Just ONE driving factor? What's Really Behind Brain Fog, Fatigue & Dementia?

The Truth About Wheat: Why Gluten Isn’t the Problem

My guest today is Bob Quinn - a true pioneer of ancient, organic grains. In this rare opportunity to meet with him in his 80th year, en route to Italy, recorded in the car on the way to the airport, we unpack the whole story from the origins of the organic, wholegrain movement in the 80’s, up to now. He explains why it isn't gluten that’s causing so many people to react to wheat (other than coeliacs), what’s really happening, and what needs to happen to our food supply. His hat contains Kamut Khorosan grain - mine is made from our alpacas.   Find out more about food intolerances [https://www.patrickholford.com/topic/allergies/] on my website or read my book Hidden Food Allergies. [https://www.holfordnutrition.com/product/hidden-food-allergies-patrick-holford/]

Just ONE driving factor? What's Really Behind Brain Fog, Fatigue & Dementia?

My guest today, Professor Robert Lustig - neuroendocrinologist and Professor Emeritus from the University of California San Francisco (UCSF), world-renowned for unravelling how sugar, fructose and ultra-processed foods degenerate health - proposes that there is one messed up underlying process that almost all contributors to cognitive decline compound. This is an overload of reactive oxygen species (ROS), or oxidants, due to a four step dance that grinds healthy metabolism to a halt. If this is right - and I think it is - this means there are four avenues open to us all to prevent the damping down of energy, both in the brain, but also in the body. Find out how in this podcast. For more about brain health see my books Upgrade Your Brain [https://www.holfordnutrition.com/product/uyb-book/] and Alzheimer's: Prevention is the Cure [https://www.holfordnutrition.com/product/apc/] and Brain Health [https://www.patrickholford.com/topic/brain-health-memory/] topic on my website.  Take part in Alzheimer's Prevention Day on Tuesday 19 May. Take the 3 minute test [https://ffb-upgradedcft.org/apc] and learn more [https://www.alzheimersprevention.info/].

Stimulate Your Mind to Stop Decline

My guest is Dr Tommy Wood, who is Associate Professor of Neuroscience and Paediatrics at the University of Washington. He also heads research at the Food for the Brain Foundation and brain trains professional athletes including Olympians and Formula 1 racing drivers. With a Bachelor’s degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in Physiology and Neuroscience from the University of Oslo, he has approached how to optimise and recover your brain - from all sides. He is also co-founder of the British Society for Lifestyle Medicine.   Here we talk about his new book 'The Stimulated Mind [https://www.amazon.co.uk/Stimulated-Mind-Breakthrough-Future-Proof-Dementia/dp/1785045148?crid=2ACV0GN87M7R4&dib=eyJ2IjoiMSJ9.OYh9EqKTpU4nvuMwXge45EuzqhmNu70etPDbU2nGnyclD3FzZv6Ys8GCVy7H-LK9zBSJeUlQvq7FetAOI9PrfkEpz2tSStNHfk8JsA1AS7kl23UqxCEJ3Qnz9p4E3ab3s-f6fD-cH3NNH3lKZT5kmStXZDx-l90j_0yXCg9Y33btc9p8UyHSvK29F38RQCkWxl8y4XYepii2n5fI1NkxTRfn2XCCWx29E-egJLqkw8U.KDHukxaat-NZoqifLasixz4rCLHnzSD0RHXOw0gRPLY&dib_tag=se&keywords=tommy+wood&qid=1769438970&sprefix=tommy+wood,aps,115&sr=8-1&linkCode=sl2&tag=foodfortheb01-21&linkId=eee4f7a737169f9a7c0f66e8bbf7afba&ref_=as_li_ss_tl]' - just out - and how to future proof your brain.     For more on brain health, visit my website [https://www.patrickholford.com/topic/brain-health-memory/]and read my books Upgrade Your Brain [https://www.holfordnutrition.com/product/uyb-book/] and Alzheimer's Prevention is the Cure [https://www.holfordnutrition.com/product/apc/].

How I Reversed Pre-Dementia

In today’s podcast, my guest is Dr Bill Wilson, a front-line physician who practiced medicine in Minnesota and Massachusetts for over 40 years. Three years ago, Dr Wilson was diagnosed with mild cognitive impairment - often described as pre-dementia. Instead of accepting it as inevitable, he took action. The result? He reversed it. Now, drawing on both his medical background and personal experience, Dr. Wilson has developed a sharp, highly practical focus on neuroscience. In this conversation, he breaks down exactly what helped restore his cognitive function - and, just as importantly, what truly matters for anyone on the slippery slope of cognitive decline. If brain health is something you—or someone you love—are thinking about, this episode is essential listening.   For more information read my book 'Upgrade Your Brain [https://www.holfordnutrition.com/product/uyb-book/]' and visit the Alzheimer's and Dementia [https://www.patrickholford.com/topic/alzheimers-and-dementia/] Topic on my website.  Take the Food for the Brain Cognitive Function Test. [https://foodforthebrain.org/the-cognitive-function-test/]

How To Be Healthy in 2026

Happy New Year! As we head into 2026, what actually matters when it comes to protecting your health - and what’s just noise? In this month’s podcast, I share my top health predictions for the year ahead and the habits truly worth adding to your New Year Resolutions. We go behind the headlines to unpack health politics, misinformation, and some uncomfortable truths - from vaccines and new Alzheimer’s drugs to how nutritional medicine is really moving forward. In this episode, you’ll discover: * The five most important actions you can take to reduce your risk of cancer * Why vitamin C, when used correctly, may be more effective than a flu vaccine * The latest breakthroughs in antioxidants and anti-ageing science—including one powerful antioxidant you may not have heard of If your goal this year is clarity, resilience, and long-term health - not fads or fear- this episode will give you a strong head start. Wishing you a happy, healthy, and well-informed New Year. Do listen in. Visit my website www.patrickholford.com [http://www.patrickholford.com] and sign up to my E-News to stay informed.