The Wellness Roundtable

Wisdom at Midlife and Beyond with Chip Conley

Midlife isn’t a crisis—it’s a calling. In this episode, New York Times bestselling author and Modern Elder Academy founder Chip Conley sits down with host Alexia Brue to reframe aging as a powerful phase of reinvention. Drawing from his work with Airbnb and MEA, Chip explores how emotional resilience, community, and “life literacy” can become the true metrics of a long, meaningful life. With wit and wisdom, he challenges conventional career arcs and invites listeners to consider what a purposeful second (or third) act could look like. Beth McGroarty of the Global Wellness Institute also joins the conversation to share data on the demographic shifts driving this reframing of midlife. She unpacks how aging boomers are rejecting traditional retirement, how longevity is reshaping work itself, and why we need bold new models for connection, housing, and purpose in later life. Inside this Episode: * Why wisdom—not youth—may be the most undervalued longevity asset * Emotional, cognitive, and social well-being as pillars of healthspan * New rites of passage: why we need a midlife curriculum * The Modern Elder Academy and the future of multi-generational living * Beth McGroarty: Rise of “Don’t-Call-It-Senior-Living” concepts like Mather, the wellness industry’s opportunity to support older workers, and the economic imperative to reimagine purpose after 60 * Why longevity solutions must go beyond biology to meaning, contribution, and community Resources Mentioned: * Modern Elder Academy [https://www.modernelderacademy.com] * Global Wellness Institute [https://www.globalwellnessinstitute.org] * Mather Institute [https://www.matherinstitute.com] Hosted by: Alexia Brue, co-founder of Well+Good [http://www.wellandgood.com]; founder of a new healthspan training studio, The Practice [http://www.thepracticegreenwich.com]; member of the Global Wellness Institute [https://globalwellnessinstitute.org/] Board of Advisors To learn more about the Global Wellness Institute please visit us at global wellness institute.org [http://globalwellnessinstitute.org/], connect with us on Instagram [https://www.instagram.com/global_wellness_institute/] and subscribe to our YouTube [https://www.youtube.com/channel/UCCV2J3laUzGBFFTgnzQg8xQ] channel.  Produced by: Emily Roberts [https://www.instagram.com/emroberts.m] and Ali Alquiza [https://www.instagram.com/alialquiza] of Over Lunch  [https://www.overlunch.co/] Music provided by: Myndstream    [https://myndstream.com/]  Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com [https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.fountainlife.com%2f&c=E,1,L3t4-TQi5mQK-NFM2b_nL25jqOObpwuA7QnqA_MUjeWPwSn6qT1UxkxEaTbXFasY_6xI-NnAeqBq0NRXa572CKdOe8G6cWOhHAVenliHJPmIeITc&typo=1] to learn more. Subscribe, rate, & review wherever you listen to podcasts!

Why Skin is the Next Frontier in Longevity with Dr. Carolina Oliveira

What if your skincare routine could go beyond aesthetics and actually slow aging at the cellular level? In this episode of The Wellness Roundtable: Longevity, Alexia Brue sits down with Carolina Oliveira, MD / co-founder and CEO of OneSkin, a biotech company on a mission to transform skin from a cosmetic afterthought to a longevity biomarker. Dr. Oliveira shares how her team of scientists developed OS-01, the first topical peptide shown to reduce the burden of senescent cells in skin. We explore the clinical validation behind the product, why “skinspan” matters for your healthspan, and how your skin’s biological age may be a bellwether for systemic inflammation and immune health. This is not your average skincare chat—it’s a science-backed conversation about the future of personalized longevity, from barrier function to bioinformatics.  This episode also features insights from Beth McGroarty, VP of Research & Forecasting at the Global Wellness Institute.  Inside This Episode:  * Why skin is more than cosmetic: it’s a modifiable aging organ * The role of senescent cells in driving systemic inflammation * How OneSkin developed and validated its OS-01 peptide * The surprising link between topical products and internal biomarkers * What most longevity enthusiasts overlook about skin health * How OneSkin is earning credibility with leaders like David Sinclair and Peter Diamandis * Daily protocols: How Dr. Oliveira approaches her own longevity stack Resources & Mentioned: * OneSkin’s OS-01 peptide * Mentions: David Sinclair, Peter Diamandis, Bryan Johnson Hosted by: Alexia Brue, co-founder of Well+Good [http://www.wellandgood.com]; founder of a new healthspan training studio, The Practice [http://www.thepracticegreenwich.com]; member of the Global Wellness Institute [https://globalwellnessinstitute.org/] Board of Advisors To learn more about the Global Wellness Institute please visit us at global wellness institute.org [http://globalwellnessinstitute.org/], connect with us on Instagram [https://www.instagram.com/global_wellness_institute/] and subscribe to our YouTube [https://www.youtube.com/channel/UCCV2J3laUzGBFFTgnzQg8xQ] channel.  Produced by: Emily Roberts [https://www.instagram.com/emroberts.m] and Ali Alquiza [https://www.instagram.com/alialquiza] of Over Lunch [https://www.overlunch.co/] Music provided by: Myndstream    [https://myndstream.com/] Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com [https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.fountainlife.com%2f&c=E,1,L3t4-TQi5mQK-NFM2b_nL25jqOObpwuA7QnqA_MUjeWPwSn6qT1UxkxEaTbXFasY_6xI-NnAeqBq0NRXa572CKdOe8G6cWOhHAVenliHJPmIeITc&typo=1] to learn more. Subscribe, rate, & review wherever you listen to podcasts!

