Let's talk F*ng Cancer
In this episode, we're diving into Skin Cancer Awareness Month with a focus on melanoma and the science moving faster than ever. Colette brings an update on a treatment she covered in Episode 74, plus two more breakthroughs in melanoma care. Leah returns to a conversation we started last year with Dr. Michael Caney of CarThera, with new developments on their SonoCloud® technology. Leah discusses the advancments of the Sonocloud into its phse 3 trial. Julia covers the latest in bladder cancer research, including a brand-new drug developed right here in California. Elevate Society Review [https://elevatesociety.com/lets-talk-fng-cancer-podcast-review/] Resources & Clinical Trials • Melanoma Research Foundation Trial Finder: melanoma.org/clinical-trial-finder • ClinicalTrials.gov — search 'melanoma' or 'bladder cancer' for currently enrolling studies • UC Davis Bladder Cancer Trial: bcan.org/clinicaltrials/plz4-coated-paclitaxel-loaded-micelles-for-the-treatment-of-patients-with-recurrent-or-refractory-non-muscle-invasive-bladder-cancer • CarThera SONOBIRD Trial: sonobird.eu |NCT05902169 Sources Colette's Segments — Melanoma • American Cancer Society Cancer Statistics Report, Jan 2025: https://www.cancer.org [https://www.cancer.org] • Cancer Health — mRNA Vaccine 5-Year Follow-Up, Jan 2026: https://www.cancerhealth.com [https://www.cancerhealth.com] • ASCO 2025 Annual Meeting Abstracts: https://www.asco.org/meetings/2025 [https://www.asco.org/meetings/2025] • Melanoma Research Foundation 2025 ASCO Recap: https://melanoma.org [https://melanoma.org] • FDA Accelerated Approval — Lifileucel (Amtagvi), Feb 16, 2024: https://www.fda.gov [https://www.fda.gov] • Let's Talk F*ng Cancer — Ep. 74 (Lifileucel original coverage, May 2025): https://podcasts.apple.com/us/podcast/lets-talk-f-ng-cancer/id1697931310?i=1000708495074 [https://podcasts.apple.com/us/podcast/lets-talk-f-ng-cancer/id1697931310?i=1000708495074] Leah's Segment — CarThera • CarThera Research & Development Pipeline: https://carthera.eu/research-development/ [https://carthera.eu/research-development/] • SONOBIRD Phase 3 Trial — ClinicalTrials.gov NCT05902169: https://clinicaltrials.gov/study/NCT05902169 [https://clinicaltrials.gov/study/NCT05902169] • SONOKID Pediatric Trial — ClinicalTrials.gov NCT05293197: https://clinicaltrials.gov/ct2/show/NCT05293197 [https://clinicaltrials.gov/ct2/show/NCT05293197] • SONIMEL Melanoma Brain Metastases Trial — ClinicalTrials.gov NCT04021420: https://clinicaltrials.gov/ct2/show/NCT04021420 [https://clinicaltrials.gov/ct2/show/NCT04021420] Julia's Segment — Bladder Cancer • Cleveland Clinic — Bladder Cancer Overview: https://my.clevelandclinic.org/health/diseases/14326-bladder-cancer [https://my.clevelandclinic.org/health/diseases/14326-bladder-cancer] • Memorial Sloan Kettering — Bladder Cancer Treatments: https://www.mskcc.org/cancer-care/types/bladder#what-are-the-treatments-for-bladder-cancer- [https://www.mskcc.org/cancer-care/types/bladder#what-are-the-treatments-for-bladder-cancer-] • UC Davis Health — New Drug Offers Hope to Bladder Cancer Patients, Nov 2025: https://health.ucdavis.edu/news/headlines/new-drug-developed-at-uc-davis-offers-hope-to-bladder-cancer-patients/2025/11 [https://health.ucdavis.edu/news/headlines/new-drug-developed-at-uc-davis-offers-hope-to-bladder-cancer-patients/2025/11] • Michigan Institute of Urology — Bladder Cancer Without Bladder Removal: 2026 Options: https://www.michiganurology.com/bladder-cancer-without-bladder-removal-your-2026-options-blog/ [https://www.michiganurology.com/bladder-cancer-without-bladder-removal-your-2026-options-blog/] ⚠️ Medical Disclaimer The information shared in this episode is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider regarding any medical conditions, diagnoses, or treatment options.
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