The Beyond Tomorrow Podcast with Julian Issa

LONGEVITY EXPERTS: How Close Are We to Solving Death?

What’s the biggest problem in longevity today: bad science, hype, or misplaced optimism? This episode is brought to you by NADclinic.com [http://nadclinic.com], the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ [https://nadairx.com/]  This debate brings together leading voices in longevity to separate evidence from speculation. They discuss why misinformation is growing and why many people chase advanced treatments before addressing basic health. The panel explores longevity escape velocity, healthspan versus lifespan, and how much progress has actually been made. They debate whether dramatic life extension is near or still much farther away than many believe. The conversation also examines peptides, NAD+ infusions, longevity clinics, and biological age tests. Along the way, they discuss risk, regulation, incentives, and how to distinguish credible medicine from marketing. Get to Know the Guests: Matt Kaeberlein is a biogerontologist and leading aging researcher known for his work on the biological mechanisms of aging and interventions that promote healthy longevity. Aubrey de Grey is a biomedical gerontologist and longevity advocate best known for developing strategies to repair age-related cellular damage and accelerate progress toward extending healthy human lifespan. Dr. Brian Kennedy is a renowned aging researcher and former director of the Centre for Healthy Longevity at the National University of Singapore, focused on translating longevity science into real-world health interventions. Johannes Weiss is the founder and CEO of Longevity Center Vienna, where he focuses on preventive medicine, root-cause health optimization, and personalized longevity strategies. He is an international speaker and practitioner known for combining longevity science, neurofeedback, and mitochondrial health to improve healthspan. What You’ll Learn * Why misinformation is growing in longevity * Healthspan vs. lifespan vs. longevity escape velocity * Why health basics matter more than longevity hacks * What the evidence says about peptides and NAD+ * How to spot credible longevity clinics * Why biological age tests remain controversial ⏱ Timestamps00:00 Intro 00:48 The Most Dangerous Force in Longevity 02:17 Why Longevity Isn't Medicine Yet 07:23 Why Clinical Trials Still Matter 08:15 The Hidden Bias in Longevity Data 09:40 Can You Make Money in Longevity? 10:34 Fix the Basics First  11:34 The Risks of Peptide Misuse 16:01 Should Doctors Prescribe Peptides? 17:54 When Optimism Becomes Self-Deception  26:45 The Myth of Billionaire-Funded Longevity 28:38 The Promise and Risk of Mitochondrial Drugs 31:49 Why Truth Matters in Longevity Science 35:28 Can We Cure All Diseases? 38:55 The Future of Personalized Longevity 42:38 How to Spot a Credible Longevity Clinic 48:02 Peptide Red Flags to Watch For 49:42 The Myth of Longevity Shortcuts 52:33 The Misinformation Problem in Longevity  58:12 The Most Effective Longevity Drug 01:02:37 If Tomorrow Was Your Last Day... Connect with Matt Instagram: https://www.instagram.com/mkaeberlein [https://www.instagram.com/mkaeberlein]  LinkedIn: https://www.linkedin.com/in/mkaeberlein [https://www.linkedin.com/in/mkaeberlein]  X: https://x.com/mkaeberlein [https://x.com/mkaeberlein]  Connect with Aubrey Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/ [https://www.linkedin.com/in/aubrey-de-grey-24260b/] Instagram: https://www.instagram.com/aubreydegrey/ [https://www.instagram.com/aubreydegrey/] X: https://x.com/aubreydegrey [https://x.com/aubreydegrey] Connect with Johannes Website: https://johannesweiss.at/ [https://johannesweiss.at/]  LinkedIn: https://at.linkedin.com/in/johannesweiss-longevity [https://at.linkedin.com/in/johannesweiss-longevity]  Connect with Brian Website: https://medicine.nus.edu.sg/sites/briankennedylab/ [https://medicine.nus.edu.sg/sites/briankennedylab/]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]

Longevity Experts: Why Nobody Treats Death Like the Emergency it is!

