Chelation Therapy with Sergio A. Sobredo, MD, Bernardo Valero, ND, and Yanai Calderon, RN- ep 15 of the Iron DPC podcast
Stefan interviews Sergio A. Sobredo, MD, Bernardo Valero, ND, and Yanai Calderon, RN on Chelation Therapy.
Chelation therapy is a medical treatment that uses special agents—most commonly EDTA (ethylenediaminetetraacetic acid)—administered intravenously (IV) to bind ("chelate") to certain metals and minerals in the bloodstream. These bound complexes are then excreted through the urine via the kidneys. The term comes from the Greek word "chelos," meaning claw, reflecting how the chelating agent grabs onto targeted substances.FDA-Approved Use
* It is an established, FDA-approved treatment for heavy metal poisoning (e.g., lead, mercury, arsenic, or other toxic metals) and certain conditions like iron overload (hemochromatosis).
* In these cases, it effectively reduces dangerous metal buildup that can damage organs, the nervous system, kidneys, and more.
* Support cardiovascular health by potentially reducing arterial plaque, improving blood flow, decreasing inflammation, and lowering oxidative stress (some point to the removal of excess calcium or toxic metals that contribute to atherosclerosis).
* Help with symptoms linked to chronic metal exposure, such as fatigue, brain fog, neurological issues, or immune suppression.
* Burning or discomfort at the IV site
* Low blood pressure, headache, nausea, or fatigue
* Drops in essential minerals (e.g., calcium, zinc) → requires monitoring and supplementation
* Rare but serious issues like kidney strain or allergic reactions
* Evidence-based, medically supervised chelation for toxic metal removal and cardiovascular support.
* Services for patients (finding certified providers, consultations, lab coordination).
* Support for clinics/providers (training, protocols, implementation of chelation programs).
* Additional options like their Chel8® at-home oral/rectal chelation kit for accessibility.
Off-Label / Integrative UsesIn integrative and functional medicine circles, IV chelation is often used beyond heavy metal detoxification. Proponents suggest it may: Large studies (like the TACT trial) have explored its role in heart disease, with mixed results—some subgroups (e.g., people with diabetes or prior heart events) showed modest benefits, but mainstream organizations like the Mayo Clinic, Cleveland Clinic, and Harvard Health generally state that evidence for heart disease treatment remains limited or inconclusive, and it's not a standard or proven therapy for atherosclerosis, stroke prevention, or similar conditions.
Risks and Side EffectsWhen properly supervised, it's considered relatively safe for approved uses, but risks include: It's critical to use it under medical supervision with proper testing (e.g., heavy metal labs) — never with unregulated over-the-counter products.
What is ChelationDoctors.com?
ChelationDoctors.com is a nationwide network that connects patients with A.C.A.M.-certified practitioners (American College for Advancement in Medicine). ACAM is an organization focused on integrative medicine that offers specialized training and certification (CCT – Certified Chelation Therapy) for physicians administering chelation safely and effectively.
They position chelation as a tool to address heavy metal burden and related health issues, delivered by practitioners with ACAM's advanced chelation training.