GSD Venture Studios Podcasts by Gary Fowler

From Signal to Cure: How AI is Ending the "Trial-and-Error" of Modern Medicine with Elaine Phan & Andreas Taylor

In this episode of the GSD Presents Silicon Valley AI & Tech series, we sit down with the visionary founders of Matrix Edge Therapeutics, Elaine Phan and Andreas Taylor. We dive deep into how they are building the "Signal → Cure → Longevity" AI infrastructure to revolutionize drug discovery and patient stratification. Learn how continuous patient signals and agentic AI are being used to reduce clinical trial-and-error, speed up cure development, and ultimately extend human healthspan. Key Topics Covered: The shift from reactive medicine to AI-driven Precision Medicine. How "Continuous Patient Signals" improve subtyping and stratification. The role of AI in streamlining the lifecycle from drug discovery to post-market management. The future of longevity and bio-tech innovation. About the Guests: Elaine Phan: Founder of Matrix Edge Therapeutics, Biopharma leader (20+ years), NIH AI strategist, and UC Berkeley/Stanford/Georgia Tech alumna. Andreas Taylor: Co-Founder & CTO, Genentech veteran, Data Scientist, and expert in agentic AI applications and drug delivery. Connect with GSD Venture Studios: gsdvs.com #PrecisionMedicine #AIinHealthcare #Longevity #DrugDiscovery #Biotech #GSDVS #TopGlobalStartups #HealthTech #BioPharma

The Death of SaaS and the Era of AGI: How Software Must Evolve to Survive with Patrick Murphy

Join Patrick Murphy, Co-Founder and CEO of Maket, for a high-stakes conversation on the future of the technology industry. With over one million users on his generative architecture platform, Patrick has a front-row seat to the radical shifts in how software is built and consumed. In this episode, we explore Patrick’s bold thesis on the "death of SaaS," where AI is heading in the next 24 months, and the specific strategies companies must use to AGI-proof their products before traditional software models become obsolete. 🎯 Insights You’ll Learn: ✓ The Death of SaaS: Why the traditional subscription model is facing an existential crisis ✓ AGI-Proofing: How to build defensible software in a world of autonomous intelligence ✓ Where AI is Headed: The transition from co-pilots to fully independent agents ✓ Generative Architecture: How Maket scaled to 1M users by rethinking the design process ✓ Moving beyond the interface: Why the next wave of winners will focus on outcomes, not tools ✓ Lessons from the frontlines: Balancing rapid AI growth with long-term business stability ✓ Why the democratization of design is just the beginning for generative technology 🌍 Why This Matters: The "SaaS gold rush" is over. As AI becomes capable of generating code, workflows, and designs on the fly, the value of a static software subscription is plummeting. Patrick Murphy argues that to survive, founders must stop building tools and start building "Original Intelligence" ecosystems that can withstand the arrival of AGI. This is a must-listen for any leader trying to understand the new rules of the software economy. 👤 Expert Background: • Co-Founder & CEO of Maket, a generative architecture platform with 1M+ users • Former U.S. Congressman and leader in innovation policy • Serial entrepreneur recognized for bridging the gap between tech and traditional industries • Expert in scaling consumer-facing AI products to global audiences • Strategist focused on the intersection of AGI, construction tech, and business longevity 🎙️ Hosted by Gary Fowler, CEO of GSD Venture Studios — global AI entrepreneur, investor, and innovation leader spotlighting founders navigating the realities of building in the AI era. 💡 Perfect For: SaaS founders, venture capitalists, software engineers, real estate tech leaders, and strategic planners looking to future-proof their companies against AGI disruption. 🚀 Timely Topic: As the barrier to entry for software creation hits zero, the next generation of winners will be those who master the "outcome-based" economy and build platforms that AGI cannot simply replicate. Subscribe for more global founder conversations from GSD Venture Studios: https://gsdvs.com #SaaS #AGI #GenerativeAI #FutureOfTech #StartupStrategy #MaketAI #SoftwareEngineering #PatrickMurphy #GaryFowler #GSDVentureStudios

