more clinically evident inflammation, including increased lameness, elevated synovial and systemic SAA, and persistent signs requiring lavage and flunixin in some horses. The study concluded that dPACLS at the tested doses is not recommended for intra-articular injection because of the inflammatory response. ✅ Janicek et al. present the largest multicenter evaluation of C7–T1 ventral interbody fusion using the kerf cut cylinder implant. Reviewing 38 horses treated over a 20-year period, the authors reported an 89% hospital discharge rate, with 79% achieving successful long-term outcomes. Half of the horses returned to athletic work—including dressage, show jumping, barrel racing, hunters, and western pleasure—while many others regained comfortable pasture soundness. The study also provides valuable surgical pearls for one of the most anatomically challenging regions of the equine cervical spine and highlights laryngeal spasm as the most significant perioperative complication requiring careful airway management. ✅ Zedler et al. evaluated a 3D-printed titanium plate and spacer construct against the traditional 4.5-mm locking compression plate (LCP) in an ex vivo biomechanical model of C4–C5 fusion. Although both constructs demonstrated similar stiffness and failure loads, the 3D implant was significantly less likely to fail through displaced vertebral fracture or screw pullout during extension loading. The findings suggest that modern patient-specific implant design may improve mechanical reliability while providing a scaffold for future osseous integration. Together, these studies illustrate how clinical experience and engineering innovation are converging to improve treatment options for horses with cervical vertebral stenotic myelopathy (CVSM). Long-term outcomes demonstrate that cervical fusion is no longer simply a salvage procedure—it is increasingly becoming a realistic path back to athletic performance for appropriately selected horses. 🎓 Journal Articles Discussed * Cormier et al. — Inflammatory Response Following Intra-Articular Injection of Decellularized Porcine Amnion/Chorion in Horses Janicek et al. — Multicenter Results for C7–T1 Ventral Interbody Fusion in Horses Using the Kerf Cut Cylinder Zedler et al. — Ex Vivo Biomechanical Testing of a Three-Dimensional Printed Titanium Plate and Spacer Construct and 4.5 mm Locking Compression Plate for Ventral Cervical Fusion of C4–C5 in the Horse 📚 From the October 2025 Issue (Issue 7) of Veterinary Surgery 🎁 Want to learn more about Simini Protect Lavage or request a sample? Learn More: www.simini.com [http://www.simini.com] Request a Sample: https://www.simini.com/evaluation-kit [https://www.simini.com/evaluation-kit]
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