The Optispan Podcast with Matt Kaeberlein

Longevity Problem: 70% Of All Deaths Are Caused By Aging - Dr. Andrew Steele

Longevity scientist Dr. Andrew Steele sits down with Dr. Matt Kaeberlein to make the provocative case that aging should be treated as humanity's greatest challenge, even bigger than climate change. In this deep conversation, they explore why two-thirds of all deaths are caused by aging, the cutting-edge science that's already extending healthy lifespan in animals, and what it would really mean to add decades of vitality to human life. From CRISPR gene therapies to senescent cell clearance, from the ethics of radical life extension to practical steps you can take today, this is an unflinching look at whether we can (and should) slow down aging itself.Timestamps00:00 [https://www.youtube.com/watch?v=-nPyorL4pRg] – Why Aging Is the Biggest Problem We’re Not Solving01:33 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=93s] – Is Aging Actually Fixable? What the Science Shows04:01 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=241s] – Overpopulation Myths vs. Longevity Reality09:02 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=542s] – Can We Slow Aging? What’s Working Now14:39 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=879s] – Inside the Longevity Divide: Hope vs. Hype18:45 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=1125s] – Healthspan vs. Lifespan: What Really Matters29:12 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=1752s] – Chronic Disease and the True Cost of Aging36:21 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=2181s] – The Most Promising Longevity Therapies Today56:56 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=3416s] – Biological Age Tests: What You Can Actually Trust01:53:17 [https://www.youtube.com/watch?v=-nPyorL4pRg&t=6797s] – The Future of Longevity: AI, Innovation, and What’s NextConnect with Dr. Andrew SteeleWebsite: https://andrewsteele.co.uk/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbUl0bzBYTDNqV2RCU3UxZGxnN3Y2MnUtd1JVZ3xBQ3Jtc0tsVHdsYUcwVVR1RHJybVhvSXdnN2RlOFh5cWd3cXBWdkxLa3paMktvbERscXhpMW14Q0l6bk1kYjdGRWdIVE83clNGSDJ5clRaSy1xWVA4Z2w3ZmhLYlFQeFB5d2laTWNzSlR4ZWNHWHJPeGhwRW9ndw&q=https%3A%2F%2Fandrewsteele.co.uk%2F&v=-nPyorL4pRg]YouTube:    / drandrewsteele   [https://www.youtube.com/DrAndrewSteele]Instagram:   / andrewjsteele   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbDJzb1NYZDkxVEljNHpucWRVd24weE55ZWkxd3xBQ3Jtc0ttdDVQZE10X20taml5RFRvTzJNMzRtRXU4NTdtMVM2WEdIQVN6ZGlVUTJ3RFMzS2h3U3A1dnJYd2ZBTTNUemZlaTR2M0JsZXFVZW9OSG5zM0xPSnZWMUxuT3FVdE5jM2dpU0VoS3BzM2xvWEJlWDdiUQ&q=https%3A%2F%2Fwww.instagram.com%2Fandrewjsteele&v=-nPyorL4pRg]Twitter:   / statto   