Episode 63: LC-MS Metabolomics and Next-Generation Ionization Technologies #chromatography #massspectrometry

Episode 66: Why Sustainable Labs Save Money: James Connelly, CEO of My Green Lab

Can sustainability actually make laboratories more efficient—and more profitable?In this episode of Concentrating on Chromatography,  @Organomation  [https://studio.youtube.com/channel/UC_VaXQ_xrx4881G8Fo4dxDg] General Manager David Oliva sits down with James Connelly, CEO of My Green Lab, to discuss how a grassroots movement founded by scientists evolved into the leading global organization for laboratory sustainability.James explains why sustainability is no longer just a "nice-to-have" initiative, how major pharmaceutical companies and funding organizations are driving change, and why laboratory suppliers and instrument manufacturers are becoming increasingly important in helping scientists achieve their environmental goals.Topics include:🔬 How My Green Lab grew from an academic movement into a global standard💰 Why sustainable laboratories often deliver significant financial ROI🏭 The changing role of laboratory equipment manufacturers and suppliers📊 What Scope 1, Scope 2, and Scope 3 emissions actually mean♻️ The ACT Eco Label and sustainable product design⚡ Renewable energy, recycled materials, and resilient supply chains🤖 AI-powered predictive maintenance and smart laboratory technologies🗑️ Emerging innovations in laboratory waste management🌎 Why sustainability is becoming a business imperative across life sciences🎓 The My Green Lab Ambassador and Accredited Professional programsWhether you're an analytical chemist, laboratory manager, instrument manufacturer, or simply interested in the future of scientific research, this episode provides practical insights into how sustainability is transforming laboratories around the world. Subscribe to  @ChromatographyTalk  [https://studio.youtube.com/channel/UCU9oYSK_peqfuCrwpnv4fqA] for more conversations with leaders in chromatography, mass spectrometry, sample preparation, and analytical science.#Sustainability #GreenLab #MyGreenLab #LaboratoryScience #Chromatography #MassSpectrometry #AnalyticalChemistry #LifeSciences #ESG #SciencePodcast

Episode 65: Why Scientists Need to Tell Their Story | Funding, Visibility & Industry Impact

Why should analytical chemists, chromatographers, and researchers care about science communication? Is publishing papers enough? How can scientists increase their visibility without spending hours on social media?In this episode of  @ChromatographyTalk  [https://studio.youtube.com/channel/UCU9oYSK_peqfuCrwpnv4fqA] , David is joined by Lisa Jones and Johnnie Aycock, co-hosts of  @TheNoonShow100.1  [https://studio.youtube.com/channel/UC0Eem9w82ZhQowMauATSakg] and creators of the upcoming BrightPath program on Alabama Public Radio. Together, they explore why communicating science matters—not just for public understanding, but for research funding, industry partnerships, talent development, and the future of innovation itself.From translating complex ideas with simple analogies to building relationships beyond the laboratory, this conversation offers practical advice for scientists who want their work to have a greater impact.In this episode:🔬 Why scientists need to tell their story beyond journal publications🎙️ How researchers can communicate complex science to non-scientists💡 Why visibility matters for funding, collaboration, and career opportunities🏭 Bridging the gap between academia and industry🤝 The importance of partnerships and advocacy for research📢 Practical first steps for chemists who want to promote their work🧪 Why conferences alone aren't enough to reach broader audiences🎓 How science communication can inspire the next generation of scientists🌎 The role of research in economic development and global competitiveness🎧 The vision behind BrightPath and bringing science stories to the publicMemorable topics discussed:Explaining chromatography through the analogy of making coffeeWhy researchers should "lead with why it matters"Lessons learned from interviewing scientists across AlabamaThe connection between research, workforce development, and economic growthHow communication can influence public support for scienceWhy showing up and building relationships often matters more than perfectionFeatured GuestsLisa JonesFormer University of Alabama Department of Chemistry & Biochemistry staff member (27 years)Co-host of The Noon ShowScience communication advocate and STEM enthusiastJohnnie AycockFormer President & CEO of the West Alabama Chamber of CommerceEconomic development leaderCo-host of The Noon Show🎙️ Concentrating on Chromatography explores chromatography, mass spectrometry, sample preparation, and the people advancing analytical science.If you enjoy conversations about analytical chemistry, LC-MS, GC-MS, sample preparation, and scientific careers, subscribe for future episodes featuring researchers, industry leaders, and innovators from around the world.#Chromatography #AnalyticalChemistry #MassSpectrometry #ScienceCommunication #STEM #Research #LCMS #GCMS #Chemistry #SciencePodcast #Scientists #AcademicResearch #Innovation #Spectroscopy #CareersInScience #ConcentratingOnChromatography

Episode 64: The Chemistry of Human Decomposition: GC×GC, Body Farms, and Forensic Science

