Immunology Digest

When the Immune System Turns on Bone Marrow: The Role of IFN-γ (Part II)

Link to the study: https://pubmed.ncbi.nlm.nih.gov/26491068/

When the Immune System Turns on Bone Marrow: The Role of IFN-γ (Part I)

Link to the study: https://pubmed.ncbi.nlm.nih.gov/26491068/

MDSCs in Cancer (Part II)

We continue to discuss a recent study that examines the role of Myeloid-derived Suppressor Cells in cancer and the expression of a receptor, DR-5, as a way to target these cells. Article: Condamine T, Kumar V, Ramachandran IR, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014;124(6):2626-2639. doi:10.1172/JCI74056 ⁠https://pubmed.ncbi.nlm.nih.gov/24789911/ [https://pubmed.ncbi.nlm.nih.gov/24789911/]

MDSCs in Cancer (Part I)

We discuss a recent study that examines the role of Myeloid-derived Suppressor Cells in cancer and the expression of a receptor, DR-5, as a way to target these cells. Article: Condamine T, Kumar V, Ramachandran IR, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest. 2014;124(6):2626-2639. doi:10.1172/JCI74056 https://pubmed.ncbi.nlm.nih.gov/24789911/ [https://pubmed.ncbi.nlm.nih.gov/24789911/]