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbDdXTzZXZE5jZ0Y3N3RtQ1NVbDFOWUJ1aGpzUXxBQ3Jtc0trSG5jSGxnaGZlOU1YdGM3QXNNa3c3czhsTU16bnhVNE0tMF9pVC01QTFjOWZEcHNwQVN4dXBueWVNdUUtY2MyR2ZoREJzR293YlBOVG1oUzJyWFlzLV8yeWVOWkZjRXZ3N0VEN1RTcWJzMzE1Qm1idw&q=https%3A%2F%2Ftwitter.com%2Fstatto&v=-nPyorL4pRg]LinkedIn:   / andrewsteele   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbGRlZWdEanltcjFrcmJoaWdJNHZTRkVRMnhmd3xBQ3Jtc0trd2Y3ZHNLYmpMZVp2cGxZaUlSS3hiU216SldzV3pNN1dWZDB1cHhPd0ttZGJpRDBheFVfV1NaQ0dUdjR0UHNCZnBnQmdMc1hsbVJVWXFHeTNVSTN1eG5LMWtiZVk5VXh0c2NGcVl1N1R5SkdFNHNRTQ&q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Fandrewsteele&v=-nPyorL4pRg]Bluesky: https://bsky.app/profile/statto.bsky.... [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHhvbXhmbUlWNnFtbWx6Nm1NVjlyNTVGWEJRd3xBQ3Jtc0tuOENwU2t4ZmxLVVlydzFZTXhwZ24tOVhXUFkxVHc1aGc4NTJ4RmFzOFRvQ21pY1FWakpFNlpYU0FJS0lRZWx3aGdWYXBCYUdMWVVaWUdPcHYza0tCdkVZUzBEZ2ppbFNYTEItX3ZZUWhYZlF6YlRERQ&q=https%3A%2F%2Fbsky.app%2Fprofile%2Fstatto.bsky.social&v=-nPyorL4pRg]Mastodon: https://mas.to/@statto [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbU1IV2xBUHBpOTZzOENmVW8tRXVseXNkdnk0Z3xBQ3Jtc0tsaFp3a19qbUc0UnBCZmFoTGp3YngzVGxveWxJUlc0TDdxcEtxc2dkZUNxbUkxbk5mR21Fa2VFUUtOTUVDLU1RQm52NUFkX0daSjJkUjVzMi1ST3J6R1VsRVI1ekpoXzlKaUhHQ2M5cmNoZFJPSHc3WQ&q=https%3A%2F%2Fmas.to%2F%40statto&v=-nPyorL4pRg]This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here:https://onebillionmedia.com/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqazRrelNBUWNURUdrWjNTVHc4a1BJeER4eFBEd3xBQ3Jtc0tsOG9WeVlkUXQ1UWVOTmJreV9iSkZfQTZid2pTcTNyT1diMGlNMkhWM0k5RWM0MGcycjJELWk2c0VxRTVTV0RqTTFjUk91UFpuVmFJQ0c2TW9YaVFFcEJUdERGUlBja2xFazl1a2dsRDZKRVNDR3U0VQ&q=https%3A%2F%2Fonebillionmedia.com%2F&v=-nPyorL4pRg]DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://x.com/Optispan_Inc [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbTdqQzF6U1owMHpURVpfUVlHR3FwUG4yZnNmd3xBQ3Jtc0trc3pEZGRqYzdjMTJXZWRxUmdGNjNtNWRmdEV3RkFjV3FubnI5Q2RqN18xV2k1YjM5S2h1VlJnSHF0NXZJMFQxMDIxdnVXOXo4eW9QZzRvbXBibUVfT2NXTGxHMVgzWjIxVzBQOVUxQ1ljS2Q2bDVlNA&q=https%3A%2F%2Fx.com%2FOptispan_Inc&v=-nPyorL4pRg]Twitter:   / mkaeberlein   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa1JnUHN0Q2tMeDBnWkFMYjRnelpkOEpoZG9vQXxBQ3Jtc0tuX0ZNVGZ3MG96anFpTk83TFp6NTZCYVFHZmdRYV9GSmhabnhhNXhKVVFzQ0pnTE9ZVjhRb3MwSjBxY3NaQ1QxMDhRY3pTNUxTc21HcVpRZXllenJDaGtyR2Q0djItSS1jMWdTdGs5aE82b3RmWnFDRQ&q=https%3A%2F%2Ftwitter.com%2Fmkaeberlein&v=-nPyorL4pRg]Linkedin:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbEFUcm56MzExM0hsTjB5NTNBOUVIZG5IbnlLUXxBQ3Jtc0trWmExTXkxT204OXZtSFhZaFQxSWhSQml1NklId0FSYW02SVUwVENUMG1UZGd5Q3JPVExJTDZnTW1UamNrRzNkaDdMcjl2N09yUmljMUgxVUpFTDljOFBwRW9wZGFwMlQydUNtUUpuUnJ6NzhPWmtfOA&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Foptispan&v=-nPyorL4pRg]Instagram:   / optispan_   