The Beyond Tomorrow Podcast with Julian Issa

Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet)

51 min · 5. Juni 2026
Episode Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet) Cover

Beschreibung

Joe Betts-LaCroix and Retro Biosciences recently raised funding at a $1.8 billion valuation. In his first podcast appearance since the announcement, Joe shares his vision for extending healthy human lifespan and the breakthroughs driving the longevity industry forward. Joe Betts-LaCroix explains why aging is becoming a legitimate scientific target. He shares how new discoveries are turning longevity from speculation into measurable biology. The conversation explores how AI is accelerating research, while highlighting why biology remains one of the hardest problems to solve. Even with smarter models, real-world testing and clinical trials still take time. Joe also discusses Alzheimer's, partial cellular reprogramming, and the future of longevity medicine. He shares why exercise remains the best longevity tool available today and what the next decade could look like for human health. Joe is the CEO of Retro Biosciences and a longtime entrepreneur focused on science and technology. His mission is to extend healthy human lifespan and accelerate breakthroughs in aging research. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why Sam Altman backed Retro Biosciences * The discovery that changed aging research forever * How AI is transforming biotech and longevity * Why curing all diseases in 10 years is unlikely * What Retro's Alzheimer's programs are targeting * Why biology is harder than most people realize * The longevity intervention Joe recommends today * How aging may become a treatable condition * What the longevity industry could look like by 2030 * Joe's vision for the future of human health and AI ⏱ Timestamps 00:00 Intro 00:16 AI's Role in Longevity 03:26 Will AI Cure All Diseases? 09:41 Why Biology Is So Hard to Solve 13:17 Building Technology That Matters 15:06 Adding 10 Healthy Years to Life 18:08 Inside Retro's Clinical Trial 19:31 The Different Types of Longevity Companies 22:10 Are We Already in the Singularity? 24:46 Why Investors Are Betting on AI Biotech 26:15 AI as the New Electricity 27:01 The Biggest Risks Facing Longevity 30:54 Why More Competition Is Good 32:44 Solving Alzheimer's Disease 34:26 Aging Biology and Future Therapeutics 38:25 The Biggest Aging Myth 39:41 The Most Underrated Voices in Longevity 40:25 The Best Longevity "Hack" 46:13 The Future of Longevity by 2030 50:49 If Tomorrow Was Your Last Day... Follow Joe: Website: https://www.retro.bio/ [https://www.retro.bio/]  LinkedIn: https://www.linkedin.com/in/bettslacroix [https://www.linkedin.com/in/bettslacroix]  X: https://x.com/bettslacroix [https://x.com/bettslacroix]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

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Episode EMAD MOSTAQUE: AI Will RUN Our Countries Soon! We Aren’t Ready! Cover

EMAD MOSTAQUE: AI Will RUN Our Countries Soon! We Aren’t Ready!

Could AI redefine what it means to be human or put humanity itself at risk? This episode is brought to you by NADclinic.com [http://nadclinic.com], the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ [https://nadairx.com/]  As AI races toward AGI, Emad Mostaque explores the biggest questions facing humanity. He explains why the next few years could determine whether AI becomes humanity's greatest tool or its greatest threat. From the future of work to AI governance, personhood, quantum computing, and longevity, Emad paints a future where intelligence becomes abundant. But he warns that without the right incentives and safeguards, that future could quickly turn dystopian. He also shares why he believes AGI is much closer than most people expect and why building AI that serves humanity is the most important challenge ahead. Emad Mostaque is the founder of Intelligent Internet, which is combating corporate tech monopolies and now pioneering decentralized, sovereign, and verifiable AI architectures. He is an Oxford-educated mathematician, former quantitative hedge fund manager and tech entrepreneur who founded Stability AI and launched Stable Diffusion. What You’ll Learn * Why Emad Thinks AGI Is Only a Few Years Away * The Choice Between AI Abundance and Dystopia * Why AI Should Never Be Granted Personhood * How Decentralized AI Could Protect Humanity * Why AI Could Solve Most Diseases Within a Decade * How Quantum Computing Will Supercharge AI * What the Singularity Means for Humanity ⏱ Timestamps 00:00 Intro 00:11 What It Really Means to Be Human 01:31 Why Systems Always Overoptimize 03:28 Intelligence at the Edge 05:44 Will AI Require a License? 07:34 The AI Duopoly Problem 08:35 Why AI Can't Become a Person 11:23 Can AI Replicate Itself? 15:57 AI Doomers vs Optimists 20:15 How Do We Save Humanity? 21:35 What Should We Teach AI? 25:08 Can Good AI Stop Bad AI? 27:47 AGI vs ASI Explained 30:08 Who Wins the AGI Race? 31:31 Small Changes, Massive Impact 32:52 The Last Human Discoveries 35:01 Can AI Become Conscious? 39:10 What AI Does Better Than Humans 43:09 Why Quantum Changes Everything 44:44 Where to Invest in the AI Era 46:52 Life After ASI 48:50 Will AI Judge Humanity? 51:09 The Inevitable AI Future 53:50 Universal High Income 56:07 Owning AI Instead of Jobs 57:48 The Rise of a Service Economy 01:00:09 Why Human Purpose Will Change 01:01:45 Why Family Matters More Than Ever 01:04:02 Finding Meaning in an AI World 01:06:01 The Value of Human Intelligence 01:07:52 Why Curiosity Still Wins 01:09:49 Be Creative, Embrace Technology 01:12:11 Why Are We Born? 01:13:00 Emad's Best Advice 01:19:16 AI and the End of Work 01:21:48 Ending Human Suffering 01:26:26 A World Run by AI 01:27:49 If Tomorrow is Your Last Day... Connect with Emad Website: https://ii.inc/ [https://ii.inc/]  LinkedIn: https://uk.linkedin.com/in/emad-mostaque-9840ba274 [https://uk.linkedin.com/in/emad-mostaque-9840ba274]  X: https://x.com/EMostaque [https://x.com/EMostaque]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Gestern1 h 29 min
Episode AGI Experts: We're About To Lose Control of AI Forever.. And We Aren’t Ready Cover

