The Nicolas Procel Podcast
Dr. Juan Carlos Marvizón, (pseudonym Hermes Solenzol) is a retired neuroscientist and expert in pain physiology, as well as a former member of the UCLA Brain Research Institute. He is also an author of various... romance books, and has a blog about various topics including science, philosophy, and more. In this episode, Dr. Solenzol and I talk about some of the mistakes and oversimplifications made by Dr. Andrew Huberman and Dr. Anna Lembke. We also talk about all things dopamine, including its role in pleasure, its role in motivation/wanting, the neurobiology of the "dopamine reward pathway," the pleasure-pain balance being "bullshit," habituation, addiction, compulsive behavior, drugs' interactions with the brain, pornography, gambling, and more. 0:00 Intro 0:47 How Dr. Huberman & Dr. Lembke Are Wrong About Dopamine 5:13 Can Non-Drug Stimuli (e.g. Behavior) Be Addictive? 9:54 Does Dopamine Cause Pleasure? Or Just Desire? 15:31 The Neurobiology of the Dopamine (Mesolimbic) Reward Pathway 17:53 How Drugs Interact With Dopamine Release & the Brain 19:13 A Simpler Explanation of Dopamine, the Reward Pathway, & Drug Interactions With the Brain (Trying to Dispel Confusion) 22:20 Dopamine Peaks & Baselines 24:23 What Does Dopamine Do, and What Does It Make Us Feel? 28:03 Does Dopamine Make Us Desire & Crave? 29:04 Dopamine Receptors (Very Important for Understanding Dopamine & Its Effects) 37:01 Dopamine Is the Molecule of Change 37:46 The Neurobiology of Addiction 46:56 Compulsive Behaviors; Too Much Dopamine 50:18 Dr. Huberman is Wrong: Supplementing L-Tyrosine is Useless for Dopamine 52:02 L-Dopa Supplementation, Problems With L-Dopa 56:06 Neurobiological & Other Differences Between Addiction & Compulsion 1:02:49 There Is No Such Thing As Too Much Pleasure 1:04:29 Sources of Craving 1:08:58 Why Some People Seek Pain 1:11:51 What's Behind Compulsive Gambling? 1:14:27 Why Is Pornography More Compulsive Than Sex? 1:17:25 "The Pleasure-Pain Balance is Bullshit" 1:22:56 Does "High-Dopamine" Behavior Lead to Less Pleasure? 1:30:29 Does Habituation Affect All Pleasure, or Is It Just Local? 1:32:55 Combatting Habituation With Mindfulness 1:35:16 How Can We Maximize Reward and Minimize the Cost? 1:41:52 How Do We Enjoy Lots of Pleasure While Avoid Habituation, Tolerance, & Other Dark Sides of Pleasure? 1:45:10 A Wandering Mind Is an Unhappy Mind 1:48:48 Where to Find Dr. Solenzol FIND DR. SOLENZOL Dr. Solenzol's blog – https://www.hermessolenzol.com/en Dr. Solenzol's Medium – https://medium.com/@hermessolenzol Dr. Solenzol's Substack – https://scienceandmeaning.substack.com/ DR. SOLENZOL'S BOOKS Games of Love and Kink – https://amzn.to/47DhgV9 Juegos de amor y dolor – https://amzn.to/4mwbBVI Cecilia desencadenada – https://amzn.to/45x0qGk Amores Imposibles – https://amzn.to/45MhO8L La tribu de Cecilia – https://amzn.to/4fJ31A8 Para volverte loca – https://amzn.to/45KDi62 BOOKS MENTIONED Anna Lembke's "Dopamine Nation" – https://amzn.to/45BgsgQ David Linden's "The Compass of Pleasure" – https://amzn.to/4lxSXeB Daniel Lieberman's "The Molecule of More" – https://amzn.to/3Ve4Z22 Watch on YouTube: https://youtu.be/5X5PgX0qe8M
13 episodios
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