Dhru Purohit Show

This episode is brought to you by BiOptimizers [https://bioptimizers.com/dhru], Cozy Earth [http://cozyearth.com/dhru], and Fatty15 [https://fatty15.com/DHRU]. When we think about treating depression, we rarely consider exercise. Yet emerging research shows it can be a powerful tool for managing mild to moderate depression, and it works well alongside other therapies—including medication. Today’s guest shares the science behind exercise and explores why more practitioners aren’t incorporating it into treatment conversations. Today on The Dhru Purohit Show, Dhru sits down with Dr. Nicholas Fabiano to explore the powerful role of exercise in treating depression. Dr. Fabiano introduces the FITT protocol for prescribing exercise and sheds light on the disconnect between physicians and patients when it comes to exercise recommendations. Dhru and Dr. Fabiano also discuss how research funding can shape treatment perspectives, the benefits of combining medication with lifestyle interventions, and the emerging role of creatine in brain energy and its potential impact on depression. Dr. Fabiano emphasizes why exercise is essential for mental health and advocates for a holistic approach to treating depression—one that includes lifestyle pillars like diet and sleep. Nicholas Fabiano is a psychiatry resident and researcher at the University of Ottawa. Drawing from his personal background in weightlifting and competitive soccer, Nicholas developed a strong interest in the use of exercise as a treatment for mental disorders, particularly depression. His research focuses on the intersection of mental and physical health, with a special emphasis on lifestyle psychiatry—exploring how exercise, diet, and sleep influence mental well-being. In this episode, Dhru and Dr. Fabiano dive into: * Exercise can be as effective as therapy in treating depression (00:27) * The importance of finding a provider who exercises and understands its benefits (01:57) * The impact of exercise on both the brain and body (04:53) * The misperception that all patients want quick fixes (11:11) * The side effects of medication and how lifestyle interventions can help counter them (19:18) * The FITT protocol and how to prescribe it effectively (23:56) * Reframing exercise as an intervention that empowers patients (31:54) * Heart rate variability, and why doing what you enjoy matters (31:42) * The benefits of stacking exercise with creatine (38:33) * How to incorporate creatine into your diet (44:24) * Exercise recommendations for beginners, family, and friends (45:02) * A lifestyle protocol that can actually induce depression (49:33) * Advocating for and educating the public on foundational principles (59:06) * An entrepreneurial approach to solving the mental health crisis (01:03:21) * How Dr. Fabiano became passionate about brain health (01:05:59) * His advice for beginners and how to follow his work (01:11:27) Also mentioned in this episode: * John Abramson's book - Sickening [https://a.co/d/gJ22UNS] * Try This: Three Super Crazy Facts about Big Pharma [https://dhrupurohit.com/try-this-three-super-crazy-facts-about-big-pharma/] * Study on BPA in pregnant women  [https://www.nature.com/articles/s41467-024-48897-8] For more on Dr. Fabiano, follow him on Instagram [https://www.instagram.com/doctorfabiano/], X/Twitter [https://twitter.com/NTFabiano], LinkedIn [https://ca.linkedin.com/in/ntfabiano], and his Website [https://www.researchgate.net/profile/Nicholas-Fabiano]. This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15. Go to bioptimizers.com/dhru [https://bioptimizers.com/dhru] now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase.  Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru [http://cozyearth.com/dhru] and use code DHRUP. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru [https://fatty15.com/DHRU?utm_source=podcast&utm_medium=2024&utm_campaign=podcast] and use code DHRU to replenish your C15 levels for long-term health. Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