Autonomous Dining: Redefining the Future of Quick-Service Restaurants with Nipun Sharma

Join Nipun Sharma, Co-Founder and CEO of Appetronix, for an exploration into the next frontier of hospitality: the fully autonomous restaurant. With over 17 years of leadership across global restaurant brands and a background in Wall Street investment banking, Nipun is uniquely positioned to bridge the gap between traditional food service and high-tech automation. In this episode, we discuss how Appetronix is using robotics and data science to deliver made-to-order meals without on-site staff, solving the industry’s most persistent labor and consistency challenges. 🎯 Insights You’ll Learn: ✓ The evolution from Wall Street to the world’s first autonomous robotic restaurants ✓ How machine learning ensures culinary excellence and consistency at scale ✓ Solving the labor crisis: Operating high-volume QSRs without on-site staff ✓ The intersection of food manufacturing and supply chain in a robotic ecosystem ✓ Lessons from managing 10+ restaurant brands across global markets ✓ The "Back-of-House" Revolution: Why robotics are the new standard for efficiency ✓ Strategic vision for the future of dining: Where technology meets hospitality 🌍 Why This Matters: The restaurant industry is facing a perfect storm of rising labor costs, high turnover, and thinning margins. Nipun Sharma is proving that the solution isn't just "better management," but a fundamental shift in business architecture. By integrating advanced robotics into the quick-service model, Appetronix is creating a scalable, resilient dining experience that meets the demands of the modern consumer while providing a sustainable path forward for operators. 👤 Expert Background: • Co-Founder and CEO of Appetronix, an autonomous robotic restaurant pioneer • Former Chief Operating Officer for global public restaurant chains • 17+ years of experience managing 10+ restaurant brands and food production facilities • Background in Investment Banking and Private Equity on Wall Street • Graduate of McGill University and a recognized leader in food-tech innovation 🎙️ Hosted by Gary Fowler, CEO of GSD Venture Studios — global AI entrepreneur, investor, and innovation leader spotlighting founders navigating the realities of building in the AI era. 💡 Perfect For: Restaurateurs, food-tech investors, robotics engineers, supply chain executives, and entrepreneurs interested in the automation of the service economy. 🚀 Timely Topic: As the food service industry moves toward a "tech-first" model, the next generation of winners will be those who can blend culinary art with robotic precision to create high-margin, consistent, and staff-less dining environments. Subscribe for more global founder conversations from GSD Venture Studios: https://gsdvs.com #FoodTech #RoboticRestaurants #Appetronix #RestaurantAutomation #QSR #FutureOfDining #MachineLearning #NipunSharma #GaryFowler #GSDVentureStudios

The Invisible Revolution: Why AI is the Next Frontier for Global Agriculture with Muzaffar Manghi

