GLP-1 Side Effects Week by Week: What My First 7 Weeks Have Actually Felt Like
GLP-1 Side Effects Week by Week: What My First 7 Weeks Have Actually Felt Like
What actually happens in your body when you start a GLP-1 medication like Ozempic, Wegovy, Zepbound, or Mounjaro?
In this episode of the LoveThySelfies Podcast, I’m sharing the honest, behind-the-scenes story of my first seven weeks on a GLP-1 medication (Tirzepatide) —including the physical adjustments, emotional moments, and surprising things I wish someone had explained before I started.
Before beginning this journey, I searched the internet like everyone else. What I found were either miracle transformation stories or terrifying side-effect warnings. What I didn’t find were calm, detailed explanations of what the adjustment period actually looks like week by week.
So that’s what this episode is.
We’re talking about the real experience of starting a GLP-1 medication—from giving myself the first injection (and being terrified to do it), to navigating hydration, digestion, metabolism changes, workout adjustments, and the emotional side of changing my relationship with food.
Along the way, I’ll also explain the science happening inside the body, including how GLP-1 hormones influence appetite signaling, insulin sensitivity, digestion, dopamine pathways, hydration needs, and energy levels.
If you’re considering starting a GLP-1 medication, already taking one, or simply curious about how these medications work in the body, this episode will give you a grounded, compassionate overview of what the early weeks can look like.
In This Episode We Talk About
• What the first GLP-1 injection actually feels like
• Why appetite and food noise change in the brain
• The connection between GLP-1 and dopamine pathways
• Why fatigue can happen in early weeks
• How hydration and electrolytes impact energy levels
• What happens to digestion and gastric emptying
• Why some people experience constipation on GLP-1
• The difference between incline walking vs weighted walks
• How to support metabolism without stressing your body
• Why the weight-loss phase of GLP-1 treatment is just a season
The Telehealth Platform I Use for My GLP-1 Support:
If you’ve been following my journey and wondering where I get my GLP-1 support, I personally use WeightCare. It’s the telehealth platform I’ve been using during this season, and if you want to explore your own options through their medical team, you can use my code MELISSA22858 to save $200 on eligible programs.
Check out WeightCare here: https://www.joinweightcare.com/MELISSA22858 [https://www.joinweightcare.com/MELISSA22858]
*I may earn a small commission at no extra cost to you if you choose to use my link. This is not medical advice, and you should always talk with your healthcare provider about what’s right for your body.
Affiliate Resources Mentioned
These are products I personally use to support hydration, digestion, and recovery during this season.
Electrolytes, magnesium, fiber support, and hydration tools can make a huge difference during the early weeks of GLP-1 treatment.
If you choose to purchase through the links below, I may earn a small commission at no additional cost to you.
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This episode reflects my personal experience and research while working with my healthcare provider. It is not medical advice. Always consult your doctor before starting or changing medications, supplements, nutrition plans, or exercise routines.