Delta: HealthTech Innovators

How OpenEvidence Became a $12 Billion AI Healthcare Giant | Full Breakdown

OpenEvidence just hit a $12 billion valuation — here's the full story of how it happened. Daniel Nadler sold his first company, Kensho, to S&P Global for $550 million. Then he turned his attention to one of the most broken systems in the world — medical information. Hosts Roupen Odabashian, MD and Osama Hyder break down the full story of OpenEvidence — the AI-powered clinical decision support platform now used by 40% of US physicians, handling 358,000 queries per day. We cover Daniel's origin story from Toronto to Harvard PhD, the Federal Reserve, and the founding of Kensho in 2013. We explore the $550M S&P acquisition, his parallel career as a published poet and MoMA PS1 board member, co-founder Zachary Ziegler's background, the Mayo Clinic partnership, domain-specific AI architecture, the USMLE 100% score debate, and the explosive growth that followed. The second half dives into the funding roadmap (Series A–D), product expansion into AI Scribe and DeepConsult, the direct-to-physician business model, monetization strategy, competitive analysis, network effects, and bear case risks. Whether you're a physician, a health tech founder, or an AI investor — this is the most in-depth breakdown of OpenEvidence you'll find anywhere. Subscribe for weekly deep dives: deltahealth.tech [http://deltahealth.tech] | Sponsored by PMWC 2026 — use code DELTAHEALTH at pmwcintl.com [http://pmwcintl.com] Timestamps: 00:00 - Hook: Who is Daniel Nadler & Why OpenEvidence Matters 01:46 - Welcome & Host Introductions 05:48 - Daniel Nadler's Origin Story 12:10 - Harvard PhD & The Federal Reserve 17:00 - Founding Kensho Technologies (2013) 22:00 - S&P Global Acquires Kensho for $550M 29:38 - Poetry & Art Career (MoMA PS1) 31:29 - The Information Crisis in Medicine 48:25 - The Founding of UpToDate 1:02:26 - ChatGPT Launches (November 2022) 1:15:00 - Zachary Ziegler's Background 1:21:00 - Self-Funding & Founding OpenEvidence 1:27:46 - The Mayo Clinic Partnership 1:34:46 - Technical Architecture: AI, RAG & Citations 1:46:00 - USMLE 100% Score & The Debate 1:53:30 - Growth: 358,000 Queries Per Day 2:08:00 - Funding Roadmap: Series A Through D 2:40:00 - Future of AI & The Physician Relationship 2:45:17 - Product Expansion: AI Scribe & DeepConsult 3:05:00 - Direct-to-Physician Approach 3:17:20 - Business Model & Monetization 3:32:15 - Competitive Analysis & Network Effects 3:47:00 - Bear Case & Risks Hosts: Roupen Odabashian: roupen@deltahealth.tech [roupen@deltahealth.tech] | linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142 [http://linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142] Osama Hyder: osama@deltahealth.tech [osama@deltahealth.tech] | linkedin.com/in/sam-hyder [http://linkedin.com/in/sam-hyder]

How Doximity Built a $9B Monopoly Doctors Actually Love | The Full Story

In this episode, we dive deep into the incredible story of Doximity—the "LinkedIn for Doctors" that captured 80% of US physicians and became one of healthcare's most under-the-radar success stories. Thank you for the sponser of today’s episode 🎟️ PMWC Conference – Use code DELTAHEALTH at pmwcintl.com [http://pmwcintl.com] for a discount! 🔑 What You'll Learn: * How founder Jeff Tangney went from Epocrates (the first medical app on iPhone, endorsed by Steve Jobs) to building Doximity * Why Doximity succeeded where competitors like Sermo and Osmosis failed * The brilliant business model that keeps physicians happy while generating billions * How COVID-19 transformed Doximity's telehealth tools from 1M calls/month to 1M calls/day * Strategic acquisitions: Curative (staffing), Amion (scheduling), and Pathway (AI clinical decision support) * The explosive launch of Doximity GPT and the AI scribe wars * The controversial Open Evidence lawsuit shaking up healthcare AI ⚠️ Disclaimer: This is not financial advice. Do your own due diligence. Doximity Links * 🌐 Website: doximity.com [http://doximity.com] * 📈 Investor Relations: investors.doximity.com [http://investors.doximity.com] * 💼 Doximity LinkedIn: linkedin.com/company/doximity [http://linkedin.com/company/doximity] * 📱 Doximity App (iOS): apps.apple.com/us/app/doximity/id393714498 [http://apps.apple.com/us/app/doximity/id393714498] * 🏥 Curative (Physician Staffing): curative.com [http://curative.com] * 🩺 Pathway Medical: pathway.md [http://pathway.md] Hosts * Roupen Odabashian LinkedIn: linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142/ [http://linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142/] * Email: roupen@deltahealth.tech [roupen@deltahealth.tech] * Sam Hyder LinkedIn: https://linkedin.com/in/sam-hyder [https://linkedin.com/in/sam-hyder] * Email: osama@duniya.health [sam@placeholder.com] 🎧 Subscribe for more deep dives into the playbooks of successful healthcare companies! #Doximity #HealthTech #DigitalHealth #Telemedicine #PhysicianNetwork #StartupStory #HealthcareAI #LinkedInForDoctors