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa3ZFSk5ERDdQelFHRXgtTGtFOUVHT3F4azhEUXxBQ3Jtc0tucDM5M2w3Rkk3Uy1DVktJYzB3T091dm1GVnJtZmJJZzRJbnNYT05vYU04NTkzUzd1dE9uamJxZTZCMElqbmZSZWQzYy1xSnZjVWpBMGhzUU9nRmVyNzJxWTdJRnFoMHZzQUlJdUxLMldoWGxGaU9yMA&q=https%3A%2F%2Fwww.instagram.com%2Foptispan_%2F&v=-nPyorL4pRg]TikTok:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa1NnNGlTcFdGUFRyS3RBOTRhWjJHU2M3UXp4Z3xBQ3Jtc0trTGpiQlk0VVhrUWdmMXhvUHFwUEpDeUlYYzEzc2RnUlhVOS13TU9JR05TdnBJclZ0ZHFzanIwV0U2WGFMN3lZTWt2RW9NYURheG1WWjcyUTloc2c1dm02OHBncjJmNmhHdnM5YTZjcXc4cXgtblY0OA&q=https%3A%2F%2Fwww.tiktok.com%2F%40optispan&v=-nPyorL4pRg]https://www.optispan.life/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbWl5OG80amRBTGJiT1dRQzBMN0hxQkt4d1p2UXxBQ3Jtc0tuRFZSUWNsZFJWZkxwYUZ6MFNNNU5UUWdFZFl3ZVBET0M0WE12ZmI3MnJEWXNPaFU5ZUR5ajZOUFdRdmhySFlGU01kUXIxTnJZdVF3OTEyRFpRWUttSkZzVTJ1SlFxcUhfYXhqVnZuaGJqOFlwR1JpUQ&q=https%3A%2F%2Fwww.optispan.life%2F&v=-nPyorL4pRg]

Scientist Reacts: Why Megadosing Creatine Is A Waste Of Time

Creatine is being called a "cognitive super-drug" that feels like "speed without the speed." Influencers are telling you to mega-dose 20 grams a day for brain power, bone health, and more. But what does the science actually say?In this episode, we go beyond the hype and fact-check the wildest creatine claims taking over the internet. I break down the real evidence on mega-dosing, and put the cognitive benefits to the testI react to clips from Paul Saladino, Jeff Cavalier, Rhonda Patrick, and Dave Asprey to separate proven fact from marketing fiction. Discover the simple, science-backed creatine protocol that actually works, and save your money (and your gut) in the process.This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here:https://onebillionmedia.com/00:01:23 - High-Level Reality Check on Creatine00:03:12 - Hosts' Personal Histories with Creatine00:05:17 - How to Evaluate Health Influencers & Their Claims00:08:40 - Paul Saladino (MD): Analysis of Mega-Dosing Claims (20g/day) for Brain & Bones00:23:16 - Jeff Cavaliere (Physical Therapist): Claims on Depression, Parkinson's, and MS00:31:22 - Discussion on Creatine for Sleep Deprivation & High Stress00:34:28 - The "No Downside" Myth & Side Effects (GI Issues, Microbiome)00:37:29 - Rhonda Patrick (PhD): "Feels Like Speed" Claim & Brain Aging00:46:00 - Dave Asprey: "Most Powerful Cognitive Drug" Claim00:53:02 - How Creatine Actually Works (The "Backup Battery" Analogy)00:53:49 - Final Take-Home Messages & Summary00:56:00 - Q&A: Best Time to Take Creatine & What to Do If You Miss a Day00:57:42 - Final Thoughts on Influencer HypeDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://x.com/Optispan_IncTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispan_/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/

We'll Pay $101 Million If You Prove You Can Reverse Aging