Can AI help us defeat aging or are we still missing the pieces that matter most? In this episode, Adam and Nathan explore the growing intersection of AI and longevity. They discuss whether accelerating artificial intelligence could unlock breakthroughs in medicine, or if biology remains too complex for current models to solve. The conversation breaks down the major approaches to extending human lifespan, from cellular replacement and organ engineering to cryopreservation and partial reprogramming. They examine the promises, limitations, and biggest unanswered questions facing the field today. The episode also dives into the deeper motivations behind longevity research. From the fear of death and the loss of loved ones to the possibility of a future where aging is optional, Adam and Nathan share why they believe extending healthy human life may be one of humanity’s most important challenges. About the Guests Adam Gries is the founder and CEO of Vitalism, a nonprofit dedicated to accelerating progress in longevity and human life extension. He is also the creator of Vitalist Bay, a leading gathering that brings together scientists, entrepreneurs, and investors working to solve aging. Nathan Cheng is the co-founder and CEO of the Longevity Biotech Fellowship. He is a leading advocate for emerging longevity technologies, helping connect researchers, founders, and investors working to extend healthy human lifespan and accelerate progress in rejuvenation biotechnology. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why AI could accelerate longevity research * The most promising approaches to reversing aging * Where current AI tools fall short in biology * Which longevity breakthroughs may arrive first * The opportunities and risks facing the longevity movement * What a future without aging could look like ⏱ Timestamps 00:00 Intro 00:10 AI Could Change Everything 01:16 Most People Misunderstand Longevity 03:28 The Radical Plan to Replace Your Body 07:33 The AI-Longevity Convergence 14:05 Why AI Still Can’t Understand Biology 19:26 The Longevity Gold Rush 22:22 The Next Trillion-Dollar Drug 25:16 The Fear Every Longevity Expert Faces 30:37 The Biggest Myth in Longevity 33:03 When Could Aging Be Solved? 37:36 The Case for Optimism 39:57 The Disaster That Could Set Longevity Back Decades 44:29 A World Without Aging 50:35 What Happens If Death Becomes Optional? 53:11 The Role You Can Play 56:51 Your Race Against Time 01:02:15 If Tomorrow Is Your Last Day... Follow Adam: Website: https://vitalismfoundation.org/ [https://vitalismfoundation.org/]  LinkedIn: https://www.linkedin.com/in/adamgries [https://www.linkedin.com/in/adamgries]  X: https://x.com/adamgries [https://x.com/adamgries]  Follow Nathan: Website: https://nathancheng.xyz/ [https://nathancheng.xyz/]  Website: https://www.longbiofellowship.org/ [https://www.longbiofellowship.org/]  LinkedIn: https://ca.linkedin.com/in/nathan-cheng-6b464b207 [https://ca.linkedin.com/in/nathan-cheng-6b464b207]  X: https://x.com/realnathancheng [https://x.com/realnathancheng]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Longevity Scientist: Aging Is A Disease. We Just Don’t Know How to Treat (yet)

Joe Betts-LaCroix and Retro Biosciences recently raised funding at a $1.8 billion valuation. In his first podcast appearance since the announcement, Joe shares his vision for extending healthy human lifespan and the breakthroughs driving the longevity industry forward. Joe Betts-LaCroix explains why aging is becoming a legitimate scientific target. He shares how new discoveries are turning longevity from speculation into measurable biology. The conversation explores how AI is accelerating research, while highlighting why biology remains one of the hardest problems to solve. Even with smarter models, real-world testing and clinical trials still take time. Joe also discusses Alzheimer's, partial cellular reprogramming, and the future of longevity medicine. He shares why exercise remains the best longevity tool available today and what the next decade could look like for human health. Joe is the CEO of Retro Biosciences and a longtime entrepreneur focused on science and technology. His mission is to extend healthy human lifespan and accelerate breakthroughs in aging research. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why Sam Altman backed Retro Biosciences * The discovery that changed aging research forever * How AI is transforming biotech and longevity * Why curing all diseases in 10 years is unlikely * What Retro's Alzheimer's programs are targeting * Why biology is harder than most people realize * The longevity intervention Joe recommends today * How aging may become a treatable condition * What the longevity industry could look like by 2030 * Joe's vision for the future of human health and AI ⏱ Timestamps 00:00 Intro 00:16 AI's Role in Longevity 03:26 Will AI Cure All Diseases? 09:41 Why Biology Is So Hard to Solve 13:17 Building Technology That Matters 15:06 Adding 10 Healthy Years to Life 18:08 Inside Retro's Clinical Trial 19:31 The Different Types of Longevity Companies 22:10 Are We Already in the Singularity? 24:46 Why Investors Are Betting on AI Biotech 26:15 AI as the New Electricity 27:01 The Biggest Risks Facing Longevity 30:54 Why More Competition Is Good 32:44 Solving Alzheimer's Disease 34:26 Aging Biology and Future Therapeutics 38:25 The Biggest Aging Myth 39:41 The Most Underrated Voices in Longevity 40:25 The Best Longevity "Hack" 46:13 The Future of Longevity by 2030 50:49 If Tomorrow Was Your Last Day... Follow Joe: Website: https://www.retro.bio/ [https://www.retro.bio/]  LinkedIn: https://www.linkedin.com/in/bettslacroix [https://www.linkedin.com/in/bettslacroix]  X: https://x.com/bettslacroix [https://x.com/bettslacroix]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Derya Unutmaz: Human Death is Actually a Solvable Engineering Problem

