Can We Slow Aging? The Real Science Behind Longevity | Matt Kaeberlein

Mayor David Holt on Why Oklahoma City Ranks So Low in Health and Why We Need to Change It

Oklahoma City consistently ranks near the bottom in national health outcomes. The question is not whether that is true. The question is why.In this candid conversation, Mayor David Holt breaks down the structural realities behind our health challenges. From being one of the largest cities in America by land mass to an over-reliance on the automobile, Oklahoma City was not built for daily movement. When you remove walking from everyday life, the consequences show up in obesity rates, heart disease, and longevity.We discuss:• How car-dependent design impacts public health• Why Oklahoma City’s 620 square miles creates infrastructure challenges• The role of sidewalks, trails, and public wellness facilities• The link between education, income, and long-term health outcomes• How Mayor Cornett’s “This City Is Going on a Diet” campaign broke through nationally• Why business leaders should care about workforce health costs• The opportunity to leverage LA 28 and the Olympic spotlight• The importance of getting health back on the front burnerThis episode is about awareness, leadership, and momentum. If we understand the structural headwinds, we can begin building structural solutions.Mayor Holt shares his support for the Oklahoma Health Summit and the broader Healthy City Initiative as a pathway to reignite this conversation across business, schools, faith communities, and civic leadership.Join us March 9th and 10th in Oklahoma City for the Oklahoma Health Summit.Register today:https://www.healthycityinitiative.com/Let’s get health back on the front burner.

Your Body Is Not Broken: Understanding Nervous System Healing | Laura Miles

What if your exhaustion, anxiety, inflammation, and burnout are not signs that you are broken, but signs that your nervous system has been protecting you? In this conversation with Laura Miles, we explore how chronic stress reshapes the body and why so many people are stuck in survival mode without realizing it. This episode unpacks what nervous system dysregulation really means, how trauma and long-term stress alter physiology, and why healing requires more than mindset shifts alone. We discuss the difference between coping and regulating, how the body stores stress, and why learning to create safety in the body is foundational for real, sustainable health. From fight, flight, and freeze responses to practical awareness tools, this episode connects the dots between emotional health and physical well-being. If you have tried to think your way into better health but still feel wired, tired, or overwhelmed, this conversation offers a different path forward. Laura Miles brings clarity, science, and compassion to a topic that affects nearly every modern adult. Understanding your nervous system may be the missing piece in your healing journey.

The Healthy City Playbook: Data, Leadership, and Community Momentum | Betsy Price

What if a city decided it was done being unhealthy? In this powerful conversation, former Fort Worth Mayor Betsy Price shares how one of the largest cities in America transformed its trajectory by focusing on movement, community, data, and gentle nudges instead of mandates. We unpack: • How Fort Worth launched a citywide healthy community initiative • Why data must drive change, and how Gallup well-being surveys shifted momentum • How businesses reduced healthcare costs and absenteeism • Why sidewalks, streetlights, trails, and playground access matter more than we think • How faith leaders, schools, and corporations became partners in prevention • The power of engaging kids to transform entire families • Why health is about adding life to your years, not just years to your life • How city leadership can inspire grassroots movement without forcing behavior This episode is a blueprint for Oklahoma City. If Fort Worth could move the needle as one of the largest cities in America, Oklahoma City can too. But it takes champions, coalition-building, business engagement, faith partnership, and a commitment to prevention. That is exactly what the Oklahoma Health Summit is about. On March 9th and 10th in Oklahoma City, we are bringing together leaders in health, policy, business, AI, longevity, and prevention to chart a healthier future for our state. If you care about workforce health, lower healthcare costs, stronger neighborhoods, and building a healthier next generation, you need to be in the room. Register today: https://www.healthycityinitiative.com/ [https://www.healthycityinitiative.com/] March 9th and 10th Oklahoma City Let’s change the trajectory of our city.

Hormones, Heart Disease, and Prevention: What Women Have Been Missing | Tara Scott

What if one of the biggest gaps in modern healthcare is how we treat women’s hormones? In this powerful and eye-opening conversation, Dr. Tara Scott shares how infertility, menopause, heart disease, metabolic dysfunction, and chronic stress are deeply connected, and why most women are not getting the evaluation or education they deserve. We unpack: • Why 80% of OBGYNs feel ill-equipped to treat menopause • The truth about the 2001 WHI study and how hormone therapy was misrepresented • The real difference between synthetic and bioidentical hormones • Why estrogen has a protective effect on heart health • The connection between inflammation, insulin resistance, and cardiovascular disease • How stress and cortisol silently damage long-term health • Why prevention must start before menopause • The importance of advanced lipid testing, insulin screening, and early cardiometabolic detection This conversation goes beyond hormones. It is about prevention. It is about empowerment. It is about helping women connect the dots between brain fog, weight gain, migraines, mood changes, sleep disruption, and long-term disease risk. Dr. Scott will be speaking at the Oklahoma Health Summit on March 9th and 10th in Oklahoma City, where we are bringing together leaders in longevity, AI, prevention, and personalized medicine to help Oklahoma shift from reactive care to proactive health. If we want Oklahoma to move from near the bottom of national health rankings to becoming a leader in prevention, this is the conversation we need. 📍 March 9th and 10th 📍 Oklahoma City 🎟️ Register today: https://www.healthycityinitiative.com/ [https://www.healthycityinitiative.com/] Prevention starts with awareness. And awareness starts here.

Can We Slow Aging? The Real Science Behind Longevity | Matt Kaeberlein

What if we have been fighting disease the wrong way all along? In this powerful conversation, Dr. Matt Kaeberlein breaks down one of the most important shifts happening in modern medicine: targeting biological aging instead of chasing one disease at a time. Instead of waiting for heart disease, cancer, or dementia to show up, what if we could delay them all by addressing the root driver, aging biology itself? We explore: • The difference between lifespan and healthspan • Why most Americans are losing 15 to 20 healthy years • The truth about rapamycin and longevity science • The dangers of supplement overload and deceptive marketing • Why most consumer biological age tests are statistically meaningless • How AI and better biomarker tracking can reshape primary care • Why dogs may be the bridge to human longevity breakthroughs • How cities can realistically improve population health at scale This conversation is grounded in real science, not hype. It is about reclaiming your lost decades, becoming a partner in your healthcare, and investing in the one asset that matters most, your health. Dr. Kaeberlein will be speaking at the Oklahoma Health Summit on March 9th and 10th in Oklahoma City alongside other leading voices in longevity science, AI, and preventive healthcare. If you care about increasing healthspan, reducing chronic disease, and helping Oklahoma move from one of the least healthy states in the country to one of the healthiest, this is where it starts. 📍 March 9th and 10th 📍 Oklahoma City 🎟️ Register today: https://www.healthycityinitiative.com/ [https://www.healthycityinitiative.com/] Let’s build a healthier Oklahoma together.