The Doctor Will Text You Now: How Councel Health is Scaling the "Clinician Cockpit" with AI

Join us for an insightful conversation with Dr. Rishi Khakhkhar, Chief Medical Officer at Counsel Health, as we explore how this AI-enabled virtual care company is transforming the way patients access healthcare through chat-based, physician-supervised medical AI. In this episode, we dive deep into: - How Counsel Health combines medical AI with real physicians for safe, supervised care - The patient journey: from AI-powered intake to physician consultation - Asynchronous vs. synchronous care and what it means for busy patients - Emergency escalation protocols and patient safety in AI-enabled care - The "clinician cockpit" - AI tools built for physicians by physicians - The future of longitudinal patient-physician relationships in virtual care - Counsel Health's $35M Series A led by Andreessen Horowitz and Google Ventures Dr. Khakhkhar shares his journey from ER physician at Mount Sinai during COVID-19 to helping build the next generation of telemedicine, and why he believes AI will help physicians focus on what matters most - the human moments of care. Timestamps 00:00 – Introduction 01:28 – Dr. Khakhkhar's Background & How He Joined Counsel Health 04:48 – The Patient Journey: From AI Chat to Physician 09:00 – Longitudinal Care & the Patient-Doctor Relationship 12:00 – Asynchronous vs. Near-Synchronous Care 15:00 – Emergency Escalation & Patient Safety Protocols 19:00 – AI as a Team Member, Not a Replacement 22:00 – Dr. Khakhkhar's Journey: COVID-19 & Virtual Care 24:22 – Funding: $35M Series A from a16z & Google Ventures 27:00 – The Clinician Cockpit: AI Tools for Physicians 31:00 – Isolating the Human Moment in Medicine LinkedIn: https://www.linkedin.com/in/rishi-khakhkhar [https://www.linkedin.com/in/rishi-khakhkhar] About Counsel Health Founded by Dr. Muthu Alagappan (former CMO of Notable Health, Stanford MD), Counsel Health is an AI-enabled virtual care company on a mission to be the primary doctor for the next billion people on earth. Company Website: https://www.counselhealth.com [https://www.counselhealth.com] Company LinkedIn: https://www.linkedin.com/company/counselhealth [https://www.linkedin.com/company/counselhealth] Founder LinkedIn (Dr. Muthu Alagappan): https://www.linkedin.com/in/muthualagappan [https://www.linkedin.com/in/muthualagappan] Host: Dr. Roupen Odabashian, MD, FRCPC, FASCO Hematology-Oncology Physician | Healthcare Innovation Enthusiast Connect with Us: 🎙️ Podcast: Delta HealthTech Innovators 💼 Host LinkedIn: https://www.linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142 [https://www.linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142] 📧 Email: roupen@deltahealth.tech [roupen@deltahealth.tech] Listen on: 🍎 Apple Podcasts: https://podcasts.apple.com/us/podcast/delta-healthtech-innovators/id1703827145 [https://podcasts.apple.com/us/podcast/delta-healthtech-innovators/id1703827145] ▶️ YouTube: https://www.youtube.com/@RoubenOdabashianMD [https://www.youtube.com/@RoubenOdabashianMD] 🎧 Spotify: https://open.spotify.com/show/2vYC26pNkZVIhsqloNcCm9 [https://open.spotify.com/show/2vYC26pNkZVIhsqloNcCm9]

Preventing Dialysis Access Failure: How Auvi Labs is Building a Wearable Ultrasound Device

