Solving Chronic Pain and Long COVID: The Mind-Body Connection with Dr. Michael Donnino

Solving Chronic Pain and Long COVID: The Mind-Body Connection with Dr. Michael Donnino

In this episode of Multitudes [https://multitudes.weisser.io/], Harvard Medical School Professor Dr. Michael Donnino shares groundbreaking research on the mind-body connection in treating back pain, long COVID, and other chronic conditions. Drawing from his personal experience with debilitating back pain and extensive clinical research, Dr. Donnino reveals how the brain can both create and resolve physical symptoms, and why traditional treatments often miss the mark. Key topics discussed: • How Dr. Donnino's own back pain led to this research • The science behind mind-body healing • Why pain can persist even when tests show nothing wrong • The surprising connection between chronic pain and Long COVID. • Results from clinical trials showing 64% of patients becoming pain-free • New research on migraines and other conditions • The role of fear and stress in physical symptoms Links: 📝 Read the transcript: https://multitudes.weisser.io [https://multitudes.weisser.io] Timeline: 00:00 – Introduction & Julian's Back Pain Story 02:30 – Dr. Donnino's Medical Background 05:20 – Dr Donnino's Experience with Back Pain 09:00 – Discovery of Dr. Sarno's Work 13:00 – Transition to Mind-Body Research 17:40 – Developing Clinical Trials 24:00 – Understanding Mind-Body Connection 30:00 – Success Rates & Treatment Effects 41:00 – Long COVID Research and Treatment 50:00 – Patient Skepticism & Treatment Acceptance 56:00 – Breaking Conditioned Responses 1:06:00 – Treatment Methodology 1:19:00 – Current Research & Future Directions 1:25:00 – Concluding Thoughts #ChronicPain #LongCOVID #MindBody #Health #Medicine #Research #BackPain #Healing #Sarno Get full access to Weisser's Multitudes at multitudes.weisser.io/subscribe [https://multitudes.weisser.io/subscribe?utm_medium=podcast&utm_campaign=CTA_4]

86% of Food Contained Plastic: Inside PlasticList's Groundbreaking Study with Yaroslav Shipilov

"You can just do things. That's the biggest truth that I think the world runs on. You can just follow your curiosity." This episode kicks off my new show Multitudes, where I highlight ideas and people worth exploring further. I don’t charge money for the show but you can support by subscribing on YouTube [https://www.youtube.com/@weissersmultitudes?sub_confirmation=1], Apple, or Spotify [https://open.spotify.com/show/6mjTV2Z6KWBajTHh2nP0Hl] and, if you feel inclined, leave a review or thumbs up. Last week, PlasticList [https://www.plasticlist.org/] released a groundbreaking report [https://www.plasticlist.org/report] showing that 86% of tested foods in the Bay Area contain plastic chemicals. I sat down with Yaroslav Shipilov [https://x.com/TheSlavant], one of the four people behind this ambitious project, to discuss not just the concerning findings, but also what it takes to pursue an unusual and impactful project like this. The origin story of PlasticList exemplifies how great projects can start: Yaroslav saw Nat Friedman's tweet [https://x.com/natfriedman/status/1789287484515659896] about wanting to test Bay Area foods for plastic chemicals and, instead of just expressing interest, he built a prototype website in an afternoon. He kept iterating on it for a week without any response. Then, 20 minutes after launching an improved version with voting features, he got a DM from Nat: "Yo, what are you doing? You want to work on this?" What was supposed to be a few weeks of work turned into a six-month journey involving: * Reaching out to over 100 labs before finding the right one * Shopping for hundreds of food samples across the Bay Area * Testing everything from modern snacks to 80-year-old Ghirardelli chocolate * Making surprising discoveries about which foods contained plastic chemicals Some of the most fascinating findings weren't just about current foods - they also tested historical samples from as far back as the 1940s. While older foods also contained plastic chemicals, the types were different: older samples had more traditional phthalates, while newer foods showed higher levels of phthalate substitutes. The conversation covers both the technical aspects of the project and the human elements of building something ambitious. As Yaroslav puts it: "You can just do things. That's the biggest truth that I think the world runs on. You can just follow your curiosity." What stands out most to me about PlasticList is how it demonstrates that important work doesn't always require traditional institutions or massive resources - sometimes it just takes curiosity and the courage to start building. Links * Full episode transcript [https://weisser.io/transcripts/plasticlist] * PlasticList’s report [https://www.plasticlist.org/report] * Yaroslav [https://x.com/TheSlavant] and Julian [https://x.com/julianweisser] on X Are you exploring starting a company? I started ODF [https://joinodf.com] to help people find the missing pieces — who they might build with, what they might build, etc. We’re over 5 years in and have helped over 1,000 startups launch — check out our top companies list [https://www.joinodf.com/top-companies-2024]. We’re launching our 24th ODF cohort in SF in late February. Learn more [http://joinodf.com]and apply. Are you looking for funding for an ambitious project like PlasticList? Merge [https://merge.club] is the place for microgrants online. We built a community for people work on ambitious projects and a microgrant guide [https://merge.club/guide] featuring video reviews, examples of successful applications, and more, that has already helped people raise >$100k in non-dilutive capital for their projects. P.S. Hit reply if you enjoyed this or have thoughts for future episodes. Get full access to Weisser's Multitudes at multitudes.weisser.io/subscribe [https://multitudes.weisser.io/subscribe?utm_medium=podcast&utm_campaign=CTA_4]