Anesthesiology Journal's podcast

Moderator: James P. Rathmell, M.D. Participants: Carmen Bozic, M.D. Articles Discussed: Suzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials [https://journals.lww.com/anesthesiology/fulltext/2025/06000/suzetrigine,_a_nonopioid_nav1_8_inhibitor_for.24.aspx] Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain [https://journals.lww.com/anesthesiology/fulltext/2025/06000/suzetrigine__first_in_a_new_class_of_nonopioid.11.aspx]

Moderator: James P. Rathmell, M.D. Participants: Rebecca L. Wu, M.D. and Max B. Kelz, M.D., Ph.D. Articles Discussed: TAK-925 (danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-Induced Respiratory Depression and Sedation Without Affecting Analgesia in Healthy Adult Males [https://journals.lww.com/anesthesiology/fulltext/2025/04000/tak_925__danavorexton_,_an_orexin_receptor_2.12.aspx] Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape [https://journals.lww.com/anesthesiology/fulltext/2025/04000/alluring_potential_to_accelerate_emergence_and.7.aspx] Transcript [%E2%80%9Dhttps:/dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/anesthesiology/Danavorexton_Promotes_Respiration_and_Wakefulness.pdf%E2%80%9D]

Moderator: BobbieJean, M.D. Participants: Douglas Colquhoun, M.B., M.Sc., M.P.H. and Stephan R. Thilen Articles Discussed: Neuromuscular Blockade and Antagonism in Patients with Renal Impairment: A Multicenter Retrospective Cross Sectional Study [https://journals.lww.com/anesthesiology/abstract/9900/neuromuscular_blockade_and_antagonism_in_patients.646.aspx] On and Off Label Use of Sugammadex in Patients with Renal Impairment in the 6 ½ Years Following FDA Approval [https://journals.lww.com/anesthesiology/fulltext/2025/06000/sugammadex_in_chronic_kidney_disease_.7.aspx] Transcript [%E2%80%9Dhttps:/dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/anesthesiology/Sugammadex_Use_in_Renal_Impairment.pdf%E2%80%9D]

Creator: James P. Rathmell, M.D., M.B.A. June 2025, Volume 142, Issue 6 [https://pubs.asahq.org/anesthesiology/issue/142/6] Overview of June issue original studies. Transcript [https://dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/anesthesiology/June_2025_EIC_Podcast.pdf]

Moderator: BobbieJean Sweitzer, M.D. Participants: Daqing Ma, Ph.D. and Kate Leslie, M.B.B.S., M.D. Articles Discussed: Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial [https://journals.lww.com/anesthesiology/fulltext/2025/04000/pyridoxine_prevents_postoperative_nausea_and.14.aspx] B6 or Be Sick? Pyridoxine to Prevent Postoperative Nausea and Vomiting [https://journals.lww.com/anesthesiology/fulltext/2025/04000/b6_or_be_sick__pyridoxine_to_prevent_postoperative.9.aspx] Transcript [%E2%80%9Dhttps:/dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/anesthesiology/Pyridoxine_for_Posoperative_Nausea_and_Vomiting.pdf%E2%80%9D]