Subscribe to our channel:    / @optispan   [https://www.youtube.com/channel/UCSna7385c3Xg_4Too92NKMw]Get Our Newsletter (It's Free): https://www.optispan.life/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbENURWVqQkhGVkRFQ1YzeTViWDZVY3BoYWUtZ3xBQ3Jtc0tuTlR4Z21qU3JlMmE3WC1kZTJyLWJ5M2FsMFhPYkVSTDh5OTM4LU1GYTFXYkdwVTZBNk1tdU1yMTJtQ1A3WHphNjMwakhWZHBELTJLQVRES210MDVuZGlLWVlLalZjWE9QLWpjR1RRNGRERDVOclNhaw&q=https%3A%2F%2Fwww.optispan.life%2F&v=1JediNaSMf4]Join me for a fascinating conversation with Dr. Jamie Justice, Executive Director of the $101 Million XPRIZE Healthspan. In this podcast, we discuss the world of longevity science, from the ambitious goals of this global competition to the lessons learned from the stalled TAME trial.Dr. Justice explains how the XPRIZE is structured to find real-world solutions to extend human healthspan.Chapters: 00:01:31 [https://www.youtube.com/watch?v=1JediNaSMf4&t=91s] - Jamie's Role & The Mission of XPRIZE Healthspan00:02:29 [https://www.youtube.com/watch?v=1JediNaSMf4&t=149s] - What is the XPRIZE Foundation?00:05:36 [https://www.youtube.com/watch?v=1JediNaSMf4&t=336s] - The Genesis of the Healthspan Prize00:09:39 [https://www.youtube.com/watch?v=1JediNaSMf4&t=579s] - Why Commercial Success Matters for the Prize00:10:51 [https://www.youtube.com/watch?v=1JediNaSMf4&t=651s] - How to Win: The Competition Structure & Timeline00:18:50 [https://www.youtube.com/watch?v=1JediNaSMf4&t=1130s] - The 3 Key Healthspan Pillars: Cognitive, Physical, and Immune Function00:22:03 [https://www.youtube.com/watch?v=1JediNaSMf4&t=1323s] - Clinical Trial Design: Crossover Trials & "Responder" Analysis00:27:12 [https://www.youtube.com/watch?v=1JediNaSMf4&t=1632s] - The Types of Teams & Interventions (From Gene Therapy to Public Health)00:32:06 [https://www.youtube.com/watch?v=1JediNaSMf4&t=1926s] - Handling "Wild West" Clinics & The Importance of Data Transparency00:35:02 [https://www.youtube.com/watch?v=1JediNaSMf4&t=2102s] - How Many Teams Will Make it to the Finals?00:37:41 [https://www.youtube.com/watch?v=1JediNaSMf4&t=2261s] - Safety, Ethics, and Regulatory Hurdles00:43:42 [https://www.youtube.com/watch?v=1JediNaSMf4&t=2622s] - The FDA's Role and the Challenge of Approving "Aging" Interventions00:51:18 [https://www.youtube.com/watch?v=1JediNaSMf4&t=3078s] - The Story of the TAME Trial: Goals, Design, and Why It Stalled00:58:23 [https://www.youtube.com/watch?v=1JediNaSMf4&t=3503s] - The Real Reasons TAME Wasn't Funded (NIH Peer Review & More)01:07:09 [https://www.youtube.com/watch?v=1JediNaSMf4&t=4029s] - The Future of Large-Scale Aging Trials01:13:25 [https://www.youtube.com/watch?v=1JediNaSMf4&t=4405s] - The Good, The Bad, and The "Pheromones": Crazy XPRIZE Submissions01:16:49 [https://www.youtube.com/watch?v=1JediNaSMf4&t=4609s] - Breakdown of Finalist Categories: