Health Disaster or Miracle Cure? A Doctor's Honest Answer | ft. Dr. Sam Zand

Health Disaster or Miracle Cure? A Doctor's Honest Answer | ft. Dr. Sam Zand

Are GLP-1 medications like Ozempic, Mounjaro, Wegovy, and Retatrutide a genuine breakthrough — or are we sleepwalking into a health crisis? In this episode, we sit down with Dr. Sam Zand, a double board-certified physician and certified Obesity Medicine specialist, to get an honest, science-backed answer. Dr. Zand is the Medical Director of Evolve Longevity Clinic in Miami, where he works with high performers to optimise body composition, metabolic health, energy, and longevity. He's seen firsthand what these medications do — and don't do — and he's not here to sell you either direction. In this episode we cover: → What GLP-1 medications are, how they work, and who they're actually for → The real side effects of Ozempic, Mounjaro and Wegovy — including muscle loss, Ozempic face, and becoming skinny-fat → Why GLPs don't work for everyone — and whether you can out-eat them → How to protect your muscle mass and body composition while on GLP medications → The effect of GLP-1s on the brain — and their emerging role in treating addiction → GLP microdosing: what it is and why some patients are doing it → Long-term use: how long do you actually need to be on these medications? → Whether decline is an inevitable part of ageing — and what the science actually says This episode is for you if: → You're curious about GLP-1 weight-loss medications but don't know where to start → You're already on Ozempic, Wegovy, or Mounjaro and want to understand the full picture → You're concerned about muscle loss, body composition, or long-term health impacts → You work in health, fitness, or longevity medicine and want a clinician's perspective Guest Links: → Dr. Sam Zand on Instagram: instagram.com/doctor.zand → Evolve Longevity Clinic on Instagram: instagram.com/evolve.longevity → Evolve Longevity Clinic website: evolvelongevity.co

Jorge Perez | "The Shut The F*ck Up Method"

Jorge Perez has been a talent agent, coach and broker for celebrities in Hollywood for the last 20 years. He has brokered deals for Lady Gaga, Lindsay Lohan, Naomi Campbell and Jennifer Lopez. His passion for personal development led him to write his book, “The Shut the F*ck Up Method,” in which he shares the tools that helped him win his way to the top in Hollywood. His book is currently being used by Dr Joe Dispenza’s corporate team for interpersonal training. Most recently, he translated the book into Spanish, where Alicia Machado and Alejandro Chaban raved about how easy and powerful this method is for people. Jorge is currently taking on clients who want to take their lives to the next level, both personally and financially.   * The 'behind the scenes' of Dr Joe Dispenza retreats * How our thoughts create our reality and even change the expression of our genes! * The Shut the F*ck Up method and the 10 commandments for living a better life in detail * Lots of life stories and lessons   This episode is a little bit different. Rather than discussing scientific facts in depth, we had a light-hearted conversation about Jorge's "Shut The F*ck Up" method for living a better, happier life. We cover: Whether you are stuck in a vicious cycle of negative thinking, catch yourself often gossiping too much and falling into people's life dramas, or if you need a refresher on positive thinking and the power of thoughts, this episode will fill your cup and provide lots of practical advice and entertainment. Links: Instagram https://www.instagram.com/jorgeperezjr/ [https://www.instagram.com/jorgeperezjr/] STFU Method website: https://www.stfumethod.com/ [https://www.stfumethod.com/]

What if the secret to a longer, healthier life came down to a single protein?

In this episode, we're joined by Dr Uberto Mondolfi — CEO of Healthy Longevity Clinic and an expert in integrative wellness — to explore the cutting edge of anti-ageing science, including Klotho, the protein that researchers believe could fundamentally change how we age.We cover:• The difference between longevity and health span — and why it matters• Klotho: what it is, what it does, and why scientists are so excited• Key biomarkers of ageing, including telomere length and mitochondrial function• Innovative procedures like therapeutic plasma exchange and hyper-concentrated PRP• Practical, free lifestyle and nutrition habits that can genuinely extend your health spanWhether you're interested in the science of longevity or simply want to feel better for longer, this conversation is packed with insight and actionable takeaways.🔗 Learn more about Dr Mondolfi's work: https://www.healthylongevity.clinic/ 📸 Instagram: @healthylongevityclinic | @longevitylounge.hlc

Why marathons can damage your gut with the leading expert in sports dietetics, Dr Ricardo Da Costa

Professor Ricardo Da Costa is a globally recognised leader in Sports Dietetics and Extremes Physiology at Monash University. He currently serves as Director of Research, Deputy Coordinator of the PhD Program, and Chair of the Industry Engagement Group within the Department of Nutrition, Dietetics & Food at Monash University. He leads a world-class hub for research, education, and consultancy, and directs the Monash University BASE Facility Nutrition & Exercise Clinic, which delivers cutting-edge testing and advisory services to athletes and athlete support practitioners, ranging from recreational amateurs to elite Olympic athletes. Dr Da Costa is internationally recognised as a leading expert on the impact of exercise on gut health, which is why we chat about Exercise-Induced Gastrointestinal Syndrome in Athletes. What we love about Dr Da Costa is that he is not 'just' a scientist and expert in the field; he is also an ex-elite endurance athlete. In this episode, Dr Da Costa presents the latest research and practical advice on managing gut issues in endurance and ultra-endurance events. We cover: * What is the exercise-induced gastrointestinal syndrome * Factors, symptoms and long-term consequences of exercise-induced gut damage * Dietary strategies to protect the gut and practical recommendations for athletes * Post-race recovery and gut repair Keep in mind that our discussion is around elite athletes and those who are pushing their bodies to extremes, not for someone participating in running and other endurance events for fun. Links: Profile: https://www.monash.edu/medicine/scs/researchers/ricardo-da-costa Studies: https://link.springer.com/article/10.1007/s40279-025-02186-6 https://journals.humankinetics.com/view/journals/ijsnem/33/6/article-p305.xml

Fat Loss & Better Energy: A Beginner's Guide with Nutritionist Sally O'Neil

Sally O’Neil is a clinical nutritionist, women’s transformation strategist, and the founder of Intelligent Dose. She specialises in hormonal health and body composition for women 35+, using functional testing and data-led coaching to help clients overcome fatigue, weight-loss resistance, and burnout. Through her signature method, Sally combines evidence-based nutrition with deep nervous system support to help women reclaim their energy, metabolism, and confidence. In this episode, we outline the basics of weight loss and healthy eating. We chat about ultra-processed foods, carbs, macronutrients and micronutrients, different types of diets, fasting, cortisol and even supplements. We cover: * All macronutrients (protein, carbs and fats) and the importance of whole foods * Synthetic vs natural supplements, including vitamin B6 toxicity * The calorie debate- quality vs quantity * Different types of diet This episode is for anyone trying to lose fat, regain their health and feel amazing without breaking the bank, or resorting to medications and biohacking. LINKS: Find out more about her coaching programs at www.status8020.com. Sally's Instagram https://www.instagram.com/sallyoneil/ Status 8020 https://www.instagram.com/status.8020/ Intelligentdose https://www.instagram.com/intelligentdose/ Tune into The Sally O’Neil Podcast for clinical insights made simple.