Omslagafbeelding van de show The Y in Psychiatry

The Y in Psychiatry

Podcast door NguyenInDoubt

Engels

Technologie en Wetenschap

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Over The Y in Psychiatry

"The Y in Psychiatry" – a pragmatically endearing podcast talking to the med students, residents, fellows, and attendings of the medicine world about the nuances of psychiatry.Each episode are discussions exploring the intersections of the mental health, medicine, and the human experience.Together, we'll uncover the hidden "Y" – the compelling reasons, profound insights, and groundbreaking discoveries shaping the psychiatric landscape.So grab a seat, warm beverage, tune in, and let's embark on this journey to unlock the mysteries of the human psyche, only on "The Y in Psychiatry."Find articles on our episodes here:https://open.substack.com/pub/nguyenindoubt

Alle afleveringen

21 afleveringen

aflevering Cobenfy Unleashed: Psychiatry's New Frontier artwork

Cobenfy Unleashed: Psychiatry's New Frontier

Send us Fan Mail [https://www.buzzsprout.com/2185312/fan_mail/new] Cobenfy doesn't block dopamine — and that's the whole point. In this special episode, we step away from the bipolar just a bit to unpack the first genuinely new mechanism in schizophrenia treatment in decades. We break down how Cobenfy pairs xanomeline (a brain-penetrant M1/M4 muscarinic agonist) with trospium (a peripheral blocker that curbs the side effects), trace its surprising betel-nut origins, and explain the why behind the how: quieting dopamine in the striatum for positive symptoms and boosting GABA in the prefrontal cortex for cognition — all without the D2 blockade that brings EPS, weight gain, and sedation. https://www.nguyenindoubt.com/theyinpsych https://feeds.buzzsprout.com/2185312.rss

6 jun 2026 - 20 min
aflevering Late Life Depression: When the Golden Years Turn Grey (and the SSRIs Don't Shine) artwork

Late Life Depression: When the Golden Years Turn Grey (and the SSRIs Don't Shine)

Send us Fan Mail [https://www.buzzsprout.com/2185312/fan_mail/new] It never gets old to talk about late-life depression. Lets explore why growing older can sometimes mean growing sadder. We prance through executive dysfunction, vascular woes, inflammatory fires, and amyloid beta blues.  We’ll discuss why SSRIs might not be the golden ticket and what alternatives, like dopamine agonists, rTMS, and even ECT, can brighten those grey years. Plus, we'll ponder if your patient is depressed, or if their brain is just throwing a vascular tantrum. Tune in, turn up your hearing aids, and fluid restrict for the next 20 minutes if you have the worlds smallest bladder. https://www.nguyenindoubt.com/theyinpsych https://feeds.buzzsprout.com/2185312.rss

28 mrt 2025 - 18 min
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