Drugs, Biologics, Supplements, and Multimodal Approaches01:22:20 [https://www.youtube.com/watch?v=1JediNaSMf4&t=4940s] - A Companion Prize for Biomarker Discovery01:27:30 [https://www.youtube.com/watch?v=1JediNaSMf4&t=5250s] - The Problem with "Biological Age" and Epigenetic Clocks01:31:44 [https://www.youtube.com/watch?v=1JediNaSMf4&t=5504s] - The Ethics of Using Direct-to-Consumer Age Tests in ClinicsAbout XPRIZE:XPRIZE's mission is to inspire and empower humanity to achieve breakthroughs that accelerate an equitable, abundant future.Website: https://www.xprize.org/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbkJvbnY4aTBEb1hxOHpIYk9tVU9TSGxQVTU2UXxBQ3Jtc0tuZGRPNFNnVzNLcXBwYmVkYUpENkVoNFFEeS1mSk9EUk9aM19Zdjhuekc3WklNOEhCVGowMlZMWVM1OGdvQUlySlFuREFZVTQ0TEwtV2wyeDhHM0J6WU02dWR4SklEMFRhSmVKcTBDOWpBRG5fQ3RWWQ&q=https%3A%2F%2Fwww.xprize.org%2F&v=1JediNaSMf4]Get Involved: https://www.xprize.org/get-involved [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbkNQS0U5dXNnM2hYQTZueTBWTVlvSjgxQzVVd3xBQ3Jtc0tucGg0QVBPOXZHZ21rNnd4NlVMUEVWZzFMNWh1TXprcGs1X2hvOGhJRzQ4QW5mN1Fmdk56M1k0M3ItSTVoeWJ2T1dKMUI1cjB5OFZKc1ZyMG44cFppbVFSS0J3d1N0NUlEdnhGeTktVkJDVkd3dDRGSQ&q=https%3A%2F%2Fwww.xprize.org%2Fget-involved&v=1JediNaSMf4]LinkedIn:   / x-prize-foundation   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbjNmUWhPY2w5UUpubkNIZ0xKX1lNaVpEcHRTUXxBQ3Jtc0trZmpUZTdWUXlzQXE5Yy1IQVpEMVNxX0lhaFY5eUlya1BjNXJ1Y1FQWmZTZE9BU3FGd0R0Y04tQ0xrT0UxYnF4Q0NuRDNIRDdMUVZ4Ym8wcnptMmlwTEFjbTFGbklYTTJLMjgxZTdzZ0dkalhieDkwSQ&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fx-prize-foundation%2F&v=1JediNaSMf4]YouTube:    / xprize   [https://www.youtube.com/xprize]X: http://x.com/xprize [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa0tIZ1dIajBHU3BEZW9zZ2R1QV95b3RLTmJKQXxBQ3Jtc0trNG14bGc3XzZBZEhldTlmMWd0RklmQjhxamlWdnVmUlhJR3YtR04xTEVhS1F0ekhmVlN6dFZqQy1JdU5QdzQzRW01NFB6Zmh3YmlFMVRaZTA0bjF5V1lzeV9qX2tkSnptaXNOUnVUOFlDakt6bWRoMA&q=http%3A%2F%2Fx.com%2Fxprize&v=1JediNaSMf4]Instagram:   / xprize   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHJQVlE0VFN6VTFOT3BCZUR0MXJMQXNyM3BOd3xBQ3Jtc0ttOTJCOEpGWEhpY2lHQWVuUnk3Q0E0TmhXU2tlUUpOY0Fsckd1N2pwbjlVaGdPZnhaR0xsOEYtZGNOSmFDTXdhMVVkN2NaZXd5NGhFQXMxd2ZLWGR2NElsQ0F1MmdtaTlrRVdibDQtWEFPRjUxZ2VzUQ&q=https%3A%2F%2Fwww.instagram.com%2Fxprize%2F&v=1JediNaSMf4]TikTok:   / xprize   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbFV2S1lMX2Q5QnNmOFpPTllKYkRqOE80ekpTZ3xBQ3Jtc0tsZi04bFlKT2VLME15Z3JMVjdqN3VscVA2b1dLdW5xWWxtSjh1aGIxeldrZkFJMTE2RkNaUGFDdEF1dmZMTm12QnZTUkNtOXBmc21PQ01PUkdkSmo3elZfYTZyUW9RNmdNcDJHdEZLM1Vxb0EzWlc1dw&q=http%3A%2F%2Ftiktok.com%2F%40xprize&v=1JediNaSMf4]Facebook:   / xprize   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa0x2MzRmdEFjd3Q3cnBIUTRJRHdGQ0JiN2VWQXxBQ3Jtc0trTjlGeGlQWmNsQWxiTjFKMjJFRXZQSFM5NFhDWUZjc3FTNWJRQ055ZmIySmh5NUlESGZnc0kzN29ZQmRIdmRzYURPSTZyRFRxc3Y3a3lDUzd0cDUyNUZ1QmtEbHlqckNMc3VWWWFXQVV6S3pJNDVoQQ&q=http%3A%2F%2Ffacebook.com%2Fxprize&v=1JediNaSMf4]This