Managing Patients With Neurotrophic Keratitis (NK)

Podcast de Annenberg Center for Health Sciences

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Tecnología y ciencia

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Acerca de Managing Patients With Neurotrophic Keratitis (NK)

The treatment of patients with NK, a rare disease of the eye that can lead to blindness, has evolved beyond treating symptoms to treatment that targets the root cause of the disease – nerve damage. Thus, early diagnosis is critical. Faculty discuss the etiology, diagnosis, staging, and treatment of patients with NK. In addition to an overview of symptomatic care and emerging treatments, the safety, efficacy, storage, and administration of cenegermin are explained in detail. Clinical and real-world questions are discussed, related to patient education, provided by multidisciplinary faculty.

Todos los episodios

4 episodios

Patient Education & Cases

* Principles * Case #1 * Case #2 Key Concepts: * Patient education about the disease and its natural history if left untreated is important * Interprofessional, multidisciplinary care is associated with the best patient outcomes

5 de jun de 2024 - 13 min

Treatment

* Team-based care * Treatment * General care * Prevention * Symptomatic treatment * Cenegermin * Safety, efficacy, role in treatment/patient selection * Cost * Storage and administration * Corneal neurotization * Investigational therapies Key Concepts: * Most patients should receive basic preventive and symptomatic care, as well as active treatment in certain cases * Cenegermin promotes corneal healing and is the only medication approved for the treatment of patients with neurotrophic keratitis

5 de jun de 2024 - 19 min

Screening & Diagnosis

* Clinical manifestations * Screening * Tools to test corneal sensitivity * Diagnostic algorithm * Disease staging * Considerations for referral Key Concepts: * Patients who are candidates for screening include those with a variety of genetic, system, central nervous system, or ocular diseases, such as diabetes mellitus, multiple sclerosis, and Alzheimer’s disease, or who us contact lenses or eyedrops with preservatives * Corneal sensitivity can be tested various ways and is critical to make the diagnosis * Cenegermin is self-administered and requires the patient be thoroughly educated regarding storage, handling, and administration

5 de jun de 2024 - 20 min

Overview

* Definition * Epidemiology * Natural history * Patient burden

5 de jun de 2024 - 6 min

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