Bioprocessing Unfiltered

Episode: 9 - Jack Scarcelli on Moving Beyond One Host, One Vector, One Process for Today’s Cell Line Development

In this episode of Bioprocessing Unfiltered, Jack Scarcelli, senior director and head of cell line development at Sanofi, speaks with host Hussain Dahodwala, professor of upstream process development at University of Maryland’s Institute of Bioscience and Biotechnology Research, to discuss technical and strategic challenges in the next gen cell line development in the biopharmaceutical industry. Scarcelli traces his career journey, shares lessons learned over a successful career, and offers thoughtful advice for early career scientists. Plus, some highlights from the upcoming Bioprocessing Summit in Boston in August and hope for collaboration to shape the future.   Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/] Sanofi [https://www.sanofi.com/en]    Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

Episode: 8 - Jack Prior of Sanofi on AI Readiness in Biomanufacturing

In this episode of Bioprocessing Unfiltered, Jack Prior, head of process monitoring and data science and AI strategy at Sanofi, explores how AI has evolved from early expert systems to machine learning, generative AI, and agentic AI, and what that means for biomanufacturing today. He explains why digital transformation has not automatically created usable data, and why the real challenge is turning fragmented information from manufacturing systems into accessible, authentic, and analysis-ready data. Jack shares a practical framework for assessing data maturity and argues that the biggest near-term opportunity for AI is reducing friction in data engineering, troubleshooting, tech transfer, and decision support across bioprocessing organizations.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]  Sanofi [https://www.sanofi.com/en]      Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

Episode: 7 - Anurag Rathore on Platform Processes, Chromatography, and Expanding Education

Anurag Rathore, professor of chemical engineering at the Indian Institute of Technology Delhi, joins Bioprocessing Unfiltered with host Alois Jungbauer to discuss his long career in advancing bioprocessing engineering. Rathore shares his thoughts on chromatography, using platform processes to accelerate process development, how infinity capture can be a way to arrive at platform processes, and if there is a need for alternative methods. He also explores updates needed to the traditional curriculum of biochemical engineering—and if the next generation should know how to use AI and ML—and his view on bioprocess and development.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]  Indian Institute of Technology Delhi [https://home.iitd.ac.in/]  Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

Episode: 6 - Fireside Chat: Innovation and Investment in Biomanufacturing of Future Medicine

At the most recent Bioprocessing Summit, David Y. H. Chang, CEO of Taiwan Bio-Manufacturing Company; Bo Wiinberg, Chief Business Development Officer of Novo Nordisk Foundation Cellerator; and Paul Lewus, Vice President of Site Operations at Amgen gathered for a fireside chat moderated by Ran Zheng, former CEO of Landmark Bio, to discuss the technologies and innovations shaping the future of biomanufacturing. The conversation explored upcoming trends, investment opportunities, and modalities into the next decade, as well as the question: how should the industry best prepare for all of it?  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/] Landmark Bio [https://landmarkbio.com/] Novo Nordisk Foundation Cellerator [https://novonordiskfonden.dk/en/projects/novo-nordisk-foundation-cellerator/] Taiwan Bio-Manufacturing Company (TBMC) [https://tbmcbio.com/] Amgen [https://www.amgen.com/]    Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.

Episode: 5 - Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations, Part 2

Picking up from their previous conversation on Bioprocessing Unfiltered, Andrew Sinclair, president and founder of BioPharm Services Ltd., and host William Whitford, founder of Oamaru BioSystems, discuss improving manufacturing efficiency, including process mass intensity and setting up parameters, and more on Sinclair’s long career and valuable experiences in the industry. Sinclair also shares advice on helping someone who cannot meet parameters, how to navigate new profusions, and default values that can help others with their processes.  Links from this episode:   Bioprocessing Summit [https://www.bioprocessingsummit.com/]   Biopharm Services [https://biopharmservices.com/]    Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.