This episode is brought to you by Pique Life [http://piquelife.com/dhru], Momentous [https://www.livemomentous.com/], and Lumebox [https://thelumebox.com/dhru].  When we think about disease and chronic illness, we don’t usually consider the possibility of a lab leak or a government experiment gone wrong. Today’s guest sheds light on her investigation into Lyme disease, its disturbing origins, and how it’s impacted patient treatment.  Today on The Dhru Purohit Show, Dhru sits down with writer and producer Kris Newby to discuss her theory on the origins of Lyme disease. She explores the possible role of weaponized ticks, the mismanagement of Lyme disease treatment, and the implications of military secrecy surrounding biological experiments. Kris also emphasizes the need for a deeper understanding of Lyme disease’s complexity and its broader impact on public health. She highlights the importance of awareness, research, and advocacy for better treatment options while sharing her personal journey with Lyme disease and how it affected her family. Kris Newby is an award-winning science writer and the senior producer of the Lyme disease documentary UNDER OUR SKIN, which premiered at the Tribeca Film Festival and was a 2010 Oscar semifinalist. Her book, BITTEN, won three international book awards for journalism and narrative nonfiction. Previously, she worked as a science and technology writer for Stanford Medical School, Apple, and other Silicon Valley companies. She is currently working on her second book. In this episode, Dhru and Kris dive into: * The sinister origins of Lyme disease (00:10) * What’s known so far and piecing together the facts (2:30) * The discovery of Lyme, its impact on public health, and the role of Big Pharma (10:30) * Theories of lab leaks and tick weaponization (17:00) * Military secrecy and cover-up tactics (23:00) * A congressman’s journey to investigate the origin of Lyme (28:00) * Optimism for future research and treatment (30:00) * Navigating tick-borne illness (32:30) * Historical context of biological warfare (35:00) * Connections between modern disease and bioengineering (36:20) * The role of ethics and accountability (39:20) * Kris’s personal journey with Lyme disease (41:20) Also mentioned in this episode: * Kris’ book Bitten [https://a.co/d/c2281tj] * Lyme Disease Resources [https://www.lymedisease.org/] * IGeneX Lab  [https://igenex.com/] * Galaxy Labs [https://www.galaxydx.com/] For more on Kris, follow her on Instagram [https://www.instagram.com/bittenthebook/], Facebook [https://www.facebook.com/bittenhistory/?modal=admin_todo_tour], X/Twitter [https://twitter.com/krisnewby], LinkedIn [https://www.linkedin.com/in/kris-newby-7315153/], and her Website [https://www.krisnewby.com/]. This episode is brought to you by Pique Life, Momentous, and Lumebox.  Right now, Pique Life is offering 20% off the Radiant Skin Duo plus a free beaker and frother when you go to piquelife.com/dhru [http://piquelife.com/dhru]. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com [https://www.livemomentous.com/] and enter promo code DHRU to get 20% off any order. Lumebox is offering my community $260 off their FDA-registered portable Red Light device!  That's over 40% off! Go to thelumebox.com/dhru [https://thelumebox.com/pages/dhru] and get your Red Light device.  Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

This episode is brought to you by BiOptimizers [https://bioptimizers.com/dhru], Our Place [http://fromourplace.com], and Manukora Honey [https://manukora.com/dhru]. Mental health disorders are on the rise in our modern world, as our brains and bodies face constant disruption from environmental toxins in the air, water, and food. Meanwhile, connection and stress look vastly different than they once did. Today’s guest sheds light on what has changed, why these disorders are increasing, and—most importantly—how to protect ourselves. Today on The Dhru Purohit Show, Dhru sits down with Dr. Drew Ramsey to discuss the current state of mental health and treatment. Dr. Ramsey breaks down the top lies we've been told about brain health and healing. He also explores the challenges of modern life, how they disrupt our brains and mental well-being, and the lifestyle habits that make these disruptions worse. Plus, he shares the optimal diet for reducing the risk of depression and neurodegenerative diseases, along with the powerful impact of journaling, spending time in nature, and building community. Drew Ramsey, MD, is a board-certified integrative psychiatrist, best-selling author, and a leading proponent of Nutritional Psychiatry and Mental Fitness. He served as an Assistant Clinical Professor of Psychiatry at Columbia University’s Vagelos College of Physicians and Surgeons for twenty years. Dr. Ramsey founded the Brain Food Clinic in New York City and Spruce Mental Health in Jackson, WY. A sought-after speaker, he conducts workshops nationwide, and