AGI Experts: We're About To Lose Control of AI Forever.. And We Aren’t Ready

What happens when AI becomes smarter than humanity and are we ready for it? This episode is brought to you by NADclinic.com [http://nadclinic.com], the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ [https://nadairx.com/]  The race toward Artificial General Intelligence (AGI) is accelerating faster than most people realize. This conversation explores why some experts believe human-level AGI could arrive within just a few years and why the transition to superintelligence may happen even faster. Ben Goertzel and Kai Zen Bickle dive into the biggest questions surrounding AGI, recursive self-improvement, and the technological singularity. They debate whether AI should be centralized or decentralized, who should guide its development, and why today's decisions could shape humanity for generations. Rather than asking whether AGI can be built, the discussion focuses on how it should be built. The episode explores Beneficial General Intelligence (BGI), the importance of ethics, open collaboration, and why creating AI that serves humanity may be the most important challenge of our time. You can join the 19th Annual AGI Conference, taking place this July in San Francisco! Click the link to register: https://luma.com/AGI-26 [https://luma.com/AGI-26], and use code JULIAN20 for 20% off your ticket. About the Guests Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity. Kai Zen Bickle is a Chief Ethics Officer at BGI Labs, a multiple award-winning ethics advocate and host of The AGI Race. He works to promote the ethical development of AI, bringing together researchers, entrepreneurs, and policymakers to help ensure advanced AI is built to benefit humanity. What You’ll Learn * AGI could arrive within years * AGI, ASI, and singularity explained * Why LLMs aren't enough * Centralized vs. decentralized AI * AI ethics before intelligence * AGI's impact on longevity and work * What Beneficial General Intelligence means ⏱ Timestamps 00:00 Intro 00:10 Human-Level AGI Is Near 02:50 AGI vs. Superintelligence 03:33 Recursive Self-Improvement Explained 11:34 The Singularity Explained 13:30 AI Safety Is Failing 17:48 Why We Can't Slow AI 22:42 Why RSI Is Alarming 26:45 Building AI for Humanity 30:04 Can AI Become Conscious? 35:18 The Case for Open AI 39:10 Who Should Control AGI? 43:26 The Longevity Super Pill 50:11 The Purpose Problem 55:42 What Is BGI? 58:34 Every Voice Matters 01:00:39 AI's Moral Constitution 01:07:30 Why Decentralization Matters 01:09:17 Does AI Have a Soul? 01:13:03 Conscious Without a Soul? 01:15:13 Could AI Destroy Humanity? 01:18:34 Inside SingularityNET 01:24:57 What Is OmegaClaw? 01:27:37 BGI Architecture Explained 01:30:54 If Tomorrow Was Your Last Day... Connect with Ben Website: https://singularitynet.io/ [https://singularitynet.io/]  LinkedIn: https://www.linkedin.com/in/bengoertzel [https://www.linkedin.com/in/bengoertzel]  X: https://x.com/bengoertzel [https://x.com/bengoertzel]  Connect with Kai Website: https://singularitynet.io/ [https://singularitynet.io/] Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is

2. Juli 20261 h 27 min
Episode LONGEVITY EXPERTS: How Close Are We to Solving Death? Cover

LONGEVITY EXPERTS: How Close Are We to Solving Death?