Why Women’s Health is Central to Longevity with Dr. Piraye Beim

Short Summary: Women may live longer—but they spend more of those years in poor health. In this essential conversation, Piraye Beim, MD & founder of Celmatix, reveals why ovarian aging is the hidden accelerant of female biological decline—and why extending ovarian healthspan could be the next major breakthrough in longevity science. From inflammaging to AMH biomarkers, Dr. Beim brings cutting-edge reproductive science into the center of the longevity discourse. This episode also features insights from Beth McGroarty, VP of Research & Forecasting at the Global Wellness Institute.   Inside this episode: * The “gonadal gap”: why menopause accelerates aging for women * Why ovarian function is a key regulator of brain, bone, and metabolic health * How tracking AMH levels could transform preventive care for women in their 30s and 40s * The underfunding of female longevity research—and how that’s starting to change * ARPA-H and other public-private partnerships funding therapeutic innovations * The potential to delay menopause and extend healthspan through new medical approaches Resources Mentioned: * Celmatix [https://www.celmatix.com] * ARPA-H research on ovarian aging * Global Wellness Institute [https://globalwellnessinstitute.org] Hosted by: Alexia Brue, co-founder of Well+Good [http://www.wellandgood.com]; founder of a new healthspan training studio, The Practice [http://www.thepracticegreenwich.com]; member of the Global Wellness Institute [https://globalwellnessinstitute.org/] Board of Advisors To learn more about the Global Wellness Institute please visit us at global wellness institute.org [http://globalwellnessinstitute.org/], connect with us on Instagram [https://www.instagram.com/global_wellness_institute/] and subscribe to our YouTube [https://www.youtube.com/channel/UCCV2J3laUzGBFFTgnzQg8xQ] channel.  Produced by: Emily Roberts [https://www.instagram.com/emroberts.m] and Ali Alquiza [https://www.instagram.com/alialquiza] of Over Lunch  [https://www.overlunch.co/] Music provided by: Myndstream    [https://myndstream.com/]  Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com [https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.fountainlife.com%2f&c=E,1,L3t4-TQi5mQK-NFM2b_nL25jqOObpwuA7QnqA_MUjeWPwSn6qT1UxkxEaTbXFasY_6xI-NnAeqBq0NRXa572CKdOe8G6cWOhHAVenliHJPmIeITc&typo=1] to learn more. Subscribe, rate, & review wherever you listen to podcasts!

Functional Medicine Is Longevity Medicine: Dr. Robin Berzin on Biomarkers, AI, and the Future of Healthspan

Short Summary:  What does a true longevity care model look like in practice—not just in theory? Alexia sits down with Robin Berzin, MD and founder and CEO of Parsley Health, the nation’s largest functional medicine and longevity clinic. A longtime force in personalized medicine, Dr. Berzin offers a rare window into how Parsley is merging diagnostics, clinical care, and innovation to shift the healthcare paradigm—from reactive to radically proactive. In this conversation, Dr. Berzin unpacks the most important—and overlooked—biomarkers for healthspan, the cultural moment that catapulted longevity into the mainstream, and why many people are chasing biohacks while ignoring the root causes of the diseases they already have. Inside this episode: * The six biomarker domains that matter most—and why conventional labs fall short * Why strength training and sauna are at the top of her own longevity list * The truth about peptides, GLP-1s, and whether rapamycin is ready for prime time * How Parsley is using AI to scale personalization—without losing the human touch * What women really need to know about hormone therapy, inflammation, and hidden thyroid issues * Why she believes estrogen may be “the new longevity drug” Whether you're a clinician, a consumer, or somewhere in between, this conversation offers a grounded, data-informed look at what it really takes to extend not just lifespan, but healthspan.  Resources Mentioned: * Parsley Health [https://www.parsleyhealth.com/] * Dr. Robin Berzin’s Newsletter [https://newsletter.robinberzinmd.com/] * Supplement tracking app: SuppCo [https://supp.co/] * Robin on Instagram: @robinberzinmd Hosted by: Alexia Brue, co-founder of Well+Good [http://www.wellandgood.com]; founder of a new healthspan training studio, The Practice [http://www.thepracticegreenwich.com]; member of the Global Wellness Institute [https://globalwellnessinstitute.org/] Board of Advisors To learn more about the Global Wellness Institute please visit us at global wellness institute.org [http://globalwellnessinstitute.org/], connect with us on Instagram [https://www.instagram.com/global_wellness_institute/] and subscribe to our YouTube [https://www.youtube.com/channel/UCCV2J3laUzGBFFTgnzQg8xQ] channel.  Produced by: Emily Roberts [https://www.instagram.com/emroberts.m] and Ali Alquiza [https://www.instagram.com/alialquiza] of Over Lunch  [https://www.overlunch.co/] Music provided by: Myndstream    [https://myndstream.com/]  Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com [https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.fountainlife.com%2f&c=E,1,L3t4-TQi5mQK-NFM2b_nL25jqOObpwuA7QnqA_MUjeWPwSn6qT1UxkxEaTbXFasY_6xI-NnAeqBq0NRXa572CKdOe8G6cWOhHAVenliHJPmIeITc&typo=1] to learn more. Subscribe, rate, & review wherever you listen to podcasts!

The Business of Aging Well with Abby Levy

Short Summary: Abby Levy, co-founder of Primetime Partners and a leading longevity investor, joins Alexia Brue to break down the massive opportunity—and responsibility—facing business leaders in the age of longevity. From redefining retirement to redesigning financial services and wellness products for older consumers, Abby shares a venture capitalist’s view on where this market is headed, and how brands must evolve to meet the needs of a longer-lived population.   This episode also features insights from David Stewart, founder of the innovative high-growth media platforms of Ageist and SuperAge, and a passionate champion of the modern 50+ lifestyle.   Inside this episode: * Why the “longevity economy” is one of the biggest demographic shifts of our time * Healthspan, wealthspan, and workspan: the new pillars of aging well * How retirement is being reframed as a 30+ year life phase * Investment trends in telemedicine, caregiving tech, and financial wellness * Bridging the gap between wellness culture and precision health solutions Resources Mentioned: * Primetime Partners [https://www.primetimepartners.com] * Ageist [https://www.ageist.com/] and Super Age [https://superage.com/] * Global Wellness Institute – Longevity Economy Reports [https://globalwellnessinstitute.org] Hosted by: Alexia Brue, co-founder of Well+Good [http://www.wellandgood.com]; founder of a new healthspan training studio, The Practice [http://www.thepracticegreenwich.com]; member of the Global Wellness Institute [https://globalwellnessinstitute.org/] Board of Advisors To learn more about the Global Wellness Institute please visit us at global wellness institute.org [http://globalwellnessinstitute.org/], connect with us on Instagram [https://www.instagram.com/global_wellness_institute/] and subscribe to our YouTube [https://www.youtube.com/channel/UCCV2J3laUzGBFFTgnzQg8xQ] channel.  Produced by: Emily Roberts [https://www.instagram.com/emroberts.m] and Ali Alquiza [https://www.instagram.com/alialquiza] of Over Lunch  [https://www.overlunch.co/] Music provided by: Myndstream    [https://myndstream.com/]  Thank you to our sponsor, Fountain Life, for supporting the GWI Podcast. Head to FountainLife.com [https://linkprotect.cudasvc.com/url?a=https%3a%2f%2fwww.fountainlife.com%2f&c=E,1,L3t4-TQi5mQK-NFM2b_nL25jqOObpwuA7QnqA_MUjeWPwSn6qT1UxkxEaTbXFasY_6xI-NnAeqBq0NRXa572CKdOe8G6cWOhHAVenliHJPmIeITc&typo=1] to learn more. Subscribe, rate, & review wherever you listen to podcasts!