video was produced by One Billion Media, an agency that specializes in YouTube virality for health brands and experts. Learn more about their work here:https://onebillionmedia.com/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbVpES3pPWWt2ZjRyeTFtQzIyUDFaeldzdS12UXxBQ3Jtc0trb2QxeHVEejhjWDg2Y3VOS3dZUDlyejR5YkotQ0NRXzlvcEpJRmlwYS0xXy0wZTZUeUlJM2w0aFlnakdOWUVQQmF3THB4LWcyQkhHTjd5S29lcFh6bDR0Mms3alNGV3F4RWIyU0cwOHZjeUlXcGcxdw&q=https%3A%2F%2Fonebillionmedia.com%2F&v=1JediNaSMf4]DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://x.com/Optispan_Inc [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHNRVEdCZHoxZ04zM0U2ai12WlE2M1Awd0hKQXxBQ3Jtc0trSWFuX0txMGhsQnpqMjlUcjFWT1g5SDB4bGZZNld5VVNGWmtCY3Y0MjN4eHlTWEJXNlloanNyMjNKdFZmWlB0MEg1amt1azdUQU1kQTk4V0lmMF85SEI4N3Z2Ykg0OF80WjNQdFRZX1NzRFVsalk3UQ&q=https%3A%2F%2Fx.com%2FOptispan_Inc&v=1JediNaSMf4]Twitter: https://x.com/mkaeberlein [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa0M5MW94RWlzX3RRdlRMVVRtZHVLVjdvNV8zUXxBQ3Jtc0ttUWpYQm9wS3hRT1FRcmY0TVByRWs3ejRxdmpia2g0ZnVsR2tMRUlfZk9WLTRaQ2VuNUVmZjZpNDRia2RGYW9zTFE5S2VacjVsRXQ4T3dWRXY5and5dG9YWGNkZURLVEwzZ1FhQXNYLTZmcHJpSkNxNA&q=https%3A%2F%2Fx.com%2Fmkaeberlein&v=1JediNaSMf4] Linkedin:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqblhrUGJvZVpxS1o4VEh3QmdQTVYyWDd4WHhld3xBQ3Jtc0treWtiVDg5NU83bGlCeXo5MGdDaTAtTUg0bnBpMTNMN0NCM3hlMnVpV2hhOWt4VjB1encxczc2eTJhMzhCb1RnQ3R3TVBMc095RUNRSHo1T1JfeTU4RDVDVXBENlZCcmF2VktWRjhlMjIxNWJOU19KMA&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Foptispan%2F&v=1JediNaSMf4]Instagram:   / optispan_   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqa3VEVE1tWVRUYWZjS2lCWFJVcnk0RDdyVGkyUXxBQ3Jtc0trLVIyQUtqMXI0NEtvNTY3OWp2YlFyS1EwR1lhbUFiRURzNGRDbXEzSmZIdkF2YWZPQzRubWdjSGpMS1NyOVlkTFhhR0FUUUhlLWQ0a19rR2VwTDdvX25mZDRpWnNTdUprZVNMdVRlZmI1Y0dhX2FUbw&q=https%3A%2F%2Fwww.instagram.com%2Foptispan_%2F&v=1JediNaSMf4] TikTok:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbWNRWHEyZ1NxT2hlMmpEVE9FbkdxMkFSbVB6QXxBQ3Jtc0ttNVgxSFcwS2xvRDBFTWI4VExNNFc3dWh4R1FtZ2lvcWxHdUpnakRjRzBFbHRIczVnRXM4eU5HY3NpSXM5dEQtS2hIcW0wMjRwcnZvYkR4OEJuc3U4RVRIRC1uX2NYM0U0V056Rm9YV1ZkLXAzZ3p2TQ&q=https%3A%2F%2Fwww.tiktok.com%2F%40optispan&v=1JediNaSMf4]https://www.optispan.life/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbTMzQS1OX1dlSHp3YV9ucHlFQzV5UGZ2X1VuZ3xBQ3Jtc0ttM3JDc202VXJEZ2Y1aTZNY0hJLWcyMEIwRVNnRFo2Wl9tOFlnMmpnR0w2OHgwUHMzQXRrNTJ3QnN0MnIwYWpOR2pabFNCdDA2Zm1qZGJvMzU4VWFaN0FxU3dtbHJEZHFNQ2hlbllxdEZMZGRuZlczdw&q=https%3A%2F%2Fwww.optispan.life%2F&v=1JediNaSMf4]Discover how teams worldwide are competing to prove they can reverse human aging by 10+ years, and why the winner might not be a drug at all.