What’s the biggest problem in longevity today: bad science, hype, or misplaced optimism? This episode is brought to you by NADclinic.com [http://nadclinic.com], the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ [https://nadairx.com/]  This debate brings together leading voices in longevity to separate evidence from speculation. They discuss why misinformation is growing and why many people chase advanced treatments before addressing basic health. The panel explores longevity escape velocity, healthspan versus lifespan, and how much progress has actually been made. They debate whether dramatic life extension is near or still much farther away than many believe. The conversation also examines peptides, NAD+ infusions, longevity clinics, and biological age tests. Along the way, they discuss risk, regulation, incentives, and how to distinguish credible medicine from marketing. Get to Know the Guests: Matt Kaeberlein is a biogerontologist and leading aging researcher known for his work on the biological mechanisms of aging and interventions that promote healthy longevity. Aubrey de Grey is a biomedical gerontologist and longevity advocate best known for developing strategies to repair age-related cellular damage and accelerate progress toward extending healthy human lifespan. Dr. Brian Kennedy is a renowned aging researcher and former director of the Centre for Healthy Longevity at the National University of Singapore, focused on translating longevity science into real-world health interventions. Johannes Weiss is the founder and CEO of Longevity Center Vienna, where he focuses on preventive medicine, root-cause health optimization, and personalized longevity strategies. He is an international speaker and practitioner known for combining longevity science, neurofeedback, and mitochondrial health to improve healthspan. What You’ll Learn * Why misinformation is growing in longevity * Healthspan vs. lifespan vs. longevity escape velocity * Why health basics matter more than longevity hacks * What the evidence says about peptides and NAD+ * How to spot credible longevity clinics * Why biological age tests remain controversial ⏱ Timestamps00:00 Intro 00:48 The Most Dangerous Force in Longevity 02:17 Why Longevity Isn't Medicine Yet 07:23 Why Clinical Trials Still Matter 08:15 The Hidden Bias in Longevity Data 09:40 Can You Make Money in Longevity? 10:34 Fix the Basics First  11:34 The Risks of Peptide Misuse 16:01 Should Doctors Prescribe Peptides? 17:54 When Optimism Becomes Self-Deception  26:45 The Myth of Billionaire-Funded Longevity 28:38 The Promise and Risk of Mitochondrial Drugs 31:49 Why Truth Matters in Longevity Science 35:28 Can We Cure All Diseases? 38:55 The Future of Personalized Longevity 42:38 How to Spot a Credible Longevity Clinic 48:02 Peptide Red Flags to Watch For 49:42 The Myth of Longevity Shortcuts 52:33 The Misinformation Problem in Longevity  58:12 The Most Effective Longevity Drug 01:02:37 If Tomorrow Was Your Last Day... Connect with Matt Instagram: https://www.instagram.com/mkaeberlein [https://www.instagram.com/mkaeberlein]  LinkedIn: https://www.linkedin.com/in/mkaeberlein [https://www.linkedin.com/in/mkaeberlein]  X: https://x.com/mkaeberlein [https://x.com/mkaeberlein]  Connect with Aubrey Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/ [https://www.linkedin.com/in/aubrey-de-grey-24260b/] Instagram: https://www.instagram.com/aubreydegrey/ [https://www.instagram.com/aubreydegrey/] X: https://x.com/aubreydegrey [https://x.com/aubreydegrey] Connect with Johannes Website: https://johannesweiss.at/ [https://johannesweiss.at/]  LinkedIn: https://at.linkedin.com/in/johannesweiss-longevity [https://at.linkedin.com/in/johannesweiss-longevity]  Connect with Brian Website: https://medicine.nus.edu.sg/sites/briankennedylab/ [https://medicine.nus.edu.sg/sites/briankennedylab/]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]

25. Juni 20261 h 3 min
Episode Longevity Experts: Why Nobody Treats Death Like the Emergency it is! Cover

Longevity Experts: Why Nobody Treats Death Like the Emergency it is!

