Well Woman Podcast - What is DHEA
DHEA should be used more but is not, because it's not taught.
DHEA has massive effects on all ages and protects all the organs. It helps prevent the diseases of ageing as well as giving mental and physical resilience and quality of life.
I give details in my book - Well Woman
What is DHEA? It is short for dehydroepiandrosterone.
I call it the quality of life hormone because it is 10-20 times more abundant in the body than any other hormone including vitamin D, progesterone, oestrogen, and testosterone. DHEA has associated with it a lot of important factors which include less depression and better psychological profiles; Also, there is lower perceived stress at work.
So, how does this all happen? As people get older their DHEA declines but also what drains it more is stress and disease. DHEA specifically has many effects on helping to prevent heart disease We also know that DHEA stimulates bone formation and that is because it turns into progesterone, oestrogen and testosterone which further helps bone.
When it comes to women, it helps their sexual satisfaction, fertility because it improves the egg, and it also improves vaginal tissue function. It is particularly good in post-menopausal women who don’t want to have oestrogen. In fact I will often in older people, just use some DHEA and melatonin to help quality of life.
DHEA also helps to prevent, improve and reduce autoimmune diseases like rheumatoid arthritis. It also helps in allergy.
DHEA has a lot of work that it does in the brain DHEA reduces metabolic syndrome, diabetes and helps you lose weight. DHEA helps chronic kidney disease, reduces inflammation and oxidation, and reduces mortality.
DHEA needs to be prescribed carefully by an experienced doctor.
REFERENCES
1. DHEA Monograph. Alt Med Rev. Vol 6, Number 3, 2001
2. Krzysztof Rutkowski et al. Review Article. Dehydroepiandrosterone (DHEA): Hypes and Hopes Drugs (2014) 74:1195–1207
3. Fernand Labrie. Chapter 4 – DHEA, Important Source of Sex Steroids in Men and Even More in Women. Progress in Brain Research. Volume 182, 2010, Pages 97–148
4. Abdulmaged M. Traish et al. Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology. The Journal of Sexual Medicine. Volume 8, Issue 11, pages 2960–2982, November 2011
5. N. Pluchino, et al., Neurobiology of DHEA and effects on sexuality, mood and cognition, J. Steroid Biochem. Mol. Biol. (2014), http://dx.doi.org/10.1016/j.jsbmb.2014.04.012
6. Rebecca K Sripada et al. DHEA Enhances Emotion Regulation Neurocircuits and Modulates Memory for Emotional Stimuli. Neuropsychopharmacology (2013) 38, 1798–1807; doi:10.1038/npp.2013.79; published online 24 April 2013
7. Lennartsson A-K, Theorell T, Rockwood AL, Kushnir MM, Jonsdottir IH (2013) Perceived Stress at Work Is Associated with Lower Levels of DHEA-S. PLoS ONE 8(8): e72460. doi:10.1371/journal.pone.0072460
8. Jean-Pierre Savineau et al. Role of DHEA in cardiovascular diseases Biochemical Pharmacology 85 (2013) 718–726
9. Edward P. Weiss et al. Dehydroepiandrosterone ( DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans. Aging, May 2011, Vol3. No 5
10. Christiaan Lucas Meuwese and Juan Jesus Carrero REVIEW ARTICLE
11. Chronic Kidney Disease and HypothalamicePituitary Axis Dysfunction: The Chicken or the Egg? Archives of Medical Research 44 (2013) 591e600
12. Moise ́s E. Bauer et al. Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review. Biogerontology DOI 10.1007/s10522-012-9412-5
13. Nikolaos Samaras et al. A Review of Age-Related Dehydroepiandrosterone Decline and Its Association with Well-Known Geriatric Syndromes: Is Treatment Beneficial? REJUVENATION RESEARCH Volume 16, Number 4, 2013&nbs