Dr. Stanfield Mortgaged His House For $150k To Prove Longevity Drug Works

In this in-depth conversation, Dr. Brad Stanfield sits down with Dr Matt Kaeberlein to discuss his journey from a primary care physician in New Zealand to a leading voice in the evidence-based longevity space. We cover the launch and philosophy behind his YouTube channel, the challenges and exciting results of his self-funded rapamycin clinical trial, and his critical perspective on supplements, medical guidelines, and the future of aging research. Dr. Stanfield provides a unique clinician's viewpoint on hot topics like GLP-1 agonists (Ozempic), SGLT2 inhibitors, vitamin D testing, and the pitfalls of biological age clocks. We also dive into a spirited debate on the role of medical societies, the balance between risk and benefit in prescribing medications, and why he believes the field of longevity is still in its early stages of discovery. Key Topics & Timestamps: 00:00 - Introduction 00:52 - Brad's Background 02:47 - Starting the YouTube Channel & Philosophy on Science Communication 07:39 - The Rigor of Clinical Data vs. Misinformation 10:14 - Admitting Mistakes in Public (Resveratrol, Metformin) 14:40 - Funding and Designing the Rapamycin Clinical Trial 19:25 - Rapamycin Trial Results Submitted & Plans for a PhD 23:28 - Preventative Care: New Zealand vs. US Healthcare Systems 27:59 - The Vitamin D Debate: To Test or Not to Test? 35:18 - Trust in Medical Guidelines & The Hormone Replacement Therapy Controversy 43:42 - The Problem with Biological Age Clocks 46:22 - Patient-Centered Care: Inform vs. Decide in Medicine 49:49 - How to Judge the Quality of a Clinical Trial (CONSORT) 53:44 - Risk vs. Benefit: When Should We Prescribe Preventative Drugs? 58:05 - GLP-1 Agonists (Ozempic) and SGLT2 Inhibitors in Practice 01:02:00 - Brad's Personal Use of an SGLT2 Inhibitor 01:05:38 - The State of Longevity Research: How Much Do We Really Know? 01:08:34 - Closing Remarks DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. Dr. Brad Stanfield's Socials: Website: https://drstanfield.com/ YouTube: https://www.youtube.com/@DrBradStanfield [https://www.youtube.com/@DrBradStanfield] X: https://x.com/BradStanfieldMD More places to find us: Twitter: https://x.com/Optispan_Inc Twitter: https://x.com/mkaeberlein  Linkedin: https://www.linkedin.com/company/optispan/ Instagram: https://www.instagram.com/optispan_/   TikTok: https://www.tiktok.com/@optispan https://www.optispan.life/ [https://www.optispan.life/]

Don't Fall For This Scam: Matt's Deepfake PSA