Join Muzaffar Manghi, Co-founder and Global Commercial Lead of Farmdar, for a compelling look at why the AI revolution seems to be happening everywhere except in the fields. With a unique background spanning two decades in global marketing leadership and a deep personal history in farming, Muzaffar is on a mission to bring "Space-Tech" to the soil. In this episode, we explore how AI is actually being used in agriculture today—not as a buzzword, but as a practical tool for crop insights, sustainability, and global food security. 🎯 Insights You’ll Learn: ✓ The Visibility Gap: Why the AI revolution is lagging in the agritech sector ✓ How Farmdar uses AI and space technology to generate actionable crop insights ✓ Real-world applications: How businesses are actually deploying AI on the farm ✓ Bridging the divide: Moving from legacy marketing at Ogilvy & Mather to agritech innovation ✓ The intersection of satellite data and ground-level farming intuition ✓ Why agriculture is the ultimate high-stakes environment for AI-driven decision-making ✓ Scaling a B2B agritech platform across global markets and diverse climates 🌍 Why This Matters: Agriculture is the backbone of the global economy, yet it remains one of the least digitized industries. As climate change and population growth put unprecedented pressure on our food systems, the ability to monitor and optimize every acre becomes a survival necessity. Muzaffar Manghi is proving that by combining the power of AI with space-based data, we can create a more resilient, predictable, and profitable future for farmers and the global supply chain. 👤 Expert Background: • Co-founder & Global Commercial Lead of Farmdar, an AI-powered B2B agritech platform • 22+ years of leadership experience at global agencies Ogilvy & Mather, Leo Burnett, and JWT • Deep-rooted background in family agriculture, providing a unique "insider" perspective • Specialist in space-tech applications for large-scale agricultural monitoring • Expert in B2B growth strategy and global brand scaling 🎙️ Hosted by Gary Fowler, CEO of GSD Venture Studios — global AI entrepreneur, investor, and innovation leader spotlighting founders navigating the realities of building in the AI era. 💡 Perfect For: Agritech founders, food supply chain executives, sustainability officers, AI researchers, and investors looking for the next untapped frontier in digital transformation. 🚀 Timely Topic: With global food demand rising, the next generation of winners will be those who can transform "invisible" farm data into visible, actionable insights that drive yield and reduce environmental impact. Subscribe for more global founder conversations from GSD Venture Studios: https://gsdvs.com #Agritech #AIinAgriculture #SpaceTech #Farmdar #GlobalFoodSecurity #SustainableFarming #B2BGrowth #MuzaffarManghi #GaryFowler #GSDVentureStudios

The Agentic Ecosystem of 2026: Navigating the Future of Autonomous AI with Deniz Soylular

Join Deniz Soylular, Co-founder and CPO of Mindra, for a forward-looking discussion on the next major evolution in technology: Agentic AI. As a pioneer in AI infrastructure, Deniz is building the multi-agent systems that allow AI to move from simple chatbots to autonomous workers. In this episode, we explore what the agentic ecosystem will look like over the next year, how established companies must adapt to keep pace, and what it takes to lead as a young entrepreneur in the fastest-moving tech landscape in history. 🎯 Insights You’ll Learn: ✓ The Agentic Shift: Moving from passive AI tools to autonomous multi-agent systems ✓ 2026 Roadmap: How the agentic ecosystem will evolve in the next 12 months ✓ Strategic Adaptation: How existing companies should react to the rise of AI agents ✓ Product Design for 2026: What defines a winning "Agent-First" product or idea ✓ The Founder’s Journey: Challenges and advantages of being a young tech entrepreneur ✓ Scaling Infrastructure: Insights from raising $1.2M in pre-seed for AI agents ✓ Bridging the Gap: Turning academic AI research into scalable, market-ready products 🌍 Why This Matters: We are entering an era where AI doesn't just answer questions—it executes workflows. This transition to agentic systems is fundamentally changing how software is built, sold, and used. For companies and founders, understanding the infrastructure behind these autonomous agents is no longer optional; it is the blueprint for staying relevant in 2026 and beyond. 👤 Expert Background: • Co-founder and CPO of Mindra, an AI infrastructure startup • Lead Developer of autonomous multi-agent systems with $1.2M in pre-seed funding • Computer Science professional with a background from Koç University • Innovation leader recognized for advancing scalable AI technologies • Expert in bridging the divide between AI research and commercial product development 🎙️ Hosted by Gary Fowler, CEO of GSD Venture Studios, global AI entrepreneur, investor, and innovation leader spotlighting founders navigating the realities of building in the AI era. 💡 Perfect For: AI researchers, startup founders, product managers, enterprise strategists, and young entrepreneurs looking to build in the agentic AI space. 🚀 Timely Topic: As 2026 becomes the year of the "Agentic Enterprise," the biggest opportunities lie not in the models themselves, but in the infrastructure that allows them to collaborate and solve complex problems autonomously. Subscribe for more global founder conversations from GSD Venture Studios: https://gsdvs.com #AgenticAI #Mindra #AIAgents #MultiAgentSystems #StartupGrowth #YoungEntrepreneurs #AIInfrastructure #DenizSoylular #GaryFowler #GSDVentureStudios