Kind of a Big Deal
What does it look like to leave a 20-year career not because you have to, but because you finally recognize you're ready? Angeliki is an MD-PhD with 35 years in medicine, the last two decades at Pfizer as a molecular medicine and pathology specialist. She was building AI-powered cancer prediction tools twenty years before "AI" became a buzzword, holds international patents with over 1,000 citations, and was named one of the 100 most influential women in biosciences out of 3,000 nominees. She also holds a master's in Arts and Literature from the Sorbonne... and somewhere in there, she got a skydiving degree and was accepted into NASA's Mars mission program. Now she's walking away from corporate entirely to build something of her own. Not because the work ran out, but because, as she puts it, the timing made the decision - not the decision itself. We talk about what it means to create your own room when nobody offers you a seat at the table, why joy is a choice instead of a circumstance, and what legacy looks like once you stop asking for permission. What You'll Learn ⭐ Why leaving a 20-year career can feel like relief instead of loss ⭐ How to create your own room when nobody offers you a seat at the table ⭐ Why joy is a choice, not a reaction to your circumstances ⭐ How to stop performing who you are and start building from who you are ⭐ How combining two unrelated disciplines can become your biggest professional advantage ⭐ What legacy actually means once you stop measuring it in money or titles Key Insights Pull the Chair and Sit at the Table In a male-dominated industry, Angeliki stopped waiting to be invited in. Her rule: if the room doesn't want you, build your own room - and welcome others into it. The Mind Is Like a Parachute Her theory: it works better when it's open. Pairing medicine with a master's in Arts and Literature from the Sorbonne taught her to translate complexity into something a room can actually act on. Joy Is a Choice, Not a Circumstance For Angeliki, joy isn't about whether life is going well. It's an internal practice you choose daily, based on your own values - regardless of what's happening around you. Legacy Isn't About What You Leave Behind It's about what you build, what it costs, and doing it anyway... so the people coming behind you know it's possible. Timestamps 00:00 Intro: meet Angeliki, the MD-PhD who almost went to Mars 03:00 A master's in Arts and Literature from the Sorbonne, and why it matters 04:00 Arriving in the US alone and building a career from zero 05:00 At three years old, she already knew she'd become a doctor 07:00 The skydiving degree and the NASA Mars mission acceptance 12:00 Her theory: the mind is like a parachute 17:00 Pull the chair and sit at the table — or build your own room 21:00 Why leaving corporate after 20 years felt like relief, not loss 24:00 Why she stopped waiting for the conditions to be right 40:00 Every decision that's true to who you are is a celebration 41:00 Joy is a choice, not a circumstance 50:00 What legacy really means Resources and Links Connect with Angeliki on LinkedIn [https://www.linkedin.com/in/angeliki-kotsianti/] Find host Kristin Belden on LinkedIn [https://www.linkedin.com/in/kristinbelden/] or at BeldenStrategies.com [https://www.beldenstrategies.com/] Sign up for Kristin's newsletter Big Deal Energy: BeldenStrategies.com/newsletter [https://www.beldenstrategies.com/newsletter] If this conversation resonated, share it with someone who needed to hear it - and consider leaving a review. It helps more awesome folks find these conversations. #careerchange #careerreinvention #womeninmidlife #leavingcorporate #womeninSTEM #AIinmedicine #executivecareerchange #purposedrivencareer #buildingyourownbusiness #midlifecareerpivot #womenleadership #legacy #over40 #kindofabigdeal #kristinbelden
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