In this episode of  @ChromatographyTalk  [https://studio.youtube.com/channel/UCU9oYSK_peqfuCrwpnv4fqA] David sits down with Dr. Darshil Patel, Assistant Professor of Forensic Science at the University of North Dakota, to discuss his remarkable journey from dentistry in India to becoming a leading researcher in forensic chemistry across Australia, Canada, and the United States.Dr. Patel shares how his work at human taphonomic facilities—commonly known as "body farms"—has helped advance our understanding of human decomposition and the volatile compounds released during the postmortem process. Using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC×GC-TOFMS), his research aims to improve human remains detection, cadaver dog training, and the development of future electronic sensing technologies.Topics discussed include:🔬 How a dentist became a forensic scientist🌏 Working in Australia, Canada, and the United States⚰️ What human taphonomic facilities ("body farms") really do🧪 The chemistry of human decomposition📈 Why GC×GC-TOFMS excels at analyzing complex VOC mixtures🐕 How chromatography can improve cadaver dog training🤖 The future of electronic noses and human remains detection🏔️ Challenges posed by geography and environmental conditions🏫 Building a new forensic chemistry laboratory at the University of North Dakota🔍 The future of forensic chromatographyWhether you're interested in forensic science, chromatography, mass spectrometry, or the chemistry behind real-world investigations, this episode offers a fascinating look into one of the most unique applications of analytical chemistry.#ForensicScience #GCxGC #MassSpectrometry #Chromatography #Forensics #GCMS #TOFMS #AnalyticalChemistry #HumanDecomposition #VOCs #UniversityOfNorthDakota #CadaverDogs #BodyFarm #SeparationScience

Episode 63: LC-MS Metabolomics and Next-Generation Ionization Technologies #chromatography #massspectrometry

In this episode of  @ChromatographyTalk  [https://studio.youtube.com/channel/UCU9oYSK_peqfuCrwpnv4fqA], David speaks with Joseph Corstvet from the Fernandez Lab at Georgia Tech about the future of mass spectrometry, LC-MS metabolomics, and the development of low-cost ionization technologies.Joe discusses his work using LC-MS lipidomics to monitor mesenchymal stromal cell (MSC) senescence and explains how metabolomics could eventually become a real-world quality control tool for regenerative medicine and cell therapy manufacturing.The conversation also dives into triboelectric nanogenerators (TENGs) and how these low-cost, modular ionization systems could help make mass spectrometry more portable, accessible, and affordable. Joe explains how TENG-powered electrospray ionization works, why it differs from traditional ESI, and how his group is exploring applications ranging from mass spectrometry imaging to mobile MS platforms.Topics include:• LC-MS metabolomics workflows• Lipidomics and MSC senescence• Biomarker discovery in regenerative medicine• Untargeted metabolomics challenges• TENG ionization technology• Portable and lower-cost mass spectrometry• Mass spectrometry imaging• Ion mobility and future MS trends• ASMS and the future of analytical chemistryIf you enjoy conversations about chromatography, mass spectrometry, metabolomics, and analytical chemistry innovation, be sure to subscribe to Concentrating on Chromatography.#MassSpectrometry #LCMS #Metabolomics #AnalyticalChemistry #Chromatography #Lipidomics #MassSpec #Ionization #ASMS #Biotech

Episode 62: When One Atom Changes Everything | JC Poutsma on Mass Spectrometry, Proteomics & Gas-Phase Chemistry

What happens when you replace just one atom in an amino acid?In this episode of  @ChromatographyTalk  [https://studio.youtube.com/channel/UCU9oYSK_peqfuCrwpnv4fqA] David sits down with JC Poutsma, Professor of Chemistry at William & Mary, to explore the fascinating world of gas-phase ion chemistry, peptide fragmentation, and the hidden molecular behavior revealed by mass spectrometry.Professor Poutsma explains how subtle structural changes in biomolecules can dramatically alter protein folding, fragmentation pathways, and biological activity. The conversation dives into unusual amino acids like canavanine, the “proline effect” in peptide fragmentation, ion mobility spectrometry, IR spectroscopy, and why understanding the fundamentals of chemistry still matters in modern analytical science.Whether you work in LC-MS, proteomics, physical chemistry, or analytical instrumentation—or you simply enjoy learning how molecules behave at the most fundamental level—this episode offers a fascinating look at the chemistry happening behind the spectra.Topics Discussed* What is gas-phase ion chemistry?* How mass spectrometers can function as reaction vessels* Why unusual amino acids matter* The chemistry of canavanine vs arginine* How one atom substitution changes protein behavior* Peptide fragmentation mechanisms in proteomics* The “proline effect” in tandem MS* Ion mobility spectrometry explained* IR spectroscopy for structural characterization* Why understanding analytical fundamentals still matters* Teaching chemistry in the age of AI and automation About the GuestJC Poutsma is a Professor of Chemistry at William & Mary whose research focuses on gas-phase ion chemistry, biomolecular structure, peptide fragmentation, spectroscopy, and the physical chemistry underlying mass spectrometry.#MassSpectrometry #Proteomics #AnalyticalChemistry #LCMS #MassSpec #Chemistry #IonMobility #Spectroscopy #PeptideFragmentation #PhysicalChemistry #ASMS #Chromatography