Preventing Dialysis Access Failure: How Auvi Labs is Building a Wearable Ultrasound Device | Rishab Veldur & Kevin Volkema In this episode, I sit down with Rishab Veldur (CEO) and Kevin Volkema (COO) from Auvi Labs to discuss how they're tackling a critical problem in dialysis care. 40% of dialysis patients experience fistula or graft failure within their first year—leading to endless hospitalizations and life-threatening situations. Auvi Labs is building "Beacon," a wearable ultrasound patch that patients can use for just 10 minutes a day to detect early signs of access failure. We dive deep into their journey from a university capstone project to launching clinical pilots, the challenges of building a healthcare startup, and their unique approach to networking and building clinical partnerships. Whether you're a healthcare founder, engineer, or just interested in medtech innovation, this episode is packed with actionable insights. Timestamps • 00:00 – Introduction • 01:00 – The Problem: Dialysis Access Failure • 03:15 – From Acoustic Device to Wearable Ultrasound • 10:06 – The 20-Patient Pilot Study • 11:52 – How to Find Clinical Pilots • 17:40 – Networking Playbook for Healthcare Founders • 21:01 – The Power of a Founder Newsletter • 23:45 – Business Model & Value-Based Care • 29:19 – Biggest Risks & Clinical Integration Challenges • 36:04 – Bottlenecks for Scaling Key Takeaways 1 Start with the problem, not the solution – They pivoted from an acoustic device to ultrasound after learning what patients and physicians actually needed 2 Healthcare is relationship-based – Cold outreach has low success; invest in building genuine connections over time 3 Skip the big conferences early on – Niche events and reaching out to researchers on Google Scholar yields better results 4 Use your student email – Everyone wants to help students 5 Send a newsletter – Share highs AND lows to bring people along on your journey 6 Value-based care is the path – Working with kidney contracting entities can bypass traditional CPT code reimbursement Guest Links • 🌐 Website: auvilabs.com [http://auvilabs.com] • 💼 Rishab Veldur (CEO) LinkedIn: https://www.linkedin.com/in/rishab-veldur/ [https://www.linkedin.com/in/rishab-veldur/] • 💼 Kevin Volkema (COO) LinkedIn: https://www.linkedin.com/in/kevinvolkema/ [https://www.linkedin.com/in/kevinvolkema/] Host • 💼 Roupen Odabashian LinkedIn: https://www.linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142/ [https://www.linkedin.com/in/roupen-odabashian-md-frcpc-fasco-183aaa142/] • 📧 Email: roupen@deltahealth.tech [roupen@deltahealth.tech] #healthcarestartup #medtech #dialysis #wearables #digitalhealth #medicaldevice #startup #healthcare #founders

Dr. Amit Phull - Building Physician-First AI Tools at Doximity

Join us for an incredible conversation with Dr. Amit Phull, Chief Physician Experience Officer at Doximity, as we explore how the largest professional medical network in the United States is revolutionizing healthcare with AI-powered tools built by physicians, for physicians. In this episode, we dive deep into: - How Doximity grew to serve over 80% of U.S. physicians - The development of HIPAA-compliant AI tools including Doximity GPT - The importance of clinician input in healthcare technology - Real-world impact: How AI is saving physicians hours and improving patient care - The acquisition of Pathway (Montreal-based company) and integration of clinical decision support - Privacy-focused AI scribe technology generating millions of notes - Lessons learned from product failures and successes Dr. Phull shares his unique journey from computer engineering to emergency medicine, and how maintaining both clinical practice and tech expertise positions him to bridge the gap between technology and healthcare delivery. Timestamps [00:00:00] Introduction & Welcome [00:01:24] Dr. Phull's Journey: Computer Engineer to Emergency Physician [00:04:00] Role as Chief Physician Experience Officer [00:06:41] Why Maintaining Clinical Practice Matters [00:11:04] Introduction to Doximity Tools & Platform [00:14:52] The Secret Sauce: Clinician-Driven Development [00:18:44] Doximity GPT Evolution & HIPAA Compliance [00:22:21] Acquiring Pathway AI (Montreal) [00:28:41] AI Scribe: Privacy-First Documentation [00:30:52] Lessons from Product Failures [00:36:18] Success Story: 10% to 90% Prior Auth Approval Rate About Our Guest Dr. Amit Phull, MD Chief Physician Experience Officer, Doximity Board-Certified Emergency Medicine Physician Adjunct Lecturer, Northwestern University Feinberg School of Medicine Dr. Phull combines deep expertise in medicine, technology, and strategy. He completed his MD at University of Virginia (where he also earned a BS in Computer Science), finished emergency medicine residency at Northwestern, and has been with Doximity since 2014. He continues to practice emergency medicine while leading physician experience strategy for the nation's largest medical professional network. LinkedIn: https://www.linkedin.com/in/amit-phull-09931667/ [https://www.linkedin.com/in/amit-phull-09931667/] Doximity Website: https://www.doximity.com [https://www.doximity.com] Doximity LinkedIn: https://www.linkedin.com/company/doximity [https://www.linkedin.com/company/doximity] My email: roupen@deltahealth.tech [roupen@deltahealth.tech] YouTube: https://youtu.be/ElB-a5Mubm4 [https://youtu.be/ElB-a5Mubm4]