JAMA Clinical Reviews

Survivors of Cyanotic Congenital Heart Disease

Cyanotic congenital heart diseases occur in approximately 0.2% of live births in the US, but survival to adulthood is common with current surgical interventions. JAMA Associate Editor David Simel, MD, MHS, speaks with author Michael Landzberg, MD, who coauthored a recent review in JAMA on this topic. Related Content: * Survivors of Cyanotic Congenital Heart Disease [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.8806?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links]

Point-of-Care Ultrasound for the Diagnosis of Pneumonia: A Review

Community-acquired pneumonia (CAP) accounts for 1.4 million emergency department visits and 740 000 hospitalizations annually in the US. Author Andre Kumar, MD, MEd, of Stanford University School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the use of point-of-care ultrasound for diagnosis of CAP. Related Content: * Point-of-Care Ultrasound for the Diagnosis of Pneumonia [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.4782?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Bedside Lung Ultrasound in Emergency (BLUE) for Evaluation of Dyspnea [https://edhub.ama-assn.org/jn-learning/video-player/10.1001/jama.2026.6399?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links]

Cesarean Delivery on Request

Cesarean delivery on maternal request requires individualized counseling. Reduced risks of pelvic floor disorders should be weighed against surgical risks and future risks including abnormal placentation. Author Marianna Alperin, MD, MS, from UC San Diego School of Medicine, discusses this and more with JAMA Deputy Editor Linda Brubaker, MD. Related Content: * Cesarean Delivery on Maternal Request [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.26633?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Cesarean Delivery—Reply [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.6781?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Cesarean Delivery [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.6779?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links]

Diet and Exercise Recommendations for Patients Taking GLP-1 Receptor Agonists

The GLP-1 receptor agonists reduce appetite and greatly facilitate weight loss. Robert Kushner, MD, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss appropriate diet and exercise recommendations for patients receiving GLP-1 receptor agonists for weight loss. Related Content: * Lifestyle Modification and Incretin-Based Therapy for Obesity [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.4106?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * The Conundrum of Exercise for Weight Management in the GLP-1 Receptor Agonist Era [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.5537?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links]

An Overview of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS), which affects about 25 000 individuals in the US, causes progressive weakness but has varied presentations. Several FDA-approved medications are now available for ALS. Author John Ravits, MD, of UC San Diego School of Medicine joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of ALS. Related Content: * Amyotrophic Lateral Sclerosis [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2026.6385?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Pridopidine in Amyotrophic Lateral Sclerosis [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.26429?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * What Is Amyotrophic Lateral Sclerosis? [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.19305?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * CNM-Au8 in Amyotrophic Lateral Sclerosis [https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.27643?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Safety and Efficacy of PrimeC in Amyotrophic Lateral Sclerosis [https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2026.0230?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links] * Traumatic Brain Injury and Risk of Amyotrophic Lateral Sclerosis [https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.35119?utm_source=podcast_platforms&utm_medium=referral&utm_campaign=related_article_links]