Subscribe to our channel:    / @optispan   [https://www.youtube.com/channel/UCSna7385c3Xg_4Too92NKMw]Get Our Newsletter (It's Free): https://www.optispan.life/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbDVrckZuMkxwMGpQLTE2UU5fTl9XZ3pyWVhOd3xBQ3Jtc0tuVkxRLWVPbF81YlE4NlJ1U3ZLTDFtOEhwc2NaQjI4VUJ6ek9oaE5kX2hDczBWWWlnUmhBTnBtRkNvYUJ4RmRJWUlQUWdTQ1BQT3ZJUDZlMHZoUkwtNU02S0dwS2JUNTdvX3k4UXdqVS1vOFE0Z2FpOA&q=https%3A%2F%2Fwww.optispan.life%2F&v=83mwwj2VfII]DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://x.com/Optispan_Inc [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbjVGWHpqZGVkZFFjV0w5SHBTdG1FUGxaZEltZ3xBQ3Jtc0tsQkdmWDhZRlBmRHRDckNHbnFROGRXRVFhcXp3a0FIR0lOYm9hVXJKRllEWFZuakZ3RjdNbE5EMm0xZF94dXp0SW9OSUJOc3NWNUFoZU96dTA2dXVTOTdwNjdEdnZKVVluN3REamNlRGhLYXVFaW5sRQ&q=https%3A%2F%2Fx.com%2FOptispan_Inc&v=83mwwj2VfII]Twitter:   / mkaeberlein   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHhoQXRSTnJNUXpXYW5CM2U5RmxQMFFZVjZ1d3xBQ3Jtc0tucHd2QlJ4dHBGSWstSjY4MVpsUzEyei1zdU9Cdk1DLUNYWDl1MGVNX2drbXlEMk94Tjk4U0tMUjJvVU5sT21hQWJlMHZ1cXlVaU5YYUotbGxMSEFCNHdqVWFrZ1puZEtJUUNKcmFhZlNxMnpmVjE3UQ&q=https%3A%2F%2Ftwitter.com%2Fmkaeberlein&v=83mwwj2VfII]Linkedin:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbV9kUmp5TTlWX21tSUpYWTJMR09vMnk3NGhfZ3xBQ3Jtc0tud0JnZzNyOXpXU3g0UDFqODZNUFVQTjBzak51ZGQzLVhXVUppcTRJZUs2ak90Y0dqTWpYNWNUWm9hdEQ4WUl6RkRrRzg1azdFMEg1cXVGNHpjbDFDcUJYOWRGaFlfMjNrbUJVSlgxTE5ZVHB0LUpGOA&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Foptispan&v=83mwwj2VfII]Instagram:   / optispan_   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbnZ5eWw2Mm9OTVhidWV3UmJpZ0hEbzZlOVQxQXxBQ3Jtc0tudEEzMzc1N2tYZXl5TEVfZEpkOEZCVVVqX2JqNkI5eF9jNWVvSGJtV0NQN0QzMFpMY2ZCZVp0MWwwb09UYVcyLTA5dXlSbDV3TUdGTUxYRThlSkROQV9EMGpxdXd6eEN5Q0pJN21QWDFieS1mRUNGUQ&q=https%3A%2F%2Fwww.instagram.com%2Foptispan_%2F&v=83mwwj2VfII]TikTok:   / optispan   [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbjVHbkllQ2Y2VGNMVzExLUx4UFo1c0NJYVRzZ3xBQ3Jtc0trb0ljYkZZZUwtc2djLVFMVU9mUnppWjFlMnlxZElsaDJXXzdNSGxCdV9hV2N6VF9pTkx6UFp0WFlseUtjTXg3Vm5qRnB5RjQxQXc4N3N0V3Vxc2MzZzF1cDBYTm5lSTMwR1d5OGxERElQZ3pRUzlDaw&q=https%3A%2F%2Fwww.tiktok.com%2F%40optispan&v=83mwwj2VfII]https://www.optispan.life/ [https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbXh1Nm02eTFLSkNRZnA1NjFCdkpnUTFCclRqZ3xBQ3Jtc0tsRC04ZzgxMTdSa3J1OXFJQjVPWlNRVmZBandWVjd4WkctV1dxMDBCWjZ6QUNWR3JpOEQyNzA2Qi1rVjlYNDhHYlpEakgyLW5mSk9rVk9SNG9va3hHeXNpNGwtdzNlYlI1UjVDOGVYTzl1RkZlRUFuTQ&q=https%3A%2F%2Fwww.optispan.life%2F&v=83mwwj2VfII]Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!