#1: Endometrial Lining and Receptivity
Thin endometrial lining—when is it truly the barrier to implantation, and when is it just a number we’ve over-feared? Join Dr. GG Collins and Dr. Rachel Weinerman on the MRSI Talks Art Podcast as they unpack the science, the myths, and the practical strategies to optimize receptivity and get your patients truly transfer-ready.
CME CREDIT:
To learn more about the CME credit available, read the Accreditation Overview document [https://mrsimeeting.org/wp-content/uploads/2026/02/February-10_MRSi-Podcast-Series-2026_Accreditation-Overview-1.pdf], listen to the podcast and than complete the Credit Evaluation form [https://cine-med.com/certificate.php?id=900]. Visit https://mrsimeeting.org/podcast [https://mrsimeeting.org/podcast] to access the CME links.
For more information or to contact the MRSi team, visit: https://mrsimeeting.org/ [https://mrsimeeting.org/]. A special ‘thank you’ to Ferring Pharmaceuticals and their educational grant support for this activity.
HOSTED BY:
Angie Beltsos, MD: Executive Chair, Midwest Reproductive Symposium international
GUESTS:
Rachel Weinerman, MD: Senior Attending Physician, Division of Reproductive Endocrinology and Infertility University Hospitals Cleveland Medical Center Program Director, REI Fellowship, University Hospitals Fertility Center Associate Professor, Case Western Reserve University School of Medicine
GG Collins, MD: Medical Director and REI Physician, Wisconsin Fertility Institute
REFERENCES:
1. Legro RS, Zhang H; Eunice Kennedy Shriver NICHD Reproductive Medicine Network. Letrozole or clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med. 2014 Oct 9;371(15):1463-4. doi: 10.1056/NEJMc1409550. PMID: 25295506.
2. Quaas AM, Gavrizi SZ, Peck JD, Diamond MP, Legro RS, Robinson RD, Casson P, Christman GM, Zhang H, Hansen KR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network. Endometrial thickness after ovarian stimulation with gonadotropin, clomiphene, or letrozole for unexplained infertility, and association with treatment outcomes. Fertil Steril. 2021 Jan;115(1):213-220. doi: 10.1016/j.fertnstert.2020.07.030. Epub 2020 Sep 21. PMID: 32972733; PMCID: PMC7796980.
3. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER; Cooperative Multicenter Reproductive Medicine Network. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med. 2007 Feb 8;356(6):551-66. doi: 10.1056/NEJMoa063971. PMID: 17287476.
4. Schmiech K, Li M, Chen LX, Dow MP, Baker VL. Association of endometrial thickness with live birth rate: a study using the Society for Assisted Reproductive Technology Clinic Outcome Reporting System. Fertil Steril. 2025 Jul;124(1):79-87. doi: 10.1016/j.fertnstert.2024.12.032. Epub 2025 Jan 3. PMID: 39755137.
5. Gingold JA, Wu H, Lieman H, Singh M, Jindal S. Increasing endometrial thickness up to 12 mm is associated with increased odds of live birth among fresh and frozen-thawed autologous transfers with or without preimplantation genetic testing. Fertil Steril. 2025 Sep;124(3):478-486. doi: 10.1016/j.fertnstert.2025.04.032. Epub 2025 Apr 28. PMID: 40306566.
6. Genovese H, Mayo CA, Kalafat E, Fatemi H, Ata B, Garcia-Velasco J, Seli E. Does endometrial thickness impact live birth rate following a frozen embryo transfer: outcomes of 30 676 euploid single embryo transfers. Hum Reprod. 2025 Oct 1;40(10):1919-1927. doi: 10.1093/humrep/deaf129. PMID: 40639807.
7. Santamaria X, Liu JH, Aghajanova L, Isaacson K, Movilla P, Fernandez H, Capmas P, Donnez J, Simón C. Should we consider alternative therapies to operative hysteroscopy for the treatment of Asherman syndrome? Fertil Steril. 2020 Mar;113(3):511-521. doi: 10.1016/j.fertnstert.2020.01.022. Epub 2020 Feb 25. PMID: 32111470.
