Inside Pharma Leadership

Ep6 - Overcoming Imposter Syndrome in Finance with Karthik Sriram

31 min · 16. Apr. 2026
Episode Ep6 - Overcoming Imposter Syndrome in Finance with Karthik Sriram Cover

Beschreibung

Karthik Sriram joins me to share how biotech finance leaders balance science, strategy, and capital to drive innovation. From his journey into the industry to raising over $800M, we unpack what it really takes to fund and scale life sciences companies—and why emotional intelligence is just as critical as financial expertise. ---------------------------------------- MEET THE GUEST Karthik Sriram is a biotech finance executive currently leading Financial Planning & Analysis at Parabilis Medicines. With a background in biomedical engineering and an MBA from Wharton, he brings a unique ability to translate complex science into business strategy. He has helped secure more than $800M in capital, supporting clinical development, extending cash runway, and positioning companies for growth and partnerships. ---------------------------------------- KEY TAKEAWAYS * Career paths aren’t linear—unexpected experiences often shape long-term direction * Emotional intelligence is critical in finance, especially when influencing decisions and budgets * Strong relationships and trust are essential to doing the job effectively * OPEX vs. CAPEX decisions are foundational in biotech and directly impact scalability * Raising capital requires honesty, clarity, and deep knowledge of your numbers * Understanding the science—even at a high level—builds credibility with investors * AI is accelerating drug development, especially in chemistry and early modeling * The future of finance teams in biotech may be smaller, more automated, and AI-driven * Early-stage companies face real barriers in adopting tools due to cost structures * Flexibility—not fully remote or fully in-office—is the most effective operating model ---------------------------------------- CONNECT WITH KARTHIK LinkedIn: https://www.linkedin.com/in/karthiksriram [https://www.linkedin.com/in/karthiksriram]X (Twitter): https://x.com/KarthikSriram_ [https://x.com/KarthikSriram_] Email: ksriram@parabilismed.com [ksriram@parabilismed.com] Connect with Keith LinkedIn: https://www.linkedin.com/in/keithawillis/ [https://www.linkedin.com/in/keithawillis/] Email: kwillis@coremanagementtraining.com [kwillis@coremanagementtraining.com]

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Episode Ep10 - The Black Box of Drug Discovery with David White Cover

Ep10 - The Black Box of Drug Discovery with David White

In Episode 10 of Inside Pharma Leadership, I sit down with David White to explore the journey from scientific discovery to real-world patient impact. From drug development and commercialization to venture capital and biotech innovation, this episode dives into the business and science behind bringing life-changing therapies to market. Meet the Guest David White is a biopharma executive with more than 20 years of experience in drug discovery, strategic partnerships, and platform development. As SVP of Drug Discovery at ProteinQure, David has helped bridge the gap between cutting-edge science and commercially viable therapies across biotech, pharma, and venture-backed organizations. Key Takeaways * Value creation and resource management in biopharma * Decision-making based on unmet medical needs and landscape analysis * The black box of early drug discovery and its excitement * Transition from early discovery to commercialization with Target Product Profiles * Drug repurposing and repositioning strategies * Remote work and technology in drug discovery * Challenges of raising capital in biotech * Building a strong scientific advisory board for investment * Balancing scientific innovation with business strategy * Time as a critical resource in drug development Chapters * 00:00 Introduction to Biopharma Leadership * 01:13 The Journey of a Biopharma Leader * 02:22 Value Creation in Drug Development * 04:05 The Shift in Drug Discovery Dynamics * 06:16 The Excitement of Early Drug Development * 08:34 Transitioning from Discovery to Commercialization * 12:15 The Process of Drug Repurposing * 17:54 Business Aspects of Drug Development * 21:24 Challenges in Raising Capital * 26:14 Navigating Capital and Time Constraints * 27:59 Closing Thoughts on Drug Discovery Connect with David White * LinkedIn: https://www.linkedin.com/in/david-white-pharmaceuticals-biopharmaceuticals/ [https://www.linkedin.com/in/david-white-pharmaceuticals-biopharmaceuticals/] * Email: david@proteinqure.com [david@proteinqure.com] Connect with Keith Willis & Inside Pharma Leadership * Instagram: @coachtoachieve * LinkedIn: https://www.linkedin.com/in/keithawillis/ [https://www.linkedin.com/in/keithawillis/]  * Email: kwillis@coremanagementtraining.com [kwillis@coremanagementtraining.com] * Apple Podcast: https://podcasts.apple.com/us/podcast/inside-pharma-leadership/id1882373713 [https://podcasts.apple.com/us/podcast/inside-pharma-leadership/id1882373713]

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Episode Ep6 - Overcoming Imposter Syndrome in Finance with Karthik Sriram Cover

Ep6 - Overcoming Imposter Syndrome in Finance with Karthik Sriram

Karthik Sriram joins me to share how biotech finance leaders balance science, strategy, and capital to drive innovation. From his journey into the industry to raising over $800M, we unpack what it really takes to fund and scale life sciences companies—and why emotional intelligence is just as critical as financial expertise. ---------------------------------------- MEET THE GUEST Karthik Sriram is a biotech finance executive currently leading Financial Planning & Analysis at Parabilis Medicines. With a background in biomedical engineering and an MBA from Wharton, he brings a unique ability to translate complex science into business strategy. He has helped secure more than $800M in capital, supporting clinical development, extending cash runway, and positioning companies for growth and partnerships. ---------------------------------------- KEY TAKEAWAYS * Career paths aren’t linear—unexpected experiences often shape long-term direction * Emotional intelligence is critical in finance, especially when influencing decisions and budgets * Strong relationships and trust are essential to doing the job effectively * OPEX vs. CAPEX decisions are foundational in biotech and directly impact scalability * Raising capital requires honesty, clarity, and deep knowledge of your numbers * Understanding the science—even at a high level—builds credibility with investors * AI is accelerating drug development, especially in chemistry and early modeling * The future of finance teams in biotech may be smaller, more automated, and AI-driven * Early-stage companies face real barriers in adopting tools due to cost structures * Flexibility—not fully remote or fully in-office—is the most effective operating model ---------------------------------------- CONNECT WITH KARTHIK LinkedIn: https://www.linkedin.com/in/karthiksriram [https://www.linkedin.com/in/karthiksriram]X (Twitter): https://x.com/KarthikSriram_ [https://x.com/KarthikSriram_] Email: ksriram@parabilismed.com [ksriram@parabilismed.com] Connect with Keith LinkedIn: https://www.linkedin.com/in/keithawillis/ [https://www.linkedin.com/in/keithawillis/] Email: kwillis@coremanagementtraining.com [kwillis@coremanagementtraining.com]

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