The Research Room

RESTART-PD: Augmented Reality for Parkinson’s Rehabilitation

How can cutting-edge augmented reality glasses transform traditional physiotherapy into engaging games for people living with Parkinson’s disease? In this episode, Lucy and Janine are joined by Chief Investigator Professor Rory O'Connor from the University of Leeds and Barri Morgan Jones from Strolll to explore the RESTART-PD project. This innovative research initiative focuses on an essential clinical and digital health priority: improving movement, balance, and daily function for individuals living with Parkinson's disease. Listen as we discuss the journey of utilising augmented reality headsets to turn standard, often repetitive rehabilitation exercises into fun, patient-centred games that can be played right at home. We discover the personal inspiration behind the Strolll technology behind this randomised controlled trial, and how remote clinical monitoring through a web portal dashboard can help support rehabilitation and tackle extensive NHS waiting lists.   Find out more about the RESTART-PD Trial: https://www.york.ac.uk/health-sciences/research/trials/ytutrialsandstudies/trials/restartpd/ Find out more about Strolll: https://www.strolll.co/ [https://www.strolll.co/]   Music by Matthew Bailey

Blood Cancer: Haematological Malignancy Research Network

How can a massive, real-world database tracking nearly 60,000 patients revolutionise our understanding of blood cancer treatment and patient care? In this episode, Lucy and Janine are joined by Professor Alex Smith and Professor Debra Howell from the University of York’s Epidemiology & Cancer Statistics Group to explore the Haematological Malignancy Research Network (HMRN). This major research initiative focuses on a critical health priority: collecting granular, population-based data to transform the care pathways for those diagnosed with blood cancers. Listen as we discuss the journey of building a 20-year registry that captures the detailed care pathway for over 100 different subtypes of blood cancer. We discover the powerful methodology behind combining large-scale epidemiology with qualitative patient interviews—revealing how real-world survival rates have doubled for certain conditions, the emotional anxieties of the "watch and wait" approach, and what the future holds for cutting-edge treatments like CAR T-cell therapy. PLUS, we find out what happens when "symbiotic nerds" unite to put the patient's lived experience at the absolute centre of data science!   HMRN website: https://hmrn.org/ [https://hmrn.org/] HMRN Publications: https://hmrn.org/publications/papers [https://hmrn.org/publications/papers] Music by Matthew Bailey

Gentle Years Yoga: Can Chair-Based Yoga Improve Quality of Life in Older Adults?

How can an adapted, chair-based yoga program improve the quality of life for older adults living with multiple long-term health conditions?    In this episode Lucy and guest host Emma are joined by Dr Laura Wiley from the University of York and Dr Lesley Ward from Northumbria University to explore the Gentle Years Yoga project. This major research initiative focused on a critical health priority: improving the quality of life for older adults living with multiple health conditions.   Listen as we discuss the journey of utilising a chair-based yoga programme developed by the British Wheel of Yoga to make the practice accessible outside of typical high-street studios. We discover the methodology behind this  randomised controlled trial as well as the qualitative data whic revealed the transformative impact that yoga can have. PLUS we get to hear the results!   Find out more about the Gentle Years Yoga Trial: https://www.google.com/search?q=https%3A%2F%2Fwww.york.ac.uk%2Fhealthsciences%2Fresearch%2Ftrials%2Fresearch%2Ftrials%2Fgentle-years-yoga%2F&authuser=2https://www.york.ac.uk/health-sciences/research/trials/ytutrialsandstudies/archive/gyy-trial/ Results paper 1: https://pubmed.ncbi.nlm.nih.gov/39259017/ Results paper 2: https://openresearch.nihr.ac.uk/articles/3-52/v2 Proces evaluation paper: https://pubmed.ncbi.nlm.nih.gov/40098115/   Music by Matthew Bailey

Pivoting in a Pandemic: Delivering Remote Support for Socially Isolated Older Adults

Did you know that persistent loneliness is as damaging to your physical health as smoking 15 cigarettes a day? For the final episode of our mental health mini-series, we’re joined by Dr Liz Littlewood and Professor Simon Gilbody from the University of York to explore the BASIL project. This massive research initiative stepped up during a global crisis to tackle a critical but overlooked issue: the mental health, depression, and rising isolation of older adults. Listen as we discuss the incredible journey of adapting brief psychological support into a fully remote, "telephone-first" intervention. We dive into how behavioural activation helps people reconnect with what brings value to their lives, stripping away "psychobabble" to keep things straightforward and co-produced alongside experts and users. They also share the historic scale of the BASIL+ trial, the largest ever randomised controlled trial of its kind, and how its positive results are shaping the future of NHS care by moving from treatment to prevention. Tune in to find out how a brief series of 30-minute phone calls managed to create a sustained reduction in depression 12 months down the line, and stick around for the end to hear a joke from the TV show Friends!   Find out more about BASIL: https://www.google.com/search?q=https://www.york.ac.uk/healthsciences/research/mental-health/projects/basil/https://sites.google.com/nihr.ac.uk/basil/ [https://sites.google.com/nihr.ac.uk/basil/] Read the results paper:  https://www.sciencedirect.com/science/article/pii/S2666756823002386 [https://www.sciencedirect.com/science/article/pii/S2666756823002386]   Music by Matthew Bailey

Co-Production in Custody: Creating a Mental Health Toolkit for Older Prisoners

How can digging into the past protect the future of mental health for older people in custody? For the next episode in our mental health mini-series, we’re joined by Professor Amanda Perry and Professor John Schofield to explore the PAMHOP project. This pioneering feasibility study is tackling a critical but overlooked issue: the mental and physical wellbeing of older people in custody by introducing co-produced, interactive workshops directly in prison sites. Listen as we discuss the massive gap in current research including a systematic review that did not find a single randomized controlled trial for this demographic. We dive into how the team designed and delivered custom interactive sessions, from archaeology activities to craft sessions and book clubs, with the goal of improving overall wellbeing. They also share how these insights are being used to develop a dedicated toolkit, providing prisons with a concrete framework to support mental and physical health of older people in custody.  Tune in to find out what happened when a workshop unexpectedly turned into a group song, and see how collaborating with the Prison Radio Association is amplifying the voices and restoring the confidence of people in custody!   Find out more about PAMHOP: https://www.york.ac.uk/healthsciences/research/mental-health/projects/physical-mental-health-older-prisoners/ [https://www.york.ac.uk/healthsciences/research/mental-health/projects/physical-mental-health-older-prisoners/]   Music by Matthew Bailey