Natural Medicines: Evidence in Practice - Clinical Guidance on Supplements & Integrative Therapies
Food, supplement, and medication interactions are more common—and more nuanced—than many clinicians realize. Everyday foods and supplements can quietly alter drug effectiveness or safety - and often go unrecognized in practice. Grapefruit juice, orange, juice, and green tea extract are just a few examples that may have more clinical significance than expected. In this episode, NatMed editors Jeff Langford, Andrea Stafford, and Kelly Daniels break down clinically relevant interactions using atorvastatin as a case study—and show how to apply a practical framework for identifying, interpreting, and managing these interactions at the point of care. Questions we answer in this episode: * Which common beverages, foods, and supplements interact with atorvastatin - and how do they affect the drug? * How do interactions differ between increased drug levels (toxicity risk) vs reduced drug effectiveness? * When should clinicians recommend avoidance vs timing adjustments vs monitoring? * How can clinicians identify interactions patients don’t think to mention in routine conversations? 🏷️ Our listeners can get 10% off a new or upgraded subscription with code natmed1026 at checkout [https://trchealthcare.com/product/natmed-pro/?trc_promo=natmed1026]. ****** NatMed / TRC Healthcare Editor Hosts: * Jeff Langford PharmD, BCPS, BCCP (Managing Clinical Editor) * Andrea Stafford, PharmD (Assistant Editor) * Kelly Daniels, BA (News Editor & Associate Content Manager) Guest: * Cathi Dennehy, PharmD, FCSHP (Health Sciences Professor of Clinical Pharmacy, UCSF School of Pharmacy) ****** CE Information: This podcast is sourced from the NatMed June 2026 Newsletter [https://naturalmedicines.therapeuticresearch.com/Content/nm/Newsletters/June2026]. To claim CE credit, subscribers should read the newsletter and click “Take the CE Quiz” link to take the quiz. Claim Credit [https://learning.therapeuticresearch.com/course/view.php?idnumber=26-176] ****** The clinical resources mentioned during the podcast are part of a subscription to NatMed: * 🌱 NatMed Pro [https://naturalmedicines.therapeuticresearch.com/Home/ND] * 💊 TRC Healthcare [https://trchealthcare.com/product/natmed-pro/] * Newsletter [https://naturalmedicines.therapeuticresearch.com/Content/NewsletterBrowse] * Interaction Checker [https://naturalmedicines.therapeuticresearch.com/Tools/InteractionChecker] * Infographic [https://naturalmedicines.therapeuticresearch.com/-/media/Site/NatMed-Pro/Podcast-Ep106_Atorvastatin-Interactions.ashx] * Monograph: Grapefruit [https://naturalmedicines.therapeuticresearch.com/IngredientsTherapiesMonographs/Pro?id=946] * Monograph: Green Tea [https://naturalmedicines.therapeuticresearch.com/IngredientsTherapiesMonographs/Pro?id=960] * Monograph: Orange Juice [https://naturalmedicines.therapeuticresearch.com/IngredientsTherapiesMonographs/Pro?id=908] ****** Don’t miss out! Subscribe today to stay ahead with trusted, practical insights and tools. ****** Send us Fan Mail [https://www.buzzsprout.com/2549833/fan_mail/new] Email us: ContactUs@trchealthcare.com [ContactUs@trchealthcare.com] The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Natural Medicines: Evidence in Practice is a production of TRC Healthcare.
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