Can AI help us defeat aging or are we still missing the pieces that matter most? In this episode, Adam and Nathan explore the growing intersection of AI and longevity. They discuss whether accelerating artificial intelligence could unlock breakthroughs in medicine, or if biology remains too complex for current models to solve. The conversation breaks down the major approaches to extending human lifespan, from cellular replacement and organ engineering to cryopreservation and partial reprogramming. They examine the promises, limitations, and biggest unanswered questions facing the field today. The episode also dives into the deeper motivations behind longevity research. From the fear of death and the loss of loved ones to the possibility of a future where aging is optional, Adam and Nathan share why they believe extending healthy human life may be one of humanity’s most important challenges. About the Guests Adam Gries is the founder and CEO of Vitalism, a nonprofit dedicated to accelerating progress in longevity and human life extension. He is also the creator of Vitalist Bay, a leading gathering that brings together scientists, entrepreneurs, and investors working to solve aging. Nathan Cheng is the co-founder and CEO of the Longevity Biotech Fellowship. He is a leading advocate for emerging longevity technologies, helping connect researchers, founders, and investors working to extend healthy human lifespan and accelerate progress in rejuvenation biotechnology. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why AI could accelerate longevity research * The most promising approaches to reversing aging * Where current AI tools fall short in biology * Which longevity breakthroughs may arrive first * The opportunities and risks facing the longevity movement * What a future without aging could look like ⏱ Timestamps 00:00 Intro 00:10 AI Could Change Everything 01:16 Most People Misunderstand Longevity 03:28 The Radical Plan to Replace Your Body 07:33 The AI-Longevity Convergence 14:05 Why AI Still Can’t Understand Biology 19:26 The Longevity Gold Rush 22:22 The Next Trillion-Dollar Drug 25:16 The Fear Every Longevity Expert Faces 30:37 The Biggest Myth in Longevity 33:03 When Could Aging Be Solved? 37:36 The Case for Optimism 39:57 The Disaster That Could Set Longevity Back Decades 44:29 A World Without Aging 50:35 What Happens If Death Becomes Optional? 53:11 The Role You Can Play 56:51 Your Race Against Time 01:02:15 If Tomorrow Is Your Last Day... Follow Adam: Website: https://vitalismfoundation.org/ [https://vitalismfoundation.org/]  LinkedIn: https://www.linkedin.com/in/adamgries [https://www.linkedin.com/in/adamgries]  X: https://x.com/adamgries [https://x.com/adamgries]  Follow Nathan: Website: https://nathancheng.xyz/ [https://nathancheng.xyz/]  Website: https://www.longbiofellowship.org/ [https://www.longbiofellowship.org/]  LinkedIn: https://ca.linkedin.com/in/nathan-cheng-6b464b207 [https://ca.linkedin.com/in/nathan-cheng-6b464b207]  X: https://x.com/realnathancheng [https://x.com/realnathancheng]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

12. Juni 20261 h 3 min
Episode Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet) Cover

Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet)

Joe Betts-LaCroix and Retro Biosciences recently raised funding at a $1.8 billion valuation. In his first podcast appearance since the announcement, Joe shares his vision for extending healthy human lifespan and the breakthroughs driving the longevity industry forward. Joe Betts-LaCroix explains why aging is becoming a legitimate scientific target. He shares how new discoveries are turning longevity from speculation into measurable biology. The conversation explores how AI is accelerating research, while highlighting why biology remains one of the hardest problems to solve. Even with smarter models, real-world testing and clinical trials still take time. Joe also discusses Alzheimer's, partial cellular reprogramming, and the future of longevity medicine. He shares why exercise remains the best longevity tool available today and what the next decade could look like for human health. Joe is the CEO of Retro Biosciences and a longtime entrepreneur focused on science and technology. His mission is to extend healthy human lifespan and accelerate breakthroughs in aging research. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why Sam Altman backed Retro Biosciences * The discovery that changed aging research forever * How AI is transforming biotech and longevity * Why curing all diseases in 10 years is unlikely * What Retro's Alzheimer's programs are targeting * Why biology is harder than most people realize * The longevity intervention Joe recommends today * How aging may become a treatable condition * What the longevity industry could look like by 2030 * Joe's vision for the future of human health and AI ⏱ Timestamps 00:00 Intro 00:16 AI's Role in Longevity 03:26 Will AI Cure All Diseases? 09:41 Why Biology Is So Hard to Solve 13:17 Building Technology That Matters 15:06 Adding 10 Healthy Years to Life 18:08 Inside Retro's Clinical Trial 19:31 The Different Types of Longevity Companies 22:10 Are We Already in the Singularity? 24:46 Why Investors Are Betting on AI Biotech 26:15 AI as the New Electricity 27:01 The Biggest Risks Facing Longevity 30:54 Why More Competition Is Good 32:44 Solving Alzheimer's Disease 34:26 Aging Biology and Future Therapeutics 38:25 The Biggest Aging Myth 39:41 The Most Underrated Voices in Longevity 40:25 The Best Longevity "Hack" 46:13 The Future of Longevity by 2030 50:49 If Tomorrow Was Your Last Day... Follow Joe: Website: https://www.retro.bio/ [https://www.retro.bio/]  LinkedIn: https://www.linkedin.com/in/bettslacroix [https://www.linkedin.com/in/bettslacroix]  X: https://x.com/bettslacroix [https://x.com/bettslacroix]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

5. Juni 202651 min