his work has been widely featured in the media. In this episode, Dhru and Dr. Ramsey dive into: * Top misconceptions about healing the brain (1:14) * The biggest challenges impacting brain health today (4:12) * How to protect your brain from microplastics (8:10) * The top lifestyle habits damaging mental health (13:08) * Which diets increase the risk of depression and neurodegenerative diseases (18:18) * Is the chemical imbalance theory a myth, and the role of inflammation (26:42) * How to improve access to better medications (35:12) * The link between nutrition, depression, and finding the right practitioner (39:44) * How journaling and nature impact mental health (43:09) * Caring for elderly parents and the importance of community (47:57) * The role of psychedelics in mental health treatment (51:44) * How politics influence healthcare in America (1:17:40) * How to connect with Dr. Ramsey (1:24:35) Also mentioned in this episode: * Healing the Modern Brain [https://a.co/d/gI7r9Gi] * How to prescribe physical activity for depression [https://econtent.hogrefe.com/doi/10.1024/2674-0052/a000099] For more on Dr. Ramsey, follow him on Instagram [https://www.instagram.com/drewramseymd/], Facebook [https://www.facebook.com/drdrewramsey/], X/Twitter [https://twitter.com/DrewRamseyMD], and his Website [https://drewramseymd.com/]. This episode is brought to you by BiOptimizers, Our Place, and Manukora Honey. Go to bioptimizers.com/dhru [https://bioptimizers.com/dhru] now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase.  Reduce your toxic load by upgrading your cookware! Go to fromourplace.com [http://fromourplace.com] today and use promo code DHRU at checkout to receive 10% off any order. Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru [http://manukora.com/dhru] to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

This episode is brought to you by Levels [http://levels.link/dhru], Bon Charge [http://boncharge.com/DHRU], and Ollie [http://ollie.com], For years, many have believed that cancer is primarily genetic or just bad luck, but emerging research suggests we have far more control over our risk than previously thought. Dr. Thomas Seyfried's groundbreaking work reframes cancer as a metabolic dysfunction, focusing on its root cause rather than just treating symptoms. While controversial, this approach offers new hope for both practitioners and patients seeking alternative strategies for prevention and treatment. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with Dr. Thomas Seyfried and experts from the Hippocrates Research Foundation, a nonprofit dedicated to continuing Dr. Seyfried’s work by educating cancer patients on metabolic-based treatment approaches. Dr. Seyfried explores the role of oxidative stress, mitochondrial health, and glucose in cancer development and progression, along with his research on ketogenic diets as a promising solution to correct these imbalances. Den Stacey shares his journey of seeking guidance from the Hippocrates Research Foundation—ultimately becoming cancer-free. The Hippocrates Research Foundation team—Daniel Orrego, Dr. Gregory Howard, and Dr. Michelle Howard—discuss their research and their approach to guiding cancer patients by implementing a protocol designed to starve cancer while fueling the body. Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. With over 150 peer-reviewed publications, his research focuses on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases, as well as the role of calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and serves on the editorial boards of Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro. In this episode, Dhru and his guests dive into: * The role of mitochondrial dysfunction in cancer (04:05) * The promise of the ketogenic diet and its impact on cells (09:58) * How the ketogenic diet cuts off cancer’s fuel sources (20:37) * Den Stacey’s email about his experience with Dr. Seyfried’s protocol (26:54) * The Press-Pulse protocol used in Den’s treatment (30:25) * The role of stress reduction as a key part of the protocol (35:31) * The benefits of hyperbaric oxygen therapy (38:53) * Why pharmaceutical drugs and diet should be used in concert (40:47) * What an ideal cancer treatment team looks like (46:31) * Testing and evaluating the protocol in real-world cases (56:39) * Recognizing the success of the case study and the next steps (59:42) * Final thoughts (01:02:01) Also mentioned: * Full episode with Dr. Thomas Seyfried [https://podcasts.apple.com/us/podcast/a-radical-and-controversial-approach-to-starving/id1381257272?i=1000610846021&at=1l3vpUI&app=itunes&ct=LFV_3e074d624fc4eac7a193dc7fed7d8e4a&itscg=30440&itsct=catchall_p4&lId=28762810&cId=none&sr=4&src=Linkfire&ls=1] * Full episode with Den Stacey [https://podcasts.apple.com/us/podcast/a-step-by-step-break-down-of-dr-thomas/id1381257272?i=1000647378204] This episode is brought to you by Levels, Bon Charge, and Ollie, Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU [http://levels.link/DHRU]. Make moves on your metabolic health with Levels today.  Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU [http://boncharge.com/DHRU]and use coupon code DHRU to save 15%. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com [http://ollie.com], use the code DHRU and you’ll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]

This episode is brought to you by LMNT [http://drinklmnt.com/dhru], Maui Nui [http://mauinuivenison.com/DHRU], and Birch Living [https://birchliving.com/dhru].  When we think of stress, we often associate it with something negative—something to avoid. Our modern culture has fostered an environment of persistent chronic stress, yet at the same time, we've also eliminated beneficial stress by designing a life of chronic ease. Today's guest joins us to explain why stress isn't just unavoidable—it’s essential for growth. Today on The Dhru Purohit Show, Dhru sits down with Jeff Krasno, CEO and co-founder of Commune, to explore the benefits of positive stress in our modern world. Jeff explains why chronic stress harms our health and longevity, while adaptive stress—like fasting and hot/cold exposure—has been key to human evolution and survival. He also shares how to evaluate your protocols, behaviors, and routines to ensure they keep you in balance. Jeff is the co-founder and CEO of Commune, a masterclass platform focused on personal and societal well-being, and the co-creator of Wanderlust, a global series of wellness events. He also hosts the Commune podcast. His latest venture, Good Stress: The Benefits of Doing Hard Things, expands on his personal story and wellness protocols. Drawing from over 400 podcast conversations and his own experiences, the book explores deliberate, self-imposed behaviors that enhance social, psychological, and physical well-being.  In this episode, Dhru and Jeff dive into: * How chronic ease is leading to disease (00:37) * How to befriend stress (5:44) * Jeff’s personal journey and the health challenges that shaped him (09:50) * Fasting, hunger, and stress—how they can benefit you (23:34) * Fasting recommendations for women and the importance of an individualized approach (26:50) * Jeff’s Substack insights on weight loss (32:42) * Research on cold plunges, blood glucose, cancer, glutamate, immunotherapy, and more (36:50) * The future of health, chronic disease, systemic issues, and the decline of public trust in health and food institutions (43:19) * The impact of health podcasts, their practices, and how people are paying attention to new information (56:24) * How to lean into stressful conversations—plus tips for tackling them (59:18) * Evaluating our protocols, behaviors, and routines—do they help us find balance and return to center (1:19:50) * Final thoughts (1:24:45) Also mentioned in this episode: * Jeff’s new book - Good Stress: The Health Benefits of Doing Hard Things [https://a.co/d/48AWFsz] * Commune Podcast  [https://bit.ly/Communepodcast] * Gabor Mate - Kiyumi retreat [https://ww2.kiyumi.org/gabor-mate/] * Thomas Seyfried's glutamate research [https://www.nature.com/articles/s42003-019-0455-x] * KetoPet Sanctuary [https://ketopet.org/] For more on Jeff, follow him on Facebook [https://www.facebook.com/wecommune/], Instagram [https://www.instagram.com/onecommune/], X/Twitter [https://twitter.com/onecommune], Pinterest [https://www.pinterest.com/onecommune/], YouTube [https://www.youtube.com/onecommune], and his Website [https://www.onecommune.com/]. This episode is brought to you by LMNT, Maui Nui, and Birch Living. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru [http://drinklmnt.com/dhru] today. Right now Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru [http://mauinuivenison.com/dhru] to secure your access now —but hurry, supply is limited! To get 20% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru [https://birchliving.com/dhru] today. Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]