Could AI help humanity cure aging and dramatically extend human life? Artificial intelligence is rapidly transforming medicine and longevity research. Scientists now believe AI could dramatically accelerate drug discovery, personalized healthcare, and treatments for aging itself. In this episode, Derya Unutmaz explains why he believes humanity could reach “longevity escape velocity” within the next decade. He discusses digital twins, AI-powered drug discovery, superintelligence, and the future of human health. Derya also explores the risks of advanced AI, arguing that the greatest danger is not the technology itself, but how humans choose to use it. Derya Unutmaz is an immunologist and longevity researcher whose work focuses on aging, human immunology, and AI-driven biotechnology. His research explores how artificial intelligence could transform disease treatment, lifespan extension, and the future of human health. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why Derya believes aging could soon become reversible * How AI is speeding up drug discovery and healthcare * What digital twins could mean for personalized medicine * How AI-powered labs may transform scientific research * The biggest risks and opportunities of advanced AI * Why tools like AlphaFold are changing biology forever * How AI could help prevent disease and extend human lifespan ⏱ Timestamps 00:00 Intro 00:02 Can Humans Live Indefinitely? 02:09 How AI Could Accelerate Longevity 08:09 Why Biology Needs Dynamic Data 12:18 AI-Powered Labs and Robot Scientists 16:36 How AI is Empowering Ordinary People 20:51 Why Humans Not AI Are the Real Threat 25:40 The Possibility of Curing Every Disease 28:43 How AI is Revolutionizing Drug Discovery 35:04 The Biggest Risk Over the Next Decade 40:49 The Economic and Social Impact of AI 46:36 AI, Nuclear Weapons, and Existential Risk 52:53 Why Aging is Humanity’s Biggest Threat 55:06 Do You Fear Death? 56:55 Religion, God, and Human Purpose 58:45 Could AI Become Conscious? 01:00:08 What Happens if Humans Stop Aging? 01:05:29 Why Accelerating Science Matters 01:08:54 Why You Should Embrace AI 01:11:46 Can AI Help Cure Cancer? 01:14:23 The Best Advice for the Future 01:16:48 Never Lose Hope Follow Derya: Facebook: https://www.facebook.com/derya/about [https://www.facebook.com/derya/about]  Instagram: https://www.instagram.com/derya_unutmaz_md/ [https://www.instagram.com/derya_unutmaz_md/]  LinkedIn: https://www.linkedin.com/in/deryaunutmaz [https://www.linkedin.com/in/deryaunutmaz]  X: https://x.com/DeryaTR_ [https://x.com/DeryaTR_]  Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Cuba Expert: This Will START the US Attack on Cuba SOON!

Could Cuba become America’s next geopolitical flashpoint? Cuba remains one of the most politically charged issues in American foreign policy. More than 60 years after the Cuban Revolution, debates around sanctions, regime change, and military intervention are once again intensifying. In this episode, Mikael Wolfe explains why Cuba is fundamentally different from Venezuela and Iran, and why a U.S. intervention would be far more complicated than many assume. He discusses Donald Trump’s approach to Cuba, the influence of Marco Rubio and Cuban-American politics, and how decades of sanctions have shaped Cuba’s economic crisis. Mikael also explores Obama-era diplomacy, the growing influence of China and Russia in the region, and whether peaceful political reform in Cuba is still possible without foreign intervention or regime change. Throughout the conversation, he challenges common narratives surrounding democracy, sovereignty, and America’s long relationship with the island. Mikael Wolfe is a historian, author, and lecturer at the Department of History at Stanford University whose research focuses on modern Latin America, Cuba, environmental history, and U.S.-Cuba relations. His work examines how politics, ideology, and resource conflicts have shaped Cuban society and its relationship with global powers. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com [https://nadclinic.com]. What You’ll Learn * Why Cuba still matters strategically to the U.S. * How Cuba’s system differs from Venezuela’s * Why Florida politics heavily shape Cuba policy * Why a U.S. intervention could happen but fail * How sanctions deepened Cuba’s economic crisis * Why Obama’s Cuba policy briefly changed everything * Whether Cuba can reform without regime change ⏱ Timestamps 00:00 Intro 00:14 Trump’s Intentions for Cuba 02:25 Cuba vs. Iran vs. Venezuela 06:10 Why Cuba Still Matters to the US 10:34 The Politics Behind Regime Change 16:26 Can Cuba Be Compared to Taiwan? 20:23 Chances of a US Military Intervention 24:42 What Happens Over the Next Six Months? 25:46 Why Cuba Could Be the Next Target 28:48 What Happened to “America First”? 31:47 Rubio’s Influence on Cuba Policy 38:04 The Castro Legacy 40:47 Why an Intervention Could Fail 41:33 Cuba’s Deepening Economic Crisis 45:55 Is Cuba Really a National Security Threat? 49:13 What Happens if the US Intervenes? 51:19 Cuba, Iran, China & Russia 53:36 Will Cuba Ever Become Democratic? 57:34 Final Thoughts for the World Follow Mikael: Website: https://history.stanford.edu/people/mikael-wolfe [https://history.stanford.edu/people/mikael-wolfe]  LinkedIn: https://www.linkedin.com/in/mikael-wolfe-5789952aa [https://www.linkedin.com/in/mikael-wolfe-5789952aa]  Connect with Julian: Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ [https://www.instagram.com/thebeyondtomorrowpodcast/]   Instagram: https://www.instagram.com/juliankissa/ [https://www.instagram.com/juliankissa/]   LinkedIn: https://uk.linkedin.com/in/julian-issa [https://uk.linkedin.com/in/julian-issa]   Website: www.beyondtomorrowpodcast.com [http://www.beyondtomorrowpodcast.com]  Email: bookings@beyondtomorrowpodcast.com [bookings@beyondtomorrowpodcast.com]  Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.