This Podcast Will Kill You

Ep 167 Viagra/Sildenafil: Raising the bar

Has a name brand prescription medication ever shot to notoriety as quickly as Viagra did? Within a few months of its arrival on the market, it seems like everyone knew about the little blue pill, whether through commercials featuring celebrity spokespeople or from endless jokes on late night talk shows. But while everyone understood that this medication promised to treat erectile dysfunction, what most people didn’t know was the wild story leading to its development. Or how this medication (and similar medications) actually works. Or the tremendous impact this blockbuster drug would have on the ways that medications are advertised and developed. In this episode, we bring you those stories (and many more). Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAu [https://bit.ly/3WwtIAu] See omnystudio.com/listener [https://omnystudio.com/listener] for privacy information.

Ep 166 Amanita poisoning: Death Cap-tivating

In forests, in lawns, in city parks across the world lurks a small, pale, unassuming mushroom whose inconspicuous appearance belies its deadly nature. For within this mushroom dwelsl one of the deadliest poisons known to humans: amatoxin. It’s because of this toxin that the aptly-named ‘death cap mushroom’ (Amanita phalloides) is responsible for the vast majority of mushroom-related deaths around the globe each year. What makes this poisonous mushroom so very deadly, and is there anything we can do about it? In this episode, we take a journey through this legendary mushroom’s story, exploring its destructive biology, its murderous history, and its worrying yet hopeful future. Tune in to learn more about these mushrooms that show death can come in small packages. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAu [https://bit.ly/3WwtIAu] See omnystudio.com/listener [https://omnystudio.com/listener] for privacy information.

Ep 165 Fish Tongue Parasite: Parasite Appreciation Hour

Okay everyone, think about your tongue. Maybe move it around a bit, check in with it, consider what it means to you. Now imagine that your tongue suddenly shriveled up and fell off and that in its place is a tongue-sized isopod aka rollie pollie aka pillbug. Just there, hanging out, forever. How are you feeling? Horrified? Disgusted? Hey, we get it. But at least you’ll never be alone again. Believe it or not, this is not some bad creative writing exercise. This is a very real parasite. In fact, it’s not just one but a whole group of them. Fortunately for us humans, these tongue-replacing isopods don’t target mammals but rather various fish species (unfortunately for the fish). And in this week’s episode, we’re getting up close and personal with these bizarre (and dare we say cute?) organ-replacing parasites. If you’re wondering why on earth you should care about a niche parasite like this one or why it might be a bad idea to get rid of all of earth’s parasites, then we warmly invite you to sit back, relax, and enjoy this parasite appreciation hour. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAu [https://bit.ly/3WwtIAu] See omnystudio.com/listener [https://omnystudio.com/listener] for privacy information.

Ep 164 Rift Valley Fever: Ruminating on ruminants

Hemorrhagic virus? Check. Deadly disease? Check. Mosquito-borne? Check. Affected by animal movement, human activity, and environmental change? Check. Rift Valley Fever has all the markings of a classic TPWKY episode. This week, we’re doing a deep dive on this deadly virus, taking a One Health approach to explore the intricate relationships between animals, humans, and the environment to understand how this virus moves across the landscape. We trace the various paths this virus takes: through the organisms it infects, across the globe as it spreads, and over time as it appears to be evolving to be deadlier. Tune in to learn more about Rift Valley fever and what we might see with this pathogen in the years to come. Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAu [https://bit.ly/3WwtIAu] See omnystudio.com/listener [https://omnystudio.com/listener] for privacy information.

Ep 163 Circadian Rhythm: Live from Perth, Australia

We are coming at you with our very first live episode from Perth, Australia! Here at the 2024 Australian Institute of Occupational Hygienists [https://www.aioh.org.au/] Annual Scientific Conference and Exhibition [https://www.aioh.org.au/annual-conference/], occupational hazards and exposures get top billing. And one of the most ubiquitous hazards, experienced by nearly every industry is fatigue, specifically fatigue caused by circadian rhythm disruption. In this very special episode, we explore how our circadian rhythms work and some of the consequences that can emerge when we work against those rhythms, whether that’s because we’re traveling across many time zones or switching to night shift work. We then dig into the history of circadian rhythm research, from how we first learned about these daily patterns to when their disruption became a routine occurrence. Helping us to navigate some of the alarmist headlines (“your screens are ruining your sleep!”) and biohacker claims (“avoid jet lag with this one simple trick!”) is Ian Dunican, PhD [https://sleep4performance.com/about/]. Dr. Dunican is the Director and Chief Adviser of Melius Consulting [https://meliusconsulting.com.au/], a scientific consultancy undertaking research, consulting, and education, and he also hosts and produces the Sleep4Performance podcast [https://sleep4performance.com/podcast/]. We also bring on Dr. John Iliff [https://reliis.com.au/john-iliff/], Emergency Physician and Aeromedical Consultant to share his frightening experience with fatigue after a long shift during his training as a physician. Tune in for a fascinating discussion about the rhythms that drive our lives! Support this podcast by shopping our latest sponsor deals and promotions at this link: https://bit.ly/3WwtIAu [https://bit.ly/3WwtIAu] See omnystudio.com/listener [https://omnystudio.com/listener] for privacy information.