In The Know With Nina
How are hormones, metabolism, and body composition shaping the way we care for patients during midlife, and why is so much of the conversation still filled with confusion and misinformation? In this episode of In the Know with Nina, Dr. Nina Crowley is joined by Disha Narang, Endocrinologist and Director of Obesity Medicine at Endeavor Health, for an evidence-based discussion on hormones, menopause, and obesity care. Together, they unpack the real role of key metabolic hormones—including thyroid, cortisol, insulin, estrogen, progesterone, and testosterone—and explain why popular phrases like “balancing hormones” often miss the clinical mark. Drawing from real-world patient care, the conversation explores how perimenopause and menopause drive changes in insulin resistance, visceral adiposity, and body composition—and why hormone replacement therapy (HRT) can improve symptoms and quality of life without being a weight-loss solution. Dr. Narang and Dr. Crowley also discuss when hormone testing is appropriate, why timing and context matter, and how combining HRT with evidence-based obesity treatments (including GLP-1 therapies) can support better outcomes for patients navigating midlife transitions. Throughout the episode, they highlight why body composition offers critical insight beyond the scale—especially when weight remains stable while muscle mass declines and visceral fat increases—and why collaborative, team-based care between endocrinology, OB-GYN, and obesity medicine is essential in this stage of life. Key Takeaways * Why hormones play a complex—but often oversimplified—role in midlife weight and metabolic health * How menopause contributes to insulin resistance and increased visceral adiposity * Why thyroid and cortisol frequently receive “undue credit” in weight discussions * When hormone testing is useful—and when it may create more confusion than clarity * What hormone replacement therapy (HRT) can and cannot do for weight management * How combining HRT with obesity treatments (including GLP-1 therapies) may improve patient outcomes * Why body composition helps reveal metabolic risk and progress that weight alone can’t show * How interdisciplinary care strengthens long-term, patient-centered midlife health management About my Guest Disha Narang, MD, is a quadruple board–certified physician in endocrinology, obesity medicine, internal medicine, and culinary medicine, and serves as Director of Obesity Medicine at Endeavor Health (NorthShore). She completed her undergraduate and medical training at Vanderbilt University, followed by an internal medicine residency and endocrinology fellowship at the University of Chicago. Dr. Narang specializes in the care of patients with diabetes and obesity and integrates culinary medicine into her practice, emphasizing the principle that food is medicine. How to Connect Linked in: https://www.linkedin.com/in/dishanarangmd/ Instagram: https://www.instagram.com/dishanarangmd
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