Immunology Digest
Link to the study: https://pubmed.ncbi.nlm.nih.gov/26491068/
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4 Folgen
When the Immune System Turns on Bone Marrow: The Role of IFN-γ (Part II)
When the Immune System Turns on Bone Marrow: The Role of IFN-γ (Part I)
MDSCs in Cancer (Part II)
We continue to discuss a recent study that examines the role of Myeloid-derived Suppressor Cells in cancer and the expression of a receptor, DR-5, as a way to target these cells. Article: Condamine T, Kumar V, Ramachandran IR, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014;124(6):2626-2639. doi:10.1172/JCI74056 https://pubmed.ncbi.nlm.nih.gov/24789911/ [https://pubmed.ncbi.nlm.nih.gov/24789911/]
MDSCs in Cancer (Part I)
We discuss a recent study that examines the role of Myeloid-derived Suppressor Cells in cancer and the expression of a receptor, DR-5, as a way to target these cells. Article: Condamine T, Kumar V, Ramachandran IR, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014;124(6):2626-2639. doi:10.1172/JCI74056 https://pubmed.ncbi.nlm.nih.gov/24789911/ [https://pubmed.ncbi.nlm.